Expression of GalCer sulfotransferase by human uterine endometrial carcinoma cell lines

  • Authors:
    • K Kamei
    • K Kubushiro
    • M Mikami
    • K Tsukazaki
    • S Nozawa
    • M Iwamori
  • View Affiliations

  • Published online on: July 1, 1996     https://doi.org/10.3892/or.3.4.657
  • Pages: 657-660
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Abstract

We investigated the expression of sulfoglycolipids in several gynecological cancer cell lines by metabolic labeling with S-35-sulfate as well as the activity of GalCer sulfotransferase (ST) and arylsulfatase A (ASA), enzymes which are responsible for the synthesis and degradation of sulfoglycolipids. The endometrial carcinoma cell lines expressed sulfoglycolipids and showed ST activity, indicating that increased synthesis of sulfoglycolipids due to elevated ST activity is a characteristic of endometrial carcinoma that distinguishes it from other carcinomas. These cell lines could provide a useful model for studying the functions of sulfoglycolipids as well as biological properties of ST in cancer cells.

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July 1996
Volume 3 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Kamei K, Kubushiro K, Mikami M, Tsukazaki K, Nozawa S and Iwamori M: Expression of GalCer sulfotransferase by human uterine endometrial carcinoma cell lines. Oncol Rep 3: 657-660, 1996
APA
Kamei, K., Kubushiro, K., Mikami, M., Tsukazaki, K., Nozawa, S., & Iwamori, M. (1996). Expression of GalCer sulfotransferase by human uterine endometrial carcinoma cell lines. Oncology Reports, 3, 657-660. https://doi.org/10.3892/or.3.4.657
MLA
Kamei, K., Kubushiro, K., Mikami, M., Tsukazaki, K., Nozawa, S., Iwamori, M."Expression of GalCer sulfotransferase by human uterine endometrial carcinoma cell lines". Oncology Reports 3.4 (1996): 657-660.
Chicago
Kamei, K., Kubushiro, K., Mikami, M., Tsukazaki, K., Nozawa, S., Iwamori, M."Expression of GalCer sulfotransferase by human uterine endometrial carcinoma cell lines". Oncology Reports 3, no. 4 (1996): 657-660. https://doi.org/10.3892/or.3.4.657