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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Jul-Aug 1998 Volume 5 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Jul-Aug 1998 Volume 5 Issue 4

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Article

Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.

  • Authors:
    • M Koshiji
    • E Ogura
    • H Takada
    • H Kawanishi
    • S Ikehara
    • K Hioki

  • View Affiliations / Copyright

    Affiliations: Second Department of Surgery and First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan.
  • Pages: 811-816
    |
    Published online on: July 1, 1998
       https://doi.org/10.3892/or.5.4.811
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Abstract

We compared the immunohistochemical staining patterns of carcinoembryogenic antigen (CEA), CA19-9 and proliferating cell nuclear antigen (PCNA) between specimens from 13 patients who had undergone surgery for colorectal carcinoma with lung metastasis (lung metastasis group) and specimens from 13 patients who had no evidence of recurrence or metastasis within at least 5 years after colorectal resection (no metastasis group). The PCNA labeling indices of primary and metastatic lesions were 53.29 8.88% and 63. 26 6.21% (p<0.001), respectively. The PCNA labeling index in the no metastasis group was 26 12.9% (p<0.001). There was no significant difference in the CA19-9 staining patterns between the two groups. The CEA distribution patterns in the primary and lung metastatic lesions were different even in the same case. The original tumor cells showed apical or C1 localization, whereas metastatic cells showed C2 localization. These findings indicate that patients having colorectal carcinoma with a high PCNA labeling index have a high probability of lung metastasis, and that the CEA distribution pattern would change after original tumor resection.

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Copy and paste a formatted citation
Spandidos Publications style
Koshiji M, Ogura E, Takada H, Kawanishi H, Ikehara S and Hioki K: Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.. Oncol Rep 5: 811-816, 1998.
APA
Koshiji, M., Ogura, E., Takada, H., Kawanishi, H., Ikehara, S., & Hioki, K. (1998). Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.. Oncology Reports, 5, 811-816. https://doi.org/10.3892/or.5.4.811
MLA
Koshiji, M., Ogura, E., Takada, H., Kawanishi, H., Ikehara, S., Hioki, K."Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.". Oncology Reports 5.4 (1998): 811-816.
Chicago
Koshiji, M., Ogura, E., Takada, H., Kawanishi, H., Ikehara, S., Hioki, K."Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.". Oncology Reports 5, no. 4 (1998): 811-816. https://doi.org/10.3892/or.5.4.811
Copy and paste a formatted citation
x
Spandidos Publications style
Koshiji M, Ogura E, Takada H, Kawanishi H, Ikehara S and Hioki K: Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.. Oncol Rep 5: 811-816, 1998.
APA
Koshiji, M., Ogura, E., Takada, H., Kawanishi, H., Ikehara, S., & Hioki, K. (1998). Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.. Oncology Reports, 5, 811-816. https://doi.org/10.3892/or.5.4.811
MLA
Koshiji, M., Ogura, E., Takada, H., Kawanishi, H., Ikehara, S., Hioki, K."Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.". Oncology Reports 5.4 (1998): 811-816.
Chicago
Koshiji, M., Ogura, E., Takada, H., Kawanishi, H., Ikehara, S., Hioki, K."Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.". Oncology Reports 5, no. 4 (1998): 811-816. https://doi.org/10.3892/or.5.4.811
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