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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
March 1997 Volume 4 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March 1997 Volume 4 Issue 2

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Article

Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways

  • Authors:
    • G Bauer
  • View Affiliations / Copyright

    Affiliations: Affliations not specified
  • Pages: 273-275
    |
    Published online on: March 1, 1997
       https://doi.org/10.3892/or.4.2.273
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Abstract

Papillomavirus infection interferes with four distinct and dominant levels of intra- and intercellular control of oncogenesis, three of which are based on the induction of apoptosis. Papillomaviruses cause abrogation of the cellular senescence program and interfere with p53-dependent DNA repair or apoptosis triggered by DNA damage. As a result, spontaneous or induced mutations are not eradicated and the transformed state may be established through oncogene activation and tumor suppressor gene inactivation. The interference of papillomaviruses with a recently described p53-independent intercellular control step, in which nontransformed cells induce apoptosis specifically in their transformed neighbouring cells, allows survival of papillomavirus-expressing transformed cells. Finally, p53-dependent hypoxia-triggered apoptosis in microtumors may be overcome by papillomaviruses and thus lead to efficient and rapid tumor progression.

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Copy and paste a formatted citation
Spandidos Publications style
Bauer G: Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways. Oncol Rep 4: 273-275, 1997.
APA
Bauer, G. (1997). Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways. Oncology Reports, 4, 273-275. https://doi.org/10.3892/or.4.2.273
MLA
Bauer, G."Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways". Oncology Reports 4.2 (1997): 273-275.
Chicago
Bauer, G."Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways". Oncology Reports 4, no. 2 (1997): 273-275. https://doi.org/10.3892/or.4.2.273
Copy and paste a formatted citation
x
Spandidos Publications style
Bauer G: Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways. Oncol Rep 4: 273-275, 1997.
APA
Bauer, G. (1997). Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways. Oncology Reports, 4, 273-275. https://doi.org/10.3892/or.4.2.273
MLA
Bauer, G."Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways". Oncology Reports 4.2 (1997): 273-275.
Chicago
Bauer, G."Interference of papilloma viruses with p53-dependent and -independent apoptotic pathways". Oncology Reports 4, no. 2 (1997): 273-275. https://doi.org/10.3892/or.4.2.273
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