Prostatic carcinosarcoma

Petrone,U; Marascia,G; Tucci,C; Petrone,D; Gaspari,G; Angelucci,D; Iacobelli,S

doi:10.3892/or.4.6.1169

Prostatic carcinosarcoma

Authors:
- U Petrone
- G Marascia
- C Tucci
- D Petrone
- G Gaspari
- D Angelucci
- S Iacobelli
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Affiliations: AZIENDA USL CHIETI,DIV SURG NEPHROL,CHIETI,ITALY. AZIENDA USL CHIETI,DEPT PATHOL,CHIETI,ITALY. UNIV GD ANNUNZIO,DEPT ONCOL,I-66013 CHIETI,ITALY. UNIV GD ANNUNZIO,DEPT NEUROSCI,I-66013 CHIETI,ITALY.
Published online on: November 1, 1997 https://doi.org/10.3892/or.4.6.1169
Pages: 1169-1170

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Abstract

A unique case of carcinosarcoma of the prostate in a 66-year old man is presented. The patient underwent a total prostatectomy under the diagnosis of prostatic carcinoma. Despite adjuvant radiotherapy, the patient died about 3 months after the operation. The surgically resected primary tumor was composed of two histologically distinct elements, an adenocarcinoma and sarcoma with various mesodermal components. These elements were intimately intermingled and transitional forms were often noted. The sarcomatous portion contained areas of chondromatous differentiation. The pathogenesis of this complex neoplasm is discussed.