Open Access

Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review)

  • Authors:
    • Xinchi Luan
    • Xuezhe Wang
    • Gang Bian
    • Xiaoxuan Li
    • Ziru Gao
    • Zijiao Liu
    • Zhishang Zhang
    • Tianyue Han
    • Jinpeng Zhao
    • Hongjiao Zhao
    • Xinyue Luan
    • Wuhui Zhu
    • Lili Dong
    • Feifei Guo
  • View Affiliations

  • Published online on: November 20, 2024     https://doi.org/10.3892/or.2024.8846
  • Article Number: 13
  • Copyright: © Luan et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a malignant neoplasm that typically manifests with subtle clinical manifestations in its early stages and frequently eludes diagnosis until the advanced phases of the disease. The limited therapeutic options available for PDAC significantly contribute to its high mortality rate, highlighting the urgent need for novel biomarkers capable of effectively identifying early clinical manifestations and facilitating precise diagnosis. The pivotal role of cellular exosomes in both the pathogenesis and therapeutic interventions for PDAC has been underscored. Furthermore, researchers have acknowledged the potential of exosomes as targeted drug carriers against regulatory cells in treating PDAC. The present article aims to provide a comprehensive review encompassing recent advancements in utilizing exosomes for elucidating mechanisms underlying disease development, patterns of metastasis, diagnostic techniques and treatment strategies associated with PDAC.
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January-2025
Volume 53 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Luan X, Wang X, Bian G, Li X, Gao Z, Liu Z, Zhang Z, Han T, Zhao J, Zhao H, Zhao H, et al: Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review). Oncol Rep 53: 13, 2025.
APA
Luan, X., Wang, X., Bian, G., Li, X., Gao, Z., Liu, Z. ... Guo, F. (2025). Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review). Oncology Reports, 53, 13. https://doi.org/10.3892/or.2024.8846
MLA
Luan, X., Wang, X., Bian, G., Li, X., Gao, Z., Liu, Z., Zhang, Z., Han, T., Zhao, J., Zhao, H., Luan, X., Zhu, W., Dong, L., Guo, F."Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review)". Oncology Reports 53.1 (2025): 13.
Chicago
Luan, X., Wang, X., Bian, G., Li, X., Gao, Z., Liu, Z., Zhang, Z., Han, T., Zhao, J., Zhao, H., Luan, X., Zhu, W., Dong, L., Guo, F."Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review)". Oncology Reports 53, no. 1 (2025): 13. https://doi.org/10.3892/or.2024.8846