|
1
|
Torre LA, Islami F, Siegel RL, Ward EM and
Jemal A: Global cancer in women: Burden and trends. Cancer
Epidemiol Biomarkers Prev. 26:444–457. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Abu Samaan TM, Samec M, Liskova A, Kubatka
P and Büsselberg D: Paclitaxel's mechanistic and clinical effects
on breast cancer. Biomolecules. 9:7892019. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Vu M, Yu J, Awolude OA and Chuang L:
Cervical cancer worldwide. Curr Probl Cancer. 42:457–465. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ledermann JA: Front-line therapy of
advanced ovarian cancer: New approaches. Ann Oncol. 28
(Suppl_8):viii46–viii50. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Fillon M: Opportunistic salpingectomy may
reduce ovarian cancer risk. CA Cancer J Clin. 72:97–99. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Torre LA, Trabert B, DeSantis CE, Miller
KD, Samimi G, Runowicz CD, Gaudet MM, Jemal A and Siegel RL:
Ovarian cancer statistics, 2018. CA Cancer J Clin. 68:284–296.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Mirza MR, Coleman RL, González-Martín A,
Moore KN, Colombo N, Ray-Coquard I and Pignata S: The forefront of
ovarian cancer therapy: Update on PARP inhibitors. Ann Oncol.
31:1148–1159. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kalampokas E, Giannis G, Kalampokas T,
Papathanasiou AA, Mitsopoulou D, Tsironi E, Triantafyllidou O,
Gurumurthy M, Parkin DE, Cairns M and Vlahos NF: Current approaches
to the management of patients with endometrial cancer. Cancers
(Basel). 14:45002022. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Brooks RA, Fleming GF, Lastra RR, Lee NK,
Moroney JW, Son CH, Tatebe K and Veneris JL: Current
recommendations and recent progress in endometrial cancer. CA
Cancer J Clin. 69:258–279. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dolma S, Lessnick SL, Hahn WC and
Stockwell BR: Identification of genotype-selective antitumor agents
using synthetic lethal chemical screening in engineered human tumor
cells. Cancer Cell. 3:285–296. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta
R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS,
et al: Ferroptosis: An iron-dependent form of nonapoptotic cell
death. Cell. 149:1060–1072. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Conrad M and Pratt DA: The chemical basis
of ferroptosis. Nat Chem Biol. 15:1137–1147. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yi J, Zhu J, Wu J, Thompson CB and Jiang
X: Oncogenic activation of PI3K-AKT-mTOR signaling suppresses
ferroptosis via SREBP-mediated lipogenesis. Proc Natl Acad Sci USA.
117:31189–31197. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Friedmann Angeli JP, Krysko DV and Conrad
M: Ferroptosis at the crossroads of cancer-acquired drug resistance
and immune evasion. Nat Rev Cancer. 19:405–414. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Lei G, Zhuang L and Gan B: Targeting
ferroptosis as a vulnerability in cancer. Nat Rev Cancer.
22:381–396. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mao X, Liu K, Shen S, Meng L and Chen S:
Ferroptosis, a new form of cell death: Mechanisms, biology and role
in gynecological malignant tumor. Am J Cancer Res. 13:2751–2762.
2023.PubMed/NCBI
|
|
17
|
Chen Z, Han F, Du Y, Shi H and Zhou W:
Hypoxic microenvironment in cancer: Molecular mechanisms and
therapeutic interventions. Signal Transduct Target Ther. 8:702023.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wu Q, You L, Nepovimova E, Heger Z, Wu W,
Kuca K and Adam V: Hypoxia-inducible factors: Master regulators of
hypoxic tumor immune escape. J Hematol Oncol. 15:772022. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Semenza GL: Pharmacologic targeting of
Hypoxia-inducible factors. Annu Rev Pharmacol Toxicol. 59:379–403.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Fuhrmann DC, Mondorf A, Beifuß J, Jung M
and Brüne B: Hypoxia inhibits ferritinophagy, increases
mitochondrial ferritin, and protects from ferroptosis. Redox Biol.
36:1016702020. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Fuhrmann DC and Brüne B: A graphical
journey through iron metabolism, microRNAs, and hypoxia in
ferroptosis. Redox Biol. 54:1023652022. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Feng X, Wang S, Sun Z, Dong H, Yu H, Huang
M and Gao X: Ferroptosis enhanced diabetic renal tubular injury via
HIF-1α/HO-1 pathway in db/db mice. Front Endocrinol (Lausanne).
12:6263902021. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Yuan S, Wei C, Liu G, Zhang L, Li J, Li L,
Cai S and Fang L: Sorafenib attenuates liver fibrosis by triggering
hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway. Cell
Prolif. 55:e131582022. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Liu XJ, Lv YF, Cui WZ, Li Y, Liu Y, Xue YT
and Dong F: Icariin inhibits hypoxia/reoxygenation-induced
ferroptosis of cardiomyocytes via regulation of the Nrf2/HO-1
signaling pathway. FEBS Open Bio. 11:2966–2976. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Adrover JM, McDowell SAC, He XY, Quail DF
and Egeblad M: NETworking with cancer: The bidirectional interplay
between cancer and neutrophil extracellular traps. Cancer Cell.
41:505–526. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ge W and Wu W: Influencing Factors and
significance of Tumor-associated Macrophage polarization in tumor
microenvironment. Zhongguo Fei Ai Za Zhi. 26:228–237. 2023.(In
Chinese). PubMed/NCBI
|
|
27
|
Hernansanz-Agustín P, Choya-Foces C,
Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L,
Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, et al: Na+
controls hypoxic signalling by the mitochondrial respiratory chain.
Nature. 586:287–291. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Jung J, Zhang Y, Celiku O, Zhang W, Song
H, Williams BJ, Giles AJ, Rich JN, Abounader R, Gilbert MR and Park
DM: Mitochondrial NIX promotes tumor survival in the hypoxic niche
of glioblastoma. Cancer Res. 79:5218–5232, 20193. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Kuo CL, Ponneri Babuharisankar A, Lin YC,
Lien HW, Lo YK, Chou HY, Tangeda V, Cheng LC, Cheng AN and Lee AY:
Mitochondrial oxidative stress in the tumor microenvironment and
cancer immunoescape: Foe or friend? J Biomed Sci. 29:742022.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Xiao C, Wang X, Li S, Zhang Z, Li J, Deng
Q, Chen X, Yang X and Li Z: A cuproptosis-based nanomedicine
suppresses triple negative breast cancers by regulating tumor
microenvironment and eliminating cancer stem cells. Biomaterials.
