Difference in histological activity of non-tumorous liver tissue between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma without cirrhosis

  • Authors:
    • T Muro
    • K Nakata
    • H Kamito
    • Y Kato
    • K Nakao
    • K Toriyama
    • S Tsuruta
    • Y Shibata
    • T Arima
    • S Nagataki
  • View Affiliations

  • Published online on: January 1, 1996     https://doi.org/10.3892/or.3.1.87
  • Pages: 87-89
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Abstract

To elucidate the difference in the liver carcinogenetic process during hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, non-tumorous liver tissues obtained from 10 patients who developed HBV-associated hepatocellular carcinoma (HCC) without cirrhosis were compared with those obtained from 26 patients who developed HCV-associated HCC without cirrhosis. The extent of fibrosis was similar in both groups. In contrast, necroinflammatory activities were significantly higher in patients with HCV than in patients with HBV. These results indicate that ongoing liver inflammation mediates the hepatocarcinogenesis more pronouncedly in HCV infection than in HBV infection.

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January 1996
Volume 3 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Muro T, Nakata K, Kamito H, Kato Y, Nakao K, Toriyama K, Tsuruta S, Shibata Y, Arima T, Nagataki S, Nagataki S, et al: Difference in histological activity of non-tumorous liver tissue between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma without cirrhosis. Oncol Rep 3: 87-89, 1996
APA
Muro, T., Nakata, K., Kamito, H., Kato, Y., Nakao, K., Toriyama, K. ... Nagataki, S. (1996). Difference in histological activity of non-tumorous liver tissue between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma without cirrhosis. Oncology Reports, 3, 87-89. https://doi.org/10.3892/or.3.1.87
MLA
Muro, T., Nakata, K., Kamito, H., Kato, Y., Nakao, K., Toriyama, K., Tsuruta, S., Shibata, Y., Arima, T., Nagataki, S."Difference in histological activity of non-tumorous liver tissue between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma without cirrhosis". Oncology Reports 3.1 (1996): 87-89.
Chicago
Muro, T., Nakata, K., Kamito, H., Kato, Y., Nakao, K., Toriyama, K., Tsuruta, S., Shibata, Y., Arima, T., Nagataki, S."Difference in histological activity of non-tumorous liver tissue between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma without cirrhosis". Oncology Reports 3, no. 1 (1996): 87-89. https://doi.org/10.3892/or.3.1.87