[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma

You,Lei; Ren,Xiaoxia; Du,Yongxing; Zhao,Wenjing; Cui,Ming; Chen,Ge; Zhao,Yupei

doi:10.3892/or.2026.9092

May-2026 Volume 55 Issue 5

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May-2026 Volume 55 Issue 5

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Expression of Concern Open Access

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma

Authors:
- Lei You
- Xiaoxia Ren
- Yongxing Du
- Wenjing Zhao
- Ming Cui
- Ge Chen
- Yupei Zhao
View Affiliations / Copyright

Affiliations: Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China

Copyright: © You et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 87
|
Published online on: March 5, 2026

https://doi.org/10.3892/or.2026.9092
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Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the histological images shown in Fig. 2B on p. 3416, the ῾Caerulein 7 days’ and ‘Caerulein 14 days’ panels showed an overlapping section, with the image also being magnified in the latter panel relative to the first. In addition, the immunohistochemical images shown for the ‘c‑Fos/PK, caerulein+U0126’ experiment in Fig. 3A and the ‘c‑Fos/Control/Caerulein 7 days’ experiment in Fig. 4A were identical, suggesting that at least one of these figures had been assembled incorrectly. The authors have been contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of these potential problems while the Editorial Office continues to investigate this matter further. [Oncology Reports 36: 3413‑3420, 2016; DOI: 10.3892/or.2016.5169]

Oncol Rep 36: [Related article:] 3413–3420, 2016; DOI: 10.3892/or.2016.5169

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the histological images shown in Fig. 2B on p. 3416, the ‘Caerulein 7 days’ and ‘Caerulein 14 days’ panels showed an overlapping section, with the image also being magnified in the latter panel relative to the first. In addition, the immunohistochemical images shown for the ‘c-Fos/PK, caerulein+U0126’ experiment in Fig. 3A and the ‘c-Fos/Control/Caerulein 7 days’ experiment in Fig. 4A were identical, suggesting that at least one of these figures had been assembled incorrectly.

The authors have been contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of these potential problems while the Editorial Office continues to investigate this matter further.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma

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Abstract

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