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Review Open Access

Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review)

  • Authors:
    • Xinlong Wang
    • Dong Zhao
    • Ershu Zhao
    • Yanan Ge
    • Fei Cai
    • Yidan Xi
    • Jiatong Li
    • Xuefei Liu
    • Zhendong Zheng
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, General Hospital of Northern Theater Command, Shenyang, Liaoning 110000, P.R. China, Department of Periodontics, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong 510000, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 62
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    Published online on: April 11, 2025
       https://doi.org/10.3892/or.2025.8895
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Abstract

This article examines the multifaceted roles of the S100P gene in pan‑cancer, with the aim of exploring its biological functions and related mechanisms in depth. S100P is a small calcium‑binding protein that recent studies have identified as playing a significant role in the occurrence and progression of various cancers. As research on cancer biomarkers advances, the relationship between S100P expression levels and cancer prognosis, metastasis and invasiveness has garnered increasing attention. However, the specific mechanisms underlying the role of S100P in different cancer types remain elusive and related research is still in the exploratory phase. Therefore, this review systematically summarizes the biological functions of S100P, clarifying its signaling pathways and regulatory mechanisms. This work provides new insights and strategies for targeted therapy and establishes a theoretical basis for subsequent clinical applications. Through this summary, the present review aims to enhance personalized treatment approaches for S100P‑related cancers and strengthen future explorations of S100P.
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Copy and paste a formatted citation
Spandidos Publications style
Wang X, Zhao D, Zhao E, Ge Y, Cai F, Xi Y, Li J, Liu X and Zheng Z: Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review). Oncol Rep 53: 62, 2025.
APA
Wang, X., Zhao, D., Zhao, E., Ge, Y., Cai, F., Xi, Y. ... Zheng, Z. (2025). Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review). Oncology Reports, 53, 62. https://doi.org/10.3892/or.2025.8895
MLA
Wang, X., Zhao, D., Zhao, E., Ge, Y., Cai, F., Xi, Y., Li, J., Liu, X., Zheng, Z."Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review)". Oncology Reports 53.6 (2025): 62.
Chicago
Wang, X., Zhao, D., Zhao, E., Ge, Y., Cai, F., Xi, Y., Li, J., Liu, X., Zheng, Z."Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review)". Oncology Reports 53, no. 6 (2025): 62. https://doi.org/10.3892/or.2025.8895
Copy and paste a formatted citation
x
Spandidos Publications style
Wang X, Zhao D, Zhao E, Ge Y, Cai F, Xi Y, Li J, Liu X and Zheng Z: Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review). Oncol Rep 53: 62, 2025.
APA
Wang, X., Zhao, D., Zhao, E., Ge, Y., Cai, F., Xi, Y. ... Zheng, Z. (2025). Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review). Oncology Reports, 53, 62. https://doi.org/10.3892/or.2025.8895
MLA
Wang, X., Zhao, D., Zhao, E., Ge, Y., Cai, F., Xi, Y., Li, J., Liu, X., Zheng, Z."Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review)". Oncology Reports 53.6 (2025): 62.
Chicago
Wang, X., Zhao, D., Zhao, E., Ge, Y., Cai, F., Xi, Y., Li, J., Liu, X., Zheng, Z."Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review)". Oncology Reports 53, no. 6 (2025): 62. https://doi.org/10.3892/or.2025.8895
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