313:1227632025. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Doll S, Proneth B, Tyurina YY, Panzilius
E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A,
et al: ACSL4 dictates ferroptosis sensitivity by shaping cellular
lipid composition. Nat Chem Biol. 13:91–98. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Dixon SJ, Winter GE, Musavi LS, Lee ED,
Snijder B, Rebsamen M, Superti-Furga G and Stockwell BR: Human
haploid cell genetics reveals roles for lipid metabolism genes in
nonapoptotic cell death. ACS Chem Biol. 10:1604–1609. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yuan H, Li X, Zhang X, Kang R and Tang D:
Identification of ACSL4 as a biomarker and contributor of
ferroptosis. Biochem Biophys Res Commun. 478:1338–1343. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zou Y, Li H, Graham ET, Deik AA, Eaton JK,
Wang W, Sandoval-Gomez G, Clish CB, Doench JG and Schreiber SL:
Cytochrome P450 oxidoreductase contributes to phospholipid
peroxidation in ferroptosis. Nat Chem Biol. 16:302–309. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Koleini N, Shapiro JS, Geier J and
Ardehali H: Ironing out mechanisms of iron homeostasis and
disorders of iron deficiency. J Clin Invest. 131:e1486712021.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Luck AN and Mason AB: Transferrin-mediated
cellular iron delivery. Curr Top Membr. 69:3–35. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Mancias JD, Wang X, Gygi SP, Harper JW and
Kimmelman AC: Quantitative proteomics identifies NCOA4 as the cargo
receptor mediating ferritinophagy. Nature. 509:105–109. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Yambire KF, Rostosky C, Watanabe T,
Pacheu-Grau D, Torres-Odio S, Sanchez-Guerrero A, Senderovich O,
Meyron-Holtz EG, Milosevic I, Frahm J, et al: Impaired lysosomal
acidification triggers iron deficiency and inflammation in vivo.
Elife. 8:e510312019. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Zhang DD: Ironing out the details of
ferroptosis. Nat Cell Biol. 26:1386–1393. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Chen X, Yu C, Kang R, Kroemer G and Tang
D: Cellular degradation systems in ferroptosis. Cell Death Differ.
28:1135–1148. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Liu J, Kang R and Tang D: Signaling
pathways and defense mechanisms of ferroptosis. FEBS J.
289:7038–7050. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Bersuker K, Hendricks JM, Li Z, Magtanong
L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ and Zoncu R: The
CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit
ferroptosis. Nature. 575:688–692. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Doll S, Freitas FP, Shah R, Aldrovandi M,
da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius
E, Scheel CH, et al: FSP1 is a glutathione-independent ferroptosis
suppressor. Nature. 575:693–698. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Garcia-Bermudez J and Birsoy K: A
mitochondrial gatekeeper that helps cells escape death by
ferroptosis. Nature. 593:514–515. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee
H, Koppula P, Wu S, Zhuang L, Fang B, et al: DHODH-mediated
ferroptosis defence is a targetable vulnerability in cancer.
Nature. 593:586–590. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Zhao L, Zhou X, Xie F and Zhang L, Yan H,
Huang J, Zhang C, Zhou F, Chen J and Zhang L: Ferroptosis in cancer
and cancer immunotherapy. Cancer Commun (Lond). 42:88–116. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Kraft VAN, Bezjian CT, Pfeiffer S,
Ringelstetter L, Müller C, Zandkarimi F, Merl-Pham J, Bao X,
Anastasov N, Kössl J, et al: GTP Cyclohydrolase
1/Tetrahydrobiopterin Counteract Ferroptosis through lipid
remodeling. ACS Cent Sci. 6:41–53. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Yagoda N, von Rechenberg M, Zaganjor E,
Bauer AJ, Yang WS, Fridman DJ, Wolpaw AJ, Smukste I, Peltier JM,
Boniface JJ, et al: RAS-RAF-MEK-dependent oxidative cell death
involving voltage-dependent anion channels. Nature. 447:864–868.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Yang WS and Stockwell BR: Synthetic lethal
screening identifies compounds activating iron-dependent,
nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.
Chem Biol. 15:234–245. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Tomaskova Z, Gaburjakova J, Brezova A and
Gaburjakova M: Inhibition of anion channels derived from
mitochondrial membranes of the rat heart by stilbene
disulfonate-DIDS. J Bioenerg Biomembr. 39:301–311. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Xue X, Ramakrishnan SK, Weisz K, Triner D,
Xie L, Attili D, Pant A, Győrffy B, Zhan M, Carter-Su C, et al:
Iron uptake via DMT1 integrates cell cycle with JAK-STAT3 signaling
to promote colorectal tumorigenesis. Cell Metab. 24:447–461. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Song Q, Peng S, Sun Z, Heng X and Zhu X:
Temozolomide drives ferroptosis via a DMT1-Dependent pathway in
glioblastoma cells. Yonsei Med J. 62:843–849. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Li J, Lama R, Galster SL, Inigo JR, Wu J,
Chandra D, Chemler SR and Wang X: Small-Molecule MMRi62 induces
ferroptosis and inhibits metastasis in pancreatic cancer via
degradation of ferritin heavy chain and mutant p53. Mol Cancer
Ther. 21:535–545. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Feng J, Lu PZ, Zhu GZ, Hooi SC, Wu Y,
Huang XW, Dai HQ, Chen PH, Li ZJ, Su WJ, et al: ACSL4 is a
predictive biomarker of sorafenib sensitivity in hepatocellular
carcinoma. Acta Pharmacol Sin. 42:160–170. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Wenz C, Faust D, Linz B, Turmann C,
Nikolova T, Bertin J, Gough P, Wipf P, Schröder AS, Krautwald S and
Dietrich C: t-BuOOH induces ferroptosis in human and murine cell
lines. Arch Toxicol. 92:759–775. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Yang WS, SriRamaratnam R, Welsch ME,
Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji
AF and Clish CB: Regulation of ferroptotic cancer cell death by
GPX4. Cell. 156:317–331. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Li J, Cao F, Yin HL, Huang ZJ, Lin ZT, Mao
N, Sun B and Wang G: Ferroptosis: Past, present and future. Cell
Death Dis. 11:882020. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Wu Z, Geng Y, Lu X, Shi Y, Wu G, Zhang M,
Shan B, Pan H and Yuan J: Chaperone-mediated autophagy is involved
in the execution of ferroptosis. Proc Natl Acad Sci USA.
116:2996–3005. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Yoshioka H, Kawamura T, Muroi M, Kondoh Y,
Honda K, Kawatani M, Aono H, Waldmann H, Watanabe N and Osada H:
Identification of a small molecule that enhances ferroptosis via
inhibition of ferroptosis suppressor protein 1 (FSP1). ACS Chem
Biol. 17:483–491. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Zhao Y, Yin W, Yang Z, Sun J, Chang J,
Huang L, Xue L, Zhang X, Zhi H, Chen S, et al:
Nanotechnology-enabled M2 macrophage polarization and ferroptosis
inhibition for targeted inflammatory bowel disease treatment. J
Control Release. 367:339–353. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Zhang H, Deng T, Liu R, Ning T, Yang H,
Liu D, Zhang Q, Lin D, Ge S, Bai M, et al: CAF secreted miR-522
suppresses ferroptosis and promotes acquired chemo-resistance in
gastric cancer. Mol Cancer. 19:432020. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Ishii T, Bannai S and Sugita Y: Mechanism
of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro.
