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Review

The molecular mechanisms of chemotherapeutic resistance in tumors (Review)

  • Authors:
    • Xin Weng
    • Wei-Hong Zeng
    • Li-Yuan Zhong
    • Li-Hua Xie
    • Wen-Jun Ge
    • Zhen Lai
    • Qin Qin
    • Peng Liu
    • De-Liang Cao
    • Xi Zeng
  • View Affiliations / Copyright

    Affiliations: Hunan Engineering Research Center for Early Diagnosis and Treatment of Liver Cancer, Hunan Province Key Laboratory of Tumor Cellular and Molecular Pathology, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, P.R China, Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410000, P.R. China, Department of Pathology, The First Affiliated Hospital of University of South China, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, P.R. China, Department of Gastroenterology, The First Affiliated Hospital (People's Hospital of Hunan), Hunan Normal University, Changsha, Hunan 410005, P.R. China
  • Article Number: 157
    |
    Published online on: September 30, 2024
       https://doi.org/10.3892/or.2024.8816
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Abstract

Chemotherapy remains a prevalent treatment for a wide range of tumors; however, the majority of patients undergoing conventional chemotherapy experience varying levels of chemoresistance, ultimately leading to suboptimal outcomes. The present article provided an in‑depth review of chemotherapy resistance in tumors, emphasizing the underlying factors contributing to this resistance in tumor cells. It also explored recent advancements in the identification of key molecules and molecular mechanisms within the primary chemoresistant pathways.
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Copy and paste a formatted citation
Spandidos Publications style
Weng X, Zeng W, Zhong L, Xie L, Ge W, Lai Z, Qin Q, Liu P, Cao D, Zeng X, Zeng X, et al: The molecular mechanisms of chemotherapeutic resistance in tumors (Review). Oncol Rep 52: 157, 2024.
APA
Weng, X., Zeng, W., Zhong, L., Xie, L., Ge, W., Lai, Z. ... Zeng, X. (2024). The molecular mechanisms of chemotherapeutic resistance in tumors (Review). Oncology Reports, 52, 157. https://doi.org/10.3892/or.2024.8816
MLA
Weng, X., Zeng, W., Zhong, L., Xie, L., Ge, W., Lai, Z., Qin, Q., Liu, P., Cao, D., Zeng, X."The molecular mechanisms of chemotherapeutic resistance in tumors (Review)". Oncology Reports 52.5 (2024): 157.
Chicago
Weng, X., Zeng, W., Zhong, L., Xie, L., Ge, W., Lai, Z., Qin, Q., Liu, P., Cao, D., Zeng, X."The molecular mechanisms of chemotherapeutic resistance in tumors (Review)". Oncology Reports 52, no. 5 (2024): 157. https://doi.org/10.3892/or.2024.8816
Copy and paste a formatted citation
x
Spandidos Publications style
Weng X, Zeng W, Zhong L, Xie L, Ge W, Lai Z, Qin Q, Liu P, Cao D, Zeng X, Zeng X, et al: The molecular mechanisms of chemotherapeutic resistance in tumors (Review). Oncol Rep 52: 157, 2024.
APA
Weng, X., Zeng, W., Zhong, L., Xie, L., Ge, W., Lai, Z. ... Zeng, X. (2024). The molecular mechanisms of chemotherapeutic resistance in tumors (Review). Oncology Reports, 52, 157. https://doi.org/10.3892/or.2024.8816
MLA
Weng, X., Zeng, W., Zhong, L., Xie, L., Ge, W., Lai, Z., Qin, Q., Liu, P., Cao, D., Zeng, X."The molecular mechanisms of chemotherapeutic resistance in tumors (Review)". Oncology Reports 52.5 (2024): 157.
Chicago
Weng, X., Zeng, W., Zhong, L., Xie, L., Ge, W., Lai, Z., Qin, Q., Liu, P., Cao, D., Zeng, X."The molecular mechanisms of chemotherapeutic resistance in tumors (Review)". Oncology Reports 52, no. 5 (2024): 157. https://doi.org/10.3892/or.2024.8816
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