Does smoking or family history influence the prognosis of patients with non-small cell lung cancer?

  • Authors:
    • I Sekine
    • N Abe
    • S Tsugane
    • K Nagai
    • K Suzuki
    • T Kodama
    • Y Nishiwaki
    • T Ogura
    • H Esumi
  • View Affiliations

  • Published online on: November 1, 1997     https://doi.org/10.3892/or.4.6.1221
  • Pages: 1221-1227
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Abstract

The prognostic significance of pack-years smoked (PY) and family history of cancer (FH) was studied using the Cox proportional hazard model in 970 patients with non-small cell lung cancer. PY influenced survival only in women after other variables were adjusted [Hazard ratio (HR): 1.75 (1.45-2.11)]. FH also influenced survival with marginal significance in women with stage I disease [HR: 2.17 (0.89-5.29), p=0.088]. Furthermore, these two factors operated additively in women [HR for patients with both smoking and family histories over those without either: 2.25 (1.18-4.26)], but not in men.

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November 1997
Volume 4 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Sekine I, Abe N, Tsugane S, Nagai K, Suzuki K, Kodama T, Nishiwaki Y, Ogura T and Esumi H: Does smoking or family history influence the prognosis of patients with non-small cell lung cancer?. Oncol Rep 4: 1221-1227, 1997
APA
Sekine, I., Abe, N., Tsugane, S., Nagai, K., Suzuki, K., Kodama, T. ... Esumi, H. (1997). Does smoking or family history influence the prognosis of patients with non-small cell lung cancer?. Oncology Reports, 4, 1221-1227. https://doi.org/10.3892/or.4.6.1221
MLA
Sekine, I., Abe, N., Tsugane, S., Nagai, K., Suzuki, K., Kodama, T., Nishiwaki, Y., Ogura, T., Esumi, H."Does smoking or family history influence the prognosis of patients with non-small cell lung cancer?". Oncology Reports 4.6 (1997): 1221-1227.
Chicago
Sekine, I., Abe, N., Tsugane, S., Nagai, K., Suzuki, K., Kodama, T., Nishiwaki, Y., Ogura, T., Esumi, H."Does smoking or family history influence the prognosis of patients with non-small cell lung cancer?". Oncology Reports 4, no. 6 (1997): 1221-1227. https://doi.org/10.3892/or.4.6.1221