Role of the mixed disulfide of 2-mercaptoethanol and cysteine. J
Biol Chem. 256:12387–12392. 1981. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Gordon S: Alternative activation of
macrophages. Nat Rev Immunol. 3:23–35. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Murdoch C, Giannoudis A and Lewis CE:
Mechanisms regulating the recruitment of macrophages into hypoxic
areas of tumors and other ischemic tissues. Blood. 104:2224–2234.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Boutilier AJ and Elsawa SF: Macrophage
polarization states in the tumor microenvironment. Int J Mol Sci.
22:69952021. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Yin M, Li X, Tan S, Zhou HJ, Ji W, Bellone
S, Xu X, Zhang H, Santin AD, Lou G and Min W: Tumor-associated
macrophages drive spheroid formation during early transcoelomic
metastasis of ovarian cancer. J Clin Invest. 126:4157–4173. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Recalcati S, Locati M, Gammella E,
Invernizzi P and Cairo G: Iron levels in polarized macrophages:
Regulation of immunity and autoimmunity. Autoimmun Rev. 11:883–889.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Gu Z, Liu T, Liu C, Yang Y, Tang J, Song
H, Wang Y, Yang Y and Yu C: Ferroptosis-strengthened metabolic and
inflammatory regulation of Tumor-associated macrophages provokes
potent tumoricidal activities. Nano Lett. 21:6471–6479. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Hao X, Zheng Z, Liu H, Zhang Y, Kang J,
Kong X, Rong D, Sun G, Sun G, Liu L, et al: Inhibition of APOC1
promotes the transformation of M2 into M1 macrophages via the
ferroptosis pathway and enhances anti-PD1 immunotherapy in
hepatocellular carcinoma based on single-cell RNA sequencing. Redox
Biol. 56:1024632022. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Li LG, Peng XC, Yu TT, Xu HZ, Han N, Yang
XX, Li QR, Hu J, Liu B, Yang ZY, et al: Dihydroartemisinin remodels
macrophage into an M1 phenotype via ferroptosis-mediated DNA
damage. Front Pharmacol. 13:9498352022. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Recalcati S, Locati M, Marini A,
Santambrogio P, Zaninotto F, De Pizzol M, Zammataro L, Girelli D
and Cairo G: Differential regulation of iron homeostasis during
human macrophage polarized activation. Eur J Immunol. 40:824–835.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Zhao YY, Lian JX, Lan Z, Zou KL, Wang WM
and Yu GT: Ferroptosis promotes anti-tumor immune response by
inducing immunogenic exposure in HNSCC. Oral Dis. 29:933–941. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Chen W, Zuo F, Zhang K, Xia T, Lei W,
Zhang Z, Bao L and You Y: Exosomal MIF derived from nasopharyngeal
carcinoma promotes metastasis by repressing ferroptosis of
macrophages. Front Cell Dev Biol. 9:7911872021. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Jakubczyk K, Dec K, Kałduńska J, Kawczuga
D, Kochman J and Janda K: Reactive oxygen species-sources,
functions, oxidative damage. Pol Merkur Lekarski. 48:124–127.
2020.PubMed/NCBI
|
|
75
|
Wang W, Green M, Choi JE, Gijón M, Kennedy
PD, Johnson JK, Liao P, Lang X, Kryczek I, Sell A, et al: CD8+ T
cells regulate tumour ferroptosis during cancer immunotherapy.
Nature. 569:270–274. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Haschka D, Hoffmann A and Weiss G: Iron in
immune cell function and host defense. Semin Cell Dev Biol.
115:27–36. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Wen ZF, Liu H, Gao R, Zhou M, Ma J, Zhang
Y, Zhao J, Chen Y, Zhang T, Huang F, et al: Tumor cell-released
autophagosomes (TRAPs) promote immunosuppression through induction
of M2-like macrophages with increased expression of PD-L1. J
Immunother Cancer. 6:1512018. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Farhood B, Najafi M and Mortezaee K: CD8+
cytotoxic T lymphocytes in cancer immunotherapy: A review. J Cell
Physiol. 234:8509–8521. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Yang L, Guo J, Yu N, Liu Y, Song H, Niu J
and Gu Y: Tocilizumab mimotope alleviates kidney injury and
fibrosis by inhibiting IL-6 signaling and ferroptosis in UUO model.
Life Sci. 261:1184872020. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Carmona-Cuenca I, Roncero C, Sancho P,
Caja L, Fausto N, Fernández M and Fabregat I: Upregulation of the
NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its
pro-apoptotic activity. J Hepatol. 49:965–976. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Yang L, Xing R, Li C, Liu Y, Sun L, Liu X
and Wang Y: Active immunization with Tocilizumab mimotopes induces
specific immune responses. BMC Biotechnol. 15:462015. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Chen P, Wang D, Xiao T, Gu W, Yang H, Yang
M and Wang H: ACSL4 promotes ferroptosis and M1 macrophage
polarization to regulate the tumorigenesis of nasopharyngeal
carcinoma. Int Immunopharmacol. 122:1106292023. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Puylaert P, Roth L, Van Praet M, Pintelon
I, Dumitrascu C, van Nuijs A, Klejborowska G, Guns PJ, Berghe TV,
Augustyns K, et al: Effect of erythrophagocytosis-induced
ferroptosis during angiogenesis in atherosclerotic plaques.
Angiogenesis. 26:505–522. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Tang R, Xu J, Zhang B, Liu J, Liang C, Hua
J, Meng Q, Yu X and Shi S: Ferroptosis, necroptosis, and pyroptosis
in anticancer immunity. J Hematol Oncol. 13:1102020. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Wen Q, Liu J, Kang R, Zhou B and Tang D:
The release and activity of HMGB1 in ferroptosis. Biochem Biophys
Res Commun. 510:278–283. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Dai E, Han L, Liu J, Xie Y, Kroemer G,
Klionsky DJ, Zeh HJ, Kang R, Wang J and Tang D: Autophagy-dependent
ferroptosis drives tumor-associated macrophage polarization via
release and uptake of oncogenic KRAS protein. Autophagy.
