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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 1996 Volume 3 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November 1996 Volume 3 Issue 6

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Article

Adhesion molecules involved in pleural dissemination of esophageal cancer cells

  • Authors:
    • T Nakashio
    • T Narita
    • N Kimura
    • S Akiyama
    • Y Kasai
    • K Ito
    • H Takagi
    • R Kannagi

  • View Affiliations / Copyright

    Affiliations: AICHI CANC CTR, LAB EXPT PATHOL, RES INST, CHIKUSA KU, NAGOYA, AICHI 464, JAPAN. NAGOYA UNIV, SCH MED, DEPT SURG 2, SHOWA KU, NAGOYA, AICHI 466, JAPAN.
  • Pages: 1063-1066
    |
    Published online on: November 1, 1996
       https://doi.org/10.3892/or.3.6.1063
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Abstract

Pleural dissemination is a common cause of recurrence after surgery of patients with esophageal cancer. Very little is known about the biochemical processes involved in the initial attachment of cancer cells to pleural mesothelial cells. The authors conducted in vitro and in vivo studies to assess the role of adhesion molecules in this process, using 2 cell lines derived from human esophageal cancer. TE-1 cells, which pronouncedly express CD44H, adhered to the monolayers of mesothelial cells more firmly than T.Tn cells. On the other hand, the adhesion of TE-I cells to mesothelial cells was markedly inhibited by antibodies to CD44H or the beta(1) integrin subunit, and more strongly blocked by using a combination of the two antibodies. These antibodies inhibited the dissemination of TE-1 cells in the pleural cavity of nude mice. The findings suggest that CD44 and integrin play important roles in the initial attachment of esophageal cancer cells to mesothelial cells.

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Copy and paste a formatted citation
Spandidos Publications style
Nakashio T, Narita T, Kimura N, Akiyama S, Kasai Y, Ito K, Takagi H and Kannagi R: Adhesion molecules involved in pleural dissemination of esophageal cancer cells. Oncol Rep 3: 1063-1066, 1996.
APA
Nakashio, T., Narita, T., Kimura, N., Akiyama, S., Kasai, Y., Ito, K. ... Kannagi, R. (1996). Adhesion molecules involved in pleural dissemination of esophageal cancer cells. Oncology Reports, 3, 1063-1066. https://doi.org/10.3892/or.3.6.1063
MLA
Nakashio, T., Narita, T., Kimura, N., Akiyama, S., Kasai, Y., Ito, K., Takagi, H., Kannagi, R."Adhesion molecules involved in pleural dissemination of esophageal cancer cells". Oncology Reports 3.6 (1996): 1063-1066.
Chicago
Nakashio, T., Narita, T., Kimura, N., Akiyama, S., Kasai, Y., Ito, K., Takagi, H., Kannagi, R."Adhesion molecules involved in pleural dissemination of esophageal cancer cells". Oncology Reports 3, no. 6 (1996): 1063-1066. https://doi.org/10.3892/or.3.6.1063
Copy and paste a formatted citation
x
Spandidos Publications style
Nakashio T, Narita T, Kimura N, Akiyama S, Kasai Y, Ito K, Takagi H and Kannagi R: Adhesion molecules involved in pleural dissemination of esophageal cancer cells. Oncol Rep 3: 1063-1066, 1996.
APA
Nakashio, T., Narita, T., Kimura, N., Akiyama, S., Kasai, Y., Ito, K. ... Kannagi, R. (1996). Adhesion molecules involved in pleural dissemination of esophageal cancer cells. Oncology Reports, 3, 1063-1066. https://doi.org/10.3892/or.3.6.1063
MLA
Nakashio, T., Narita, T., Kimura, N., Akiyama, S., Kasai, Y., Ito, K., Takagi, H., Kannagi, R."Adhesion molecules involved in pleural dissemination of esophageal cancer cells". Oncology Reports 3.6 (1996): 1063-1066.
Chicago
Nakashio, T., Narita, T., Kimura, N., Akiyama, S., Kasai, Y., Ito, K., Takagi, H., Kannagi, R."Adhesion molecules involved in pleural dissemination of esophageal cancer cells". Oncology Reports 3, no. 6 (1996): 1063-1066. https://doi.org/10.3892/or.3.6.1063
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