[Expression of Concern] Downregulation of miR‑145 contributes to lung adenocarcinoma cell growth to form brain metastases

Zhao,Chunyang; Xu,Yan; Zhang,Yongqiang; Tan,Weiwei; Xue,Jianxin; Yang,Zongze; Zhang,You; Lu,You; Hu,Xun

doi:10.3892/or.2025.8991

December-2025 Volume 54 Issue 6

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December-2025 Volume 54 Issue 6

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Expression of Concern Open Access

[Expression of Concern] Downregulation of miR‑145 contributes to lung adenocarcinoma cell growth to form brain metastases

Authors:
- Chunyang Zhao
- Yan Xu
- Yongqiang Zhang
- Weiwei Tan
- Jianxin Xue
- Zongze Yang
- You Zhang
- You Lu
- Xun Hu
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Affiliations: Biorepository, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China, Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China

Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 158
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Published online on: September 18, 2025

https://doi.org/10.3892/or.2025.8991
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Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the cell migration and invasion assay experiments shown in Fig. 4, the ‘Mock’ data panel in Fig. 4A‑a (A549 cell line, migration assay) was apparently identical to the ‘Mock’ data panel in Fig. 4B‑b (SPC‑A1 cell line, invasion assay), even though the reported experimental conditions were different. The authors were contacted by the Editorial Office to offer an explanation for this apparent data duplication; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Oncology Reports 30: 2027‑2034, 2013; DOI: 10.3892/or.2013.2728]

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