16:2069–2083. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Takei H, Araki A, Watanabe H, Ichinose A
and Sendo F: Rapid killing of human neutrophils by the potent
activator phorbol 12-myristate 13-acetate (PMA) accompanied by
changes different from typical apoptosis or necrosis. J Leukoc
Biol. 59:229–240. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Fuchs TA, Abed U, Goosmann C, Hurwitz R,
Schulze I, Wahn V, Weinrauch Y, Brinkmann V and Zychlinsky A: Novel
cell death program leads to neutrophil extracellular traps. J Cell
Biol. 176:231–241. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Papayannopoulos V and Zychlinsky A: NETs:
A new strategy for using old weapons. Trends Immunol. 30:513–521.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Monti M, De Rosa V, Iommelli F, Carriero
MV, Terlizzi C, Camerlingo R, Di Minno G and Del Vecchio S:
Neutrophil extracellular traps as an adhesion substrate for
different tumor cells expressing RGD-Binding integrins. Int J Mol
Sci. 19:23502018. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Pieterse E, Rother N, Garsen M, Hofstra
JM, Satchell SC, Hoffmann M, Loeven MA, Knaapen HK, van der Heijden
OWH, Berden JHM, et al: Neutrophil extracellular traps drive
Endothelial-to-mesenchymal transition. Arterioscler Thromb Vasc
Biol. 37:1371–1379. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Xiao Y, Cong M, Li J, He D, Wu Q, Tian P,
Wang Y, Yang S, Liang C, Liang Y, et al: Cathepsin C promotes
breast cancer lung metastasis by modulating neutrophil infiltration
and neutrophil extracellular trap formation. Cancer Cell.
39:423–437.e7. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Xia X, Zhang Z, Zhu C, Ni B, Wang S, Yang
S, Yu F, Zhao E, Li Q and Zhao G: Neutrophil extracellular traps
promote metastasis in gastric cancer patients with postoperative
abdominal infectious complications. Nat Commun. 13:10172022.
View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Awasthi D and Sarode A: Neutrophils at the
crossroads: Unraveling the multifaceted role in the tumor
microenvironment. Int J Mol Sci. 25:29292024. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Li C, Chen T, Liu J, Wang Y, Zhang C, Guo
L, Shi D, Zhang T, Wang X and Li J: FGF19-induced inflammatory CAF
promoted neutrophil extracellular trap formation in the liver
metastasis of colorectal cancer. Adv Sci (Weinh). 10:e23026132023.
View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Yang L, Liu Q, Zhang X, Liu X, Zhou B,
Chen J, Huang D, Li J, Li H, Chen F, et al: DNA of neutrophil
extracellular traps promotes cancer metastasis via CCDC25. Nature.
583:133–138. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Lee W, Ko SY, Mohamed MS, Kenny HA,
Lengyel E and Naora H: Neutrophils facilitate ovarian cancer
premetastatic niche formation in the omentum. J Exp Med.
216:176–194. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Aldabbous L, Abdul-Salam V, McKinnon T,
Duluc L, Pepke-Zaba J, Southwood M, Ainscough AJ, Hadinnapola C,
Wilkins MR, Toshner M and Wojciak-Stothard B: Neutrophil
extracellular traps promote angiogenesis: Evidence from vascular
pathology in pulmonary hypertension. Arterioscler Thromb Vasc Biol.
36:2078–2087. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
99
|
Zhang H, Wu D, Wang Y, Guo K, Spencer CB,
Ortoga L, Qu M, Shi Y, Shao Y, Wang Z, et al: METTL3-mediated
N6-methyladenosine exacerbates ferroptosis via
m6A-IGF2BP2-dependent mitochondrial metabolic reprogramming in
sepsis-induced acute lung injury. Clin Transl Med. 13:e13892023.
View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Zhang Y and Ertl HC: Starved and
Asphyxiated: How Can CD8(+) T cells within a tumor microenvironment
prevent tumor progression. Front Immunol. 7:322016. View Article : Google Scholar : PubMed/NCBI
|
|
101
|
Chen X, Song M, Zhang B and Zhang Y:
Reactive oxygen species regulate T cell immune response in the
tumor microenvironment. Oxid Med Cell Longev. 2016:15809672016.
View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Demers M, Krause DS, Schatzberg D,
Martinod K, Voorhees JR, Fuchs TA, Scadden DT and Wagner DD:
Cancers predispose neutrophils to release extracellular DNA traps
that contribute to cancer-associated thrombosis. Proc Natl Acad Sci
USA. 109:13076–13081. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Yao L, Sheng X, Dong X, Zhou W, Li Y, Ma
X, Song Y, Dai H and Du Y: Neutrophil extracellular traps mediate
TLR9/Merlin axis to resist ferroptosis and promote triple negative
breast cancer progression. Apoptosis. 28:1484–1495. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Zhang W: The mitophagy receptor FUN14
domain-containing 1 (FUNDC1): A promising biomarker and potential
therapeutic target of human diseases. Genes Dis. 8:640–654. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Al-Faze R, Ahmed HA, El-Atawy MA, Zagloul
H, Alshammari EM, Jaremko M, Emwas AH, Nabil GM and Hanna DH:
Mitochondrial dysfunction route as a possible biomarker and therapy
target for human cancer. Biomed J. March 5–2024.(Epub ahead of
print). View Article : Google Scholar : PubMed/NCBI
|
|
106
|
Sugioka R, Shimizu S and Tsujimoto Y:
Fzo1, a protein involved in mitochondrial fusion, inhibits
apoptosis. J Biol Chem. 279:52726–52734. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Chen QM: Nrf2 for protection against
oxidant generation and mitochondrial damage in cardiac injury. Free
Radic Biol Med. 179:133–143. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Tian C, Liu Y, Li Z, Zhu P and Zhao M:
Mitochondria related cell death modalities and disease. Front Cell
Dev Biol. 10:8323562022. View Article : Google Scholar : PubMed/NCBI
|
|
109
|
Li Y, Wang X, Huang Z, Zhou Y, Xia J, Hu
W, Wang X, Du J, Tong X and Wang Y: CISD3 inhibition drives
cystine-deprivation induced ferroptosis. Cell Death Dis.
12:8392021. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Yu F, Zhang Q, Liu H, Liu J, Yang S, Luo
X, Liu W, Zheng H, Liu Q, Cui Y, et al: Dynamic O-GlcNAcylation
coordinates ferritinophagy and mitophagy to activate ferroptosis.
Cell Discov. 8:402022. View Article : Google Scholar : PubMed/NCBI
|
|
111
|
Yu Z, Cao W, Ren Y, Zhang Q and Liu J:
ATPase copper transporter A, negatively regulated by miR-148a-3p,
contributes to cisplatin resistance in breast cancer cells. Clin
Transl Med. 10:57–73. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
112
|
Finney L, Mandava S, Ursos L, Zhang W,
Rodi D, Vogt S, Legnini D, Maser J, Ikpatt F and Olopade OI: X-ray
fluorescence microscopy reveals large-scale relocalization and
extracellular translocation of cellular copper during angiogenesis.
Proc Natl Acad Sci USA. 104:2247–2252. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
113
|
Lopez J, Ramchandani D and Vahdat L:
Copper depletion as a therapeutic strategy in cancer. Met Ions Life
Sci. 303–330. 2019.PubMed/NCBI
|
|
114
|
Shanbhag VC, Gudekar N, Jasmer K,
Papageorgiou C, Singh K and Petris MJ: Copper metabolism as a
unique vulnerability in cancer. Biochim Biophys Acta Mol Cell Res.
