Intrasplenic autograft of testicular tissue in rats.

  • Authors:
    • T Nishida
    • T Ueyama
    • T Sugiyama
    • A Kataoka
    • M Yakushiji
  • View Affiliations

  • Published online on: January 1, 1998     https://doi.org/10.3892/or.5.1.157
  • Pages: 157-166
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Abstract

Intrasplenic heterotransplantation of infantile testis is a conventional method to produce testicular tumors in adult castrated rodents. To avoid possible immunological interference in the tumorigenic process in allografted testis, the parenchyma of testis of Wistar strain rats aged 7 weeks was injected into the spleen of the same rat after bilateral gonadectomy. In 17 of 20 animals testicular neoplasms, resembling gonadal stromal cell tumors in human, developed from the intrasplenic gonadal tissue in the 14th month following transplantation. This autografting technique is feasible to induce testicular neoplasms in granulosa cell tumor category in high incidence, and thus deserves further attention.

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Jan-Feb 1998
Volume 5 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Nishida T, Ueyama T, Sugiyama T, Kataoka A and Yakushiji M: Intrasplenic autograft of testicular tissue in rats.. Oncol Rep 5: 157-166, 1998
APA
Nishida, T., Ueyama, T., Sugiyama, T., Kataoka, A., & Yakushiji, M. (1998). Intrasplenic autograft of testicular tissue in rats.. Oncology Reports, 5, 157-166. https://doi.org/10.3892/or.5.1.157
MLA
Nishida, T., Ueyama, T., Sugiyama, T., Kataoka, A., Yakushiji, M."Intrasplenic autograft of testicular tissue in rats.". Oncology Reports 5.1 (1998): 157-166.
Chicago
Nishida, T., Ueyama, T., Sugiyama, T., Kataoka, A., Yakushiji, M."Intrasplenic autograft of testicular tissue in rats.". Oncology Reports 5, no. 1 (1998): 157-166. https://doi.org/10.3892/or.5.1.157