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Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite

  • Authors:
    • M Imamura
    • T Seki
    • K Kunieda
    • S Nakatani
    • T Tamai
    • K Inoue
    • K Nagata
    • Y Tanaka
    • Y Obiya
    • K Harada

  • View Affiliations

  • Published online on: November 1, 1996     https://doi.org/10.3892/or.3.6.1017
  • Pages: 1017-1019
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

We have already reported the antitumour effect of hydroxyapatite (HAP) containing anticancer drugs. In this study, we found an increased temperature effect around HAP particle(s) in an agar phantom in comparison with other areas when a Thermotron-RF8 (RF generator) was used for heating. Furthermore, it was revealed that the quantity of doxorubicin hydrochloride (DOX) released from HAP containing the drug (DOX-HAP complex) was increased by raising the temperature. These results indicated that the antitumor effect of the DOX-HAP complex + hyperthermia system was greater than that of either the DOX-HAP complex or hyperthermia system alone.

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November 1996
Volume 3 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • CiteScore: 8.4
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  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
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Spandidos Publications style
Imamura M, Seki T, Kunieda K, Nakatani S, Tamai T, Inoue K, Nagata K, Tanaka Y, Obiya Y, Harada K, Harada K, et al: Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite. Oncol Rep 3: 1017-1019, 1996
APA
Imamura, M., Seki, T., Kunieda, K., Nakatani, S., Tamai, T., Inoue, K. ... Harada, K. (1996). Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite. Oncology Reports, 3, 1017-1019. https://doi.org/10.3892/or.3.6.1017
MLA
Imamura, M., Seki, T., Kunieda, K., Nakatani, S., Tamai, T., Inoue, K., Nagata, K., Tanaka, Y., Obiya, Y., Harada, K."Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite". Oncology Reports 3.6 (1996): 1017-1019.
Chicago
Imamura, M., Seki, T., Kunieda, K., Nakatani, S., Tamai, T., Inoue, K., Nagata, K., Tanaka, Y., Obiya, Y., Harada, K."Potential applicability of clinical hyperthermia using a Thermotron-RF8 as assessed from thermal distribution in an agar phantom containing hydroxyapatite". Oncology Reports 3, no. 6 (1996): 1017-1019. https://doi.org/10.3892/or.3.6.1017