1868:1188932021. View Article : Google Scholar : PubMed/NCBI
|
|
115
|
Lossow K, Schwarz M and Kipp AP: Are trace
element concentrations suitable biomarkers for the diagnosis of
cancer? Redox Biol. 42:1019002021. View Article : Google Scholar : PubMed/NCBI
|
|
116
|
Chen L, Min J and Wang F: Copper
homeostasis and cuproptosis in health and disease. Signal Transduct
Target Ther. 7:3782022. View Article : Google Scholar : PubMed/NCBI
|
|
117
|
Tsvetkov P, Detappe A, Cai K, Keys HR,
Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, et al:
Mitochondrial metabolism promotes adaptation to proteotoxic stress.
Nat Chem Biol. 15:681–689. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
118
|
Mayr JA, Feichtinger RG, Tort F, Ribes A
and Sperl W: Lipoic acid biosynthesis defects. J Inherit Metab Dis.
37:553–563. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
119
|
Solmonson A and DeBerardinis RJ: Lipoic
acid metabolism and mitochondrial redox regulation. J Biol Chem.
293:7522–7530. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
120
|
Brewer GJ, Askari F, Lorincz MT, Carlson
M, Schilsky M, Kluin KJ, Hedera P, Moretti P, Fink JK, Tankanow R,
et al: Treatment of Wilson disease with ammonium
tetrathiomolybdate: IV. Comparison of tetrathiomolybdate and
trientine in a double-blind study of treatment of the neurologic
presentation of Wilson disease. Arch Neurol. 63:521–527. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
121
|
Chen T, Liang L, Wang Y, Li X and Yang C:
Ferroptosis and cuproptposis in kidney diseases: Dysfunction of
cell metabolism. Apoptosis. 29:289–302. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
122
|
He B, Liao Y, Tian M, Tang C, Tang Q, Ma
F, Zhou W, Leng Y and Zhong D: Identification and verification of a
novel signature that combines cuproptosis-related genes with
ferroptosis-related genes in osteoarthritis using bioinformatics
analysis and experimental validation. Arthritis Res Ther.
26:1002024. View Article : Google Scholar : PubMed/NCBI
|
|
123
|
Luo G, Wang L, Zheng Z, Gao B and Lei C:
Cuproptosis-related ferroptosis genes for predicting prognosis in
kidney renal clear cell carcinoma. Eur J Med Res. 28:1762023.
View Article : Google Scholar : PubMed/NCBI
|
|
124
|
Xue Q, Yan D, Chen X, Li X, Kang R,
Klionsky DJ, Kroemer G, Chen X, Tang D and Liu J: Copper-dependent
autophagic degradation of GPX4 drives ferroptosis. Autophagy.
19:1982–1996. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
125
|
Xiong C, Ling H, Hao Q and Zhou X:
Cuproptosis: A53-regulated metabolic cell death? Cell Death Differ.
30:876–884. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
126
|
Shao L, Zhu L, Su R, Yang C, Gao X, Xu Y,
Wang H, Guo C and Li H: Baicalin enhances the chemotherapy
sensitivity of oxaliplatin-resistant gastric cancer cells by
activating p53-mediated ferroptosis. Sci Rep. 14:107452024.
View Article : Google Scholar : PubMed/NCBI
|
|
127
|
Zou Y, Palte MJ, Deik AA, Li H, Eaton JK,
Wang W, Tseng YY, Deasy R, Kost-Alimova M, Dančík V, et al: A
GPX4-dependent cancer cell state underlies the clear-cell
morphology and confers sensitivity to ferroptosis. Nat Commun.
10:16172019. View Article : Google Scholar : PubMed/NCBI
|
|
128
|
Lu Y, Qin H, Jiang B, Lu W, Hao J, Cao W,
Du L, Chen W, Zhao X, Guo H, et al: KLF2 inhibits cancer cell
migration and invasion by regulating ferroptosis through GPX4 in
clear cell renal cell carcinoma. Cancer Lett. 522:1–13. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
129
|
Gradishar WJ, Moran MS, Abraham J, Aft R,
Agnese D, Allison KH, Anderson B, Burstein HJ, Chew H, Dang C, et
al: Breast cancer, version 3.2022, NCCN clinical practice
guidelines in oncology. J Natl Compr Canc Netw. 20:691–722. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
130
|
Zou Y, Zheng S, Xie X, Ye F, Hu X, Tian Z,
Yan SM, Yang L, Kong Y, Tang Y, et al: N6-methyladenosine regulated
FGFR4 attenuates ferroptotic cell death in recalcitrant
HER2-positive breast cancer. Nat Commun. 13:26722022. View Article : Google Scholar : PubMed/NCBI
|
|
131
|
Wu S, Pan R, Lu J, Wu X, Xie J, Tang H and
Li X: Development and verification of a prognostic
Ferroptosis-related gene model in triple-negative breast cancer.
Front Oncol. 12:8969272022. View Article : Google Scholar : PubMed/NCBI
|
|
132
|
Zou Y, Yang A, Chen B, Deng X, Xie J, Dai
D, Zhang J, Tang H, Wu T, Zhou Z, et al: crVDAC3 alleviates
ferroptosis by impeding HSPB1 ubiquitination and confers
trastuzumab deruxtecan resistance in HER2-low breast cancer. Drug
Resist Updat. 77:1011262024. View Article : Google Scholar : PubMed/NCBI
|
|
133
|
Giordano C, Chemi F, Panza S, Barone I,
Bonofiglio D, Lanzino M, Cordella A, Campana A, Hashim A, Rizza P,
et al: Leptin as a mediator of tumor-stromal interactions promotes
breast cancer stem cell activity. Oncotarget. 7:1262–1275. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
134
|
Balaban S, Shearer RF, Lee LS, van
Geldermalsen M, Schreuder M, Shtein HC, Cairns R, Thomas KC,
Fazakerley DJ, Grewal T, et al: Adipocyte lipolysis links obesity
to breast cancer growth: Adipocyte-derived fatty acids drive breast
cancer cell proliferation and migration. Cancer Metab. 5:12017.
View Article : Google Scholar : PubMed/NCBI
|
|
135
|
He JY, Wei XH, Li SJ, Liu Y, Hu HL, Li ZZ,
Kuang XH, Wang L, Shi X, Yuan ST and Sun L: Adipocyte-derived IL-6
and leptin promote breast Cancer metastasis via upregulation of
Lysyl Hydroxylase-2 expression. Cell Commun Signal. 16:1002018.
View Article : Google Scholar : PubMed/NCBI
|
|
136
|
Koundouros N and Poulogiannis G:
Reprogramming of fatty acid metabolism in cancer. Br J Cancer.
