Relation between CA125 levels and second-look operation for ovarian cancer

  • Authors:
    • H Nishimura
    • Y Kiyozuka
    • K Imamura
    • N Ohkura
    • F Murakami
    • M Yakushiji
  • View Affiliations

  • Published online on: January 1, 1997     https://doi.org/10.3892/or.4.1.89
  • Pages: 89-92
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

We investigated the relationship between the serum level of CA125 before a second-look operation (SLO) and SLO findings in 196 patients with adenocarcinoma of the ovary. SLO findings were positive in 38 (19.4%) of 196 patients. The positive rate tended to increase with the clinical stage, but SLO findings were positive even in a patient with stage Ia disease. The pre-SLO serum level of CA125 was positive in 11 patients before SLO, SLO findings were positive in 8 of these 11 patients. The highest diagnostic accuracy (37.9%) for the pre-SLO serum level of CA125 was obtained at a cut-off value of 11 U/ml. Our findings suggest that a positive pre-SLO serum level of CA125 does not necessarily indicate tumor positivity. In addition, we suggest that the cut-off value for prediction of SLO findings should be below 35 U/ml, which is a commonly used cut-off value.

Related Articles

Journal Cover

January 1997
Volume 4 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Nishimura H, Kiyozuka Y, Imamura K, Ohkura N, Murakami F and Yakushiji M: Relation between CA125 levels and second-look operation for ovarian cancer. Oncol Rep 4: 89-92, 1997
APA
Nishimura, H., Kiyozuka, Y., Imamura, K., Ohkura, N., Murakami, F., & Yakushiji, M. (1997). Relation between CA125 levels and second-look operation for ovarian cancer. Oncology Reports, 4, 89-92. https://doi.org/10.3892/or.4.1.89
MLA
Nishimura, H., Kiyozuka, Y., Imamura, K., Ohkura, N., Murakami, F., Yakushiji, M."Relation between CA125 levels and second-look operation for ovarian cancer". Oncology Reports 4.1 (1997): 89-92.
Chicago
Nishimura, H., Kiyozuka, Y., Imamura, K., Ohkura, N., Murakami, F., Yakushiji, M."Relation between CA125 levels and second-look operation for ovarian cancer". Oncology Reports 4, no. 1 (1997): 89-92. https://doi.org/10.3892/or.4.1.89