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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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September 1997 Volume 4 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 1997 Volume 4 Issue 5

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Article

Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients

  • Authors:
    • O Merimsky
    • F Kovner
    • S Chaitchik
    • M Inbar

  • View Affiliations / Copyright

    Affiliations: TEL AVIV UNIV,SACKLER FAC MED,IL-69978 TEL AVIV,ISRAEL.
  • Pages: 1093-1097
    |
    Published online on: September 1, 1997
       https://doi.org/10.3892/or.4.5.1093
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Abstract

In a prospective open-study we evaluated the combination of radiation therapy and adjuvant 5-FU plus levamisole in controlling Modified Astler-Coller (MAC) B2 or C rectal cancer following a curative-intended surgery. Sixty-four consecutive rectal cancer patients were treated by adjuvant radiation therapy (Linac 8 MV, 50-50.4 Gy to an isocentric pelvis brick volume in 5 fractions per week each of 1.8-2 Gy), and 12 monthly courses of 5-fluorouracil (375 mg/m(2)/day for 5 consecutive days) plus levamisole (50 mg t.i.d. for 3 days). Within a median follow-up period of 36 months, 19 patients (29.6%) experienced relapses. The 3-year-DFS of MAC B2 patients was 82%, compared with 60% in MAC C. Early radiation treatment was not associated with a higher proportion of relapses, while late radiation therapy initiation was associated with a significantly higher proportion of relapses. Early radiation therapy, not later than following the 2nd to 4th course of chemotherapy, is associated with the more acceptable proportion of relapses.

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Copy and paste a formatted citation
Spandidos Publications style
Merimsky O, Kovner F, Chaitchik S and Inbar M: Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients. Oncol Rep 4: 1093-1097, 1997.
APA
Merimsky, O., Kovner, F., Chaitchik, S., & Inbar, M. (1997). Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients. Oncology Reports, 4, 1093-1097. https://doi.org/10.3892/or.4.5.1093
MLA
Merimsky, O., Kovner, F., Chaitchik, S., Inbar, M."Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients". Oncology Reports 4.5 (1997): 1093-1097.
Chicago
Merimsky, O., Kovner, F., Chaitchik, S., Inbar, M."Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients". Oncology Reports 4, no. 5 (1997): 1093-1097. https://doi.org/10.3892/or.4.5.1093
Copy and paste a formatted citation
x
Spandidos Publications style
Merimsky O, Kovner F, Chaitchik S and Inbar M: Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients. Oncol Rep 4: 1093-1097, 1997.
APA
Merimsky, O., Kovner, F., Chaitchik, S., & Inbar, M. (1997). Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients. Oncology Reports, 4, 1093-1097. https://doi.org/10.3892/or.4.5.1093
MLA
Merimsky, O., Kovner, F., Chaitchik, S., Inbar, M."Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients". Oncology Reports 4.5 (1997): 1093-1097.
Chicago
Merimsky, O., Kovner, F., Chaitchik, S., Inbar, M."Postoperative irradiation combined with chemotherapy for high-risk rectal cancer patients". Oncology Reports 4, no. 5 (1997): 1093-1097. https://doi.org/10.3892/or.4.5.1093
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