122:4–22. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
137
|
Bobiński R, Dutka M, Pizon M, Waksmańska W
and Pielesz A: Ferroptosis, Acyl starvation, and breast cancer. Mol
Pharmacol. 103:132–144. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
138
|
Pondé NF, Zardavas D and Piccart M:
Progress in adjuvant systemic therapy for breast cancer. Nat Rev
Clin Oncol. 16:27–44. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
139
|
Bi M, Zhang Z, Jiang YZ, Xue P, Wang H,
Lai Z, Fu X, De Angelis C, Gong Y, Gao Z, et al: Enhancer
reprogramming driven by high-order assemblies of transcription
factors promotes phenotypic plasticity and breast cancer endocrine
resistance. Nat Cell Biol. 22:701–715. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
140
|
Xu Z, Wang X, Sun W, Xu F, Kou H, Hu W,
Zhang Y, Jiang Q, Tang J and Xu Y: RelB-activated GPX4 inhibits
ferroptosis and confers tamoxifen resistance in breast cancer.
Redox Biol. 68:1029522023. View Article : Google Scholar : PubMed/NCBI
|
|
141
|
He HL, Lee YE, Chen HP, Hsing CH, Chang
IW, Shiue YL, Lee SW, Hsu CT, Lin LC, Wu TF and Li CF:
Overexpression of DNAJC12 predicts poor response to neoadjuvant
concurrent chemoradiotherapy in patients with rectal cancer. Exp
Mol Pathol. 98:338–345. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
142
|
Shen M, Cao S, Long X, Xiao L, Yang L,
Zhang P, Li L, Chen F, Lei T, Gao H, et al: DNAJC12 causes breast
cancer chemotherapy resistance by repressing doxorubicin-induced
ferroptosis and apoptosis via activation of AKT. Redox Biol.
70:1030352024. View Article : Google Scholar : PubMed/NCBI
|
|
143
|
Bianchini G, Balko JM, Mayer IA, Sanders
ME and Gianni L: Triple-negative breast cancer: Challenges and
opportunities of a heterogeneous disease. Nat Rev Clin Oncol.
13:674–690. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
144
|
Denkert C, Liedtke C, Tutt A and von
Minckwitz G: Molecular alterations in triple-negative breast
cancer-the road to new treatment strategies. Lancet. 389:2430–2442.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
145
|
Xiao Y, Ma D, Zhao S, Suo C, Shi J, Xue
MZ, Ruan M, Wang H, Zhao J, Li Q, et al: Multi-Omics Profiling
reveals distinct microenvironment characterization and suggests
immune escape mechanisms of Triple-negative breast cancer. Clin
Cancer Res. 25:5002–5014. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
146
|
Yu H, Yang C, Jian L, Guo S, Chen R, Li K,
Qu F, Tao K, Fu Y, Luo F and Liu S: Sulfasalazine-induced
ferroptosis in breast cancer cells is reduced by the inhibitory
effect of estrogen receptor on the transferrin receptor. Oncol Rep.
42:826–838. 2019.PubMed/NCBI
|
|
147
|
Timmerman LA, Holton T, Yuneva M, Louie
RJ, Padró M, Daemen A, Hu M, Chan DA, Ethier SP, van ‘t Veer LJ, et
al: Glutamine sensitivity analysis identifies the xCT antiporter as
a common triple-negative breast tumor therapeutic target. Cancer
Cell. 24:450–465. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
148
|
Wang Z, Dong J, Tian W, Qiao S and Wang H:
Role of TRPV1 ion channel in cervical squamous cell carcinoma
genesis. Front Mol Biosci. 9:9802622022. View Article : Google Scholar : PubMed/NCBI
|
|
149
|
Liu Y, Li L, Yang Z, Wen D and Hu Z:
Circular RNA circACAP2 suppresses ferroptosis of cervical cancer
during malignant progression by miR-193a-5p/GPX4. J Oncol.
2022:52288742022.PubMed/NCBI
|
|
150
|
Wu P, Li C, Ye DM, Yu K, Li Y, Tang H, Xu
G, Yi S and Zhang Z: Circular RNA circEPSTI1 accelerates cervical
cancer progression via miR-375/409-3P/515-5p-SLC7A11 axis. Aging
(Albany NY). 13:4663–4673. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
151
|
Xiong J, Nie M, Fu C, Chai X, Zhang Y, He
L and Sun S: Hypoxia enhances HIF1α transcription activity by
Upregulating KDM4A and mediating H3K9me3, thus inducing ferroptosis
resistance in cervical cancer cells. Stem Cells Int.
2022:16088062022. View Article : Google Scholar : PubMed/NCBI
|
|
152
|
Wu Y, Fang B, Yang XQ, Wang L, Chen D,
Krasnykh V, Carter BZ, Morris JS and Shureiqi I: Therapeutic
molecular targeting of 15-lipoxygenase-1 in colon cancer. Mol Ther.
16:886–892. 2008. View Article : Google Scholar
|
|
153
|
Abdurahman A, Li Y, Jia SZ, Xu XW, Lin SJ,
Ouyang P, Jun He Z, Zhang ZH, Liu Q, Xu Y and Song GL: Knockdown of
the SELENOK gene induces ferroptosis in cervical cancer cells.
Metallomics. 15:mfad0192023. View Article : Google Scholar : PubMed/NCBI
|
|
154
|
Ray Chaudhuri A and Nussenzweig A: The
multifaceted roles of PARP1 in DNA repair and chromatin
remodelling. Nat Rev Mol Cell Biol. 18:610–621. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
155
|
Sánchez-Quesada C, López-Biedma A and
Gaforio JJ: Oleanolic acid, a compound present in grapes and
olives, protects against genotoxicity in human mammary epithelial
cells. Molecules. 20:13670–13688. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
156
|
Shi H, Xiong L, Yan G, Du S, Liu J and Shi
Y: Susceptibility of cervical cancer to dihydroartemisinin-induced
ferritinophagy-dependent ferroptosis. Front Mol Biosci.
10:11560622023. View Article : Google Scholar : PubMed/NCBI
|
|
157
|
Liu S, Zhang HL, Li J, Ye ZP, Du T, Li LC,
Guo YQ, Yang D, Li ZL, Cao JH, et al: Tubastatin A potently
inhibits GPX4 activity to potentiate cancer radiotherapy through
boosting ferroptosis. Redox Biol. 62:1026772023. View Article : Google Scholar : PubMed/NCBI
|
|
158
|
Lei G, Zhang Y, Koppula P, Liu X, Zhang J,
Lin SH, Ajani JA, Xiao Q, Liao Z, Wang H and Gan B: The role of
ferroptosis in ionizing radiation-induced cell death and tumor
suppression. Cell Res. 30:146–162. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
159
|
Lheureux S, Gourley C, Vergote I and Oza
AM: Epithelial ovarian cancer. Lancet. 393:1240–1253. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
160
|
Zhang J, Ouyang F, Gao A, Zeng T, Li M, Li
H, Zhou W, Gao Q, Tang X, Zhang Q, et al: ESM1 enhances fatty acid
synthesis and vascular mimicry in ovarian cancer by utilizing the
PKM2-dependent Warburg effect within the hypoxic tumor
microenvironment. Mol Cancer. 23:942024. View Article : Google Scholar : PubMed/NCBI
|
|
161
|
Fan Z, Ye M, Liu D, Zhou W, Zeng T, He S
and Li Y: Lactate drives the ESM1-SCD1 axis to inhibit the
antitumor CD8+ T-cell response by activating the Wnt/β-catenin
pathway in ovarian cancer cells and inducing cisplatin resistance.
