Factors related to axillary lymph node metastasis in T1 breast carcinoma.

  • Authors:
    • Y Singh
    • H Nambu
    • K Yoshizawa
    • T Hatano
    • K Hioki
    • A Tsubura
  • View Affiliations

  • Published online on: March 1, 1998     https://doi.org/10.3892/or.5.2.459
  • Pages: 459-521
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The current study was performed on 38 cases of T1 breast cancers ( 2 cm in greatest diameter) to identify the factors related to recognition of axillary lymph node (AxLN) metastasis. Ten patients (26.3%) had lymph node metastases. Comparing the AxLN positive (+) group with the AxLN negative (-) group revealed that tumor size and hormone receptor status as well as age of the patients were not significantly different. However, the Ki-67 labeling index (22.2 +/- 5. 9% vs. 12.5 +/- 2.8%), the microvessel count (43.8 +/- 12.4/0.785 mm2 vs. 27.0 +/- 8.4/0.785 mm2) and bcl-2+ cases (70% vs. 29%) were significantly higher in the AxLN+ cases. These results suggest that the Ki-67 labeling index, microvessel count and Bcl-2 expression, especially when combined, are useful predictors of AxLN metastases in T1 breast cancers.

Related Articles

Journal Cover

Mar-Apr 1998
Volume 5 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Singh Y, Nambu H, Yoshizawa K, Hatano T, Hioki K and Tsubura A: Factors related to axillary lymph node metastasis in T1 breast carcinoma.. Oncol Rep 5: 459-521, 1998
APA
Singh, Y., Nambu, H., Yoshizawa, K., Hatano, T., Hioki, K., & Tsubura, A. (1998). Factors related to axillary lymph node metastasis in T1 breast carcinoma.. Oncology Reports, 5, 459-521. https://doi.org/10.3892/or.5.2.459
MLA
Singh, Y., Nambu, H., Yoshizawa, K., Hatano, T., Hioki, K., Tsubura, A."Factors related to axillary lymph node metastasis in T1 breast carcinoma.". Oncology Reports 5.2 (1998): 459-521.
Chicago
Singh, Y., Nambu, H., Yoshizawa, K., Hatano, T., Hioki, K., Tsubura, A."Factors related to axillary lymph node metastasis in T1 breast carcinoma.". Oncology Reports 5, no. 2 (1998): 459-521. https://doi.org/10.3892/or.5.2.459