Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.

  • Authors:
    • T J Chang
    • C C Juan
    • P H Yin
    • C W Chi
    • H J Tsay
  • View Affiliations

  • Published online on: March 1, 1998     https://doi.org/10.3892/or.5.2.469
  • Pages: 469-540
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Abstract

Beta-actin, cyclophilin and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) are all constantly expressed proteins that regulate cellular structures and endogenous cytoarchitectural functions. In this study, we used an in vivo N1S1 rat hepatoma model to examine changes in the expression levels of these housekeeping genes in normal and tumor liver samples. The beta-actin, cyclophilin and GAPDH genes were all up-regulated in tumor groups as compared to the controls. Our results suggest that up-regulation of beta-actin, cyclophilin and GAPDH genes may be essential for oncogenesis in hepatoma.

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Mar-Apr 1998
Volume 5 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Chang T, Juan C, Yin P, Chi C and Tsay H: Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.. Oncol Rep 5: 469-540, 1998
APA
Chang, T., Juan, C., Yin, P., Chi, C., & Tsay, H. (1998). Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.. Oncology Reports, 5, 469-540. https://doi.org/10.3892/or.5.2.469
MLA
Chang, T., Juan, C., Yin, P., Chi, C., Tsay, H."Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.". Oncology Reports 5.2 (1998): 469-540.
Chicago
Chang, T., Juan, C., Yin, P., Chi, C., Tsay, H."Up-regulation of beta-actin, cyclophilin and GAPDH in N1S1 rat hepatoma.". Oncology Reports 5, no. 2 (1998): 469-540. https://doi.org/10.3892/or.5.2.469