Int Immunopharmacol. 137:1124612024. View Article : Google Scholar : PubMed/NCBI
|
|
162
|
Li YK, Gao AB, Zeng T, Liu D, Zhang QF,
Ran XM, Tang ZZ, Li Y, Liu J, Zhang T, et al: ANGPTL4 accelerates
ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis
in the tumor microenvironment by activating the JAK2/STAT3 pathway
and interacting with ESM1. J Transl Med. 22:462024. View Article : Google Scholar : PubMed/NCBI
|
|
163
|
Christie EL and Bowtell DDL: Acquired
chemotherapy resistance in ovarian cancer. Ann Oncol. 28
(Suppl_8):viii13–viii5. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
164
|
Ruan D, Wen J, Fang F, Lei Y, Zhao Z and
Miao Y: Ferroptosis in epithelial ovarian cancer: A burgeoning
target with extraordinary therapeutic potential. Cell Death Discov.
9:4342023. View Article : Google Scholar : PubMed/NCBI
|
|
165
|
Fu R, Zhao B, Chen M, Fu X, Zhang Q, Cui
Y, Fu X, Li R, Zhong G and Zhou X: Moving beyond cisplatin
resistance: mechanisms, challenges, and prospects for overcoming
recurrence in clinical cancer therapy. Med Oncol. 41:92023.
View Article : Google Scholar : PubMed/NCBI
|
|
166
|
Lv C, Qu H, Zhu W, Xu K, Xu A, Jia B, Qing
Y, Li H, Wei HJ and Zhao HY: Low-dose paclitaxel inhibits tumor
cell growth by regulating glutaminolysis in colorectal carcinoma
cells. Front Pharmacol. 8:2442017. View Article : Google Scholar : PubMed/NCBI
|
|
167
|
Wang Y, Zhao G, Condello S, Huang H,
Cardenas H, Tanner EJ, Wei J, Ji Y, Li J, Tan Y, et al: Frizzled-7
identifies platinum-tolerant ovarian cancer cells susceptible to
ferroptosis. Cancer Res. 81:384–399. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
168
|
Shi M, Zhang MJ, Yu Y, Ou R, Wang Y, Li H
and Ge RS: Curcumin derivative NL01 induces ferroptosis in ovarian
cancer cells via HCAR1/MCT1 signaling. Cell Signal. 109:1107912023.
View Article : Google Scholar : PubMed/NCBI
|
|
169
|
Cheng Q, Bao L, Li M, Chang K and Yi X:
Erastin synergizes with cisplatin via ferroptosis to inhibit
ovarian cancer growth in vitro and in vivo. J Obstet Gynaecol Res.
47:2481–2491. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
170
|
Ni M, Zhou J, Zhu Z, Xu Q, Yin Z, Wang Y,
Zheng Z and Zhao H: Shikonin and cisplatin synergistically overcome
cisplatin resistance of ovarian cancer by inducing ferroptosis via
upregulation of HMOX1 to promote Fe2+ accumulation. Phytomedicine.
112:1547012023. View Article : Google Scholar : PubMed/NCBI
|
|
171
|
Krishnakumar R and Kraus WL: The PARP side
of the nucleus: Molecular actions, physiological outcomes, and
clinical targets. Mol Cell. 39:8–24. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
172
|
Gibson BA and Kraus WL: New insights into
the molecular and cellular functions of poly(ADP-ribose) and PARPs.
Nat Rev Mol Cell Biol. 13:411–424. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
173
|
Audeh MW, Carmichael J, Penson RT,
Friedlander M, Powell B, Bell-McGuinn KM, Scott C, Weitzel JN,
Oaknin A, Loman N, et al: Oral poly(ADP-ribose) polymerase
inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and
recurrent ovarian cancer: A proof-of-concept trial. Lancet.
376:245–251. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
174
|
Alsop K, Fereday S, Meldrum C, deFazio A,
Emmanuel C, George J, Dobrovic A, Birrer MJ, Webb PM, Stewart C, et
al: BRCA mutation frequency and patterns of treatment response in
BRCA mutation-positive women with ovarian cancer: A report from the
Australian Ovarian Cancer Study Group. J Clin Oncol. 30:2654–2663.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
175
|
Hong T, Lei G, Chen X, Li H, Zhang X, Wu
N, Zhao Y, Zhang Y and Wang J: PARP inhibition promotes ferroptosis
via repressing SLC7A11 and synergizes with ferroptosis inducers in
BRCA-proficient ovarian cancer. Redox Biol. 42:1019282021.
View Article : Google Scholar : PubMed/NCBI
|
|
176
|
Tang S, Shen Y, Wei X, Shen Z, Lu W and Xu
J: Olaparib synergizes with arsenic trioxide by promoting apoptosis
and ferroptosis in platinum-resistant ovarian cancer. Cell Death
Dis. 13:8262022. View Article : Google Scholar : PubMed/NCBI
|
|
177
|
Sung H, Ferlay J, Siegel RL, Laversanne M,
Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020:
GLOBOCAN estimates of incidence and mortality worldwide for 36
cancers in 185 countries. CA Cancer J Clin. 71:209–249. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
178
|
Fang X, Zhang T and Chen Z: Solute carrier
family 7 member 11 (SLC7A11) is a potential prognostic biomarker in
uterine corpus endometrial carcinoma. Int J Gen Med. 16:481–497.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
179
|
Marshall AD, van Geldermalsen M, Otte NJ,
Lum T, Vellozzi M, Thoeng A, Pang A, Nagarajah R, Zhang B, Wang Q,
et al: ASCT2 regulates glutamine uptake and cell growth in
endometrial carcinoma. Oncogenesis. 6:e3672017. View Article : Google Scholar : PubMed/NCBI
|
|
180
|
Liu X, Olszewski K, Zhang Y, Lim EW, Shi
J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, et al: Cystine
transporter regulation of pentose phosphate pathway dependency and
disulfide stress exposes a targetable metabolic vulnerability in
cancer. Nat Cell Biol. 22:476–486. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
181
|
Byrne FL, Poon IK, Modesitt SC, Tomsig JL,
Chow JD, Healy ME, Baker WD, Atkins KA, Lancaster JM, Marchion DC,
et al: Metabolic vulnerabilities in endometrial cancer. Cancer Res.
74:5832–5845. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
182
|
Han X, Ren C, Yang T, Qiao P, Wang L,
Jiang A, Meng Y, Liu Z, Du Y and Yu Z: Negative regulation of
AMPKα1 by PIM2 promotes aerobic glycolysis and tumorigenesis in
endometrial cancer. Oncogene. 38:6537–6549. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
183
|
Cheng H, Jiang XY, Zheng RR, Zuo SJ, Zhao
LP, Fan GL, Xie BR, Yu XY, Li SY and Zhang XZ: A biomimetic cascade
nanoreactor for tumor targeted starvation therapy-amplified
chemotherapy. Biomaterials. 195:75–85. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
184
|
Yu S, Chen Z, Zeng X, Chen X and Gu Z:
Advances in nanomedicine for cancer starvation therapy.
Theranostics. 9:8026–8047. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
185
|
Murakami H, Hayashi M, Terada S and
Ohmichi M: Medroxyprogesterone acetate-resistant endometrial cancer
cells are susceptible to ferroptosis inducers. Life Sci.
325:1217532023. View Article : Google Scholar : PubMed/NCBI
|
|
186
|
Zhang YY, Ni ZJ, Elam E, Zhang F, Thakur
K, Wang S, Zhang JG and Wei ZJ: Juglone, a novel activator of
ferroptosis, induces cell death in endometrial carcinoma Ishikawa
cells. Food Funct. 12:4947–4959. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
187
|
Hua Y, Yang S, Zhang Y, Li J, Wang M,
Yeerkenbieke P, Liao Q and Liu Q: Modulating ferroptosis
sensitivity: Environmental and cellular targets within the tumor
microenvironment. J Exp Clin Cancer Res. 43:192024. View Article : Google Scholar : PubMed/NCBI
|
|
188
|
Hu Y, Wang H and Liu Y: NETosis: Sculpting
tumor metastasis and immunotherapy. Immunol Rev. 321:263–279. 2024.
View Article : Google Scholar : PubMed/NCBI
|
|
189
|
Zhang H, Liu J, Zhou Y, Qu M, Wang Y, Guo
K, Shen R, Sun Z, Cata JP, Yang S, et al: Neutrophil extracellular
traps mediate m6A modification and regulates sepsis-associated
acute lung injury by activating ferroptosis in alveolar epithelial
cells. Int J Biol Sci. 18:3337–3357. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
190
|
Chu C, Wang X, Yang C, Chen F, Shi L, Xu
W, Wang K, Liu B, Wang C, Sun D and Ding W: Neutrophil
extracellular traps drive intestinal microvascular endothelial
ferroptosis by impairing Fundc1-dependent mitophagy. Redox Biol.
67:1029062023. View Article : Google Scholar : PubMed/NCBI
|
|
191
|
Medlock AE, Hixon JC, Bhuiyan T and Cobine
PA: Prime real estate: Metals, cofactors and MICOS. Front Cell Dev
Biol. 10:8923252022. View Article : Google Scholar : PubMed/NCBI
|
|
192
|
Xie J, Yang Y, Gao Y and He J:
Cuproptosis: Mechanisms and links with cancers. Mol Cancer.
22:462023. View Article : Google Scholar : PubMed/NCBI
|
|
193
|
Wang W, Lu K, Jiang X, Wei Q, Zhu L, Wang
X, Jin H and Feng L: Ferroptosis inducers enhanced cuproptosis
induced by copper ionophores in primary liver cancer. J Exp Clin
Cancer Res. 42:1422023. View Article : Google Scholar : PubMed/NCBI
|
|
194
|
Li Y, Du Y, Zhou Y, Chen Q, Luo Z, Ren Y,
Chen X and Chen G: Iron and copper: Critical executioners of
ferroptosis, cuproptosis and other forms of cell death. Cell Commun
Signal. 21:3272023. View Article : Google Scholar : PubMed/NCBI
|
|
195
|
Liu T, Liu W, Zhang M, Yu W, Gao F, Li C,
Wang SB, Feng J and Zhang XZ: Ferrous-supply-regeneration
nanoengineering for cancer-cell-specific ferroptosis in combination
with imaging-guided photodynamic therapy. ACS Nano. 12:12181–12192.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
196
|
Dixon SJ, Patel DN, Welsch M, Skouta R,
Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS
and Stockwell BR: Pharmacological inhibition of cystine-glutamate
exchange induces endoplasmic reticulum stress and ferroptosis.
Elife. 3:e025232014. View Article : Google Scholar : PubMed/NCBI
|
|
197
|
Liang C, Zhang X, Yang M and Dong X:
Recent progress in ferroptosis inducers for cancer therapy. Adv
Mater. 31:e19041972019. View Article : Google Scholar : PubMed/NCBI
|
|
198
|
Yang J, Jia Z, Zhang J, Pan X, Wei Y, Ma
S, Yang N, Liu Z and Shen Q: Metabolic intervention nanoparticles
for triple-negative breast cancer therapy via overcoming
FSP1-mediated ferroptosis resistance. Adv Healthc Mater.
11:e21027992022. View Article : Google Scholar : PubMed/NCBI
|
|
199
|
Radadiya PS, Thornton MM, Puri RV,
Yerrathota S, Dinh-Phan J, Magenheimer B, Subramaniam D, Tran PV,
Zhu H, Bolisetty S, et al: Ciclopirox olamine induces
ferritinophagy and reduces cyst burden in polycystic kidney
disease. JCI Insight. 6:e1412992021. View Article : Google Scholar : PubMed/NCBI
|
|
200
|
Yao X, Zhang Y, Hao J, Duan HQ, Zhao CX,
Sun C, Li B, Fan BY, Wang X, Li WX, et al: Deferoxamine promotes
recovery of traumatic spinal cord injury by inhibiting ferroptosis.
Neural Regen Res. 14:532–541. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
201
|
Zheng H, Jiang J, Xu S, Liu W, Xie Q, Cai
X, Zhang J, Liu S and Li R: Nanoparticle-induced ferroptosis:
Detection methods, mechanisms and applications. Nanoscale.
13:2266–2285. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
202
|
Brown CW, Amante JJ, Chhoy P, Elaimy AL,
Liu H, Zhu LJ, Baer CE, Dixon SJ and Mercurio AM: Prominin2 drives
ferroptosis resistance by stimulating iron export. Dev Cell.
51:575–586.e4. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
203
|
Wu H and Liu A: Long non-coding RNA NEAT1
regulates ferroptosis sensitivity in non-small-cell lung cancer. J
Int Med Res. 49:3000605219961832021. View Article : Google Scholar : PubMed/NCBI
|
|
204
|
Alim I, Caulfield JT, Chen Y, Swarup V,
Geschwind DH, Ivanova E, Seravalli J, Ai Y, Sansing LH, Ste Marie
EJ, et al: Selenium drives a transcriptional adaptive program to
block ferroptosis and treat stroke. Cell. 177:1262–1279.e25. 2019.
View Article : Google Scholar : PubMed/NCBI
|
