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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Jul-Aug 1998 Volume 5 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Adeno-associated virus vector mediated transduction of primary normal human breast epithelial cells.

J Yang, Y Hirokawa, C Dougherty, P Colosi, J H Yang, S Nandi
Pages: 793-800
Published online on: 01 July 1998

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Article

Immortalization of human oral keratinocytes is associated with elevation of telomerase activity and shortening of telomere length.

W Guo, M K Kang, H J Kim, N H Park
Pages: 799-1603
Published online on: 01 July 1998

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Article

Immunohistochemical localization of metallothionein in hepatocellular carcinoma: preferential expression in non-cancerous cirrhotic nodules.

K Tanimoto, S M Akbar, Y Yamauchi, K Michitaka, N Horiike, M Onji
Pages: 805-814
Published online on: 01 July 1998

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Article

Clinicopathologic and immunohistochemical analyses in lung metastasis of colorectal carcinoma.

M Koshiji, E Ogura, H Takada, H Kawanishi, S Ikehara, K Hioki
Pages: 811-816
Published online on: 01 July 1998

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Article

Hepatocyte growth factor and Met/HGF receptors in patients with gastric adenocarcinoma.

C W Wu, A F Li, C W Chi, W W Chung, T Y Liu, W Y Lui, F K P'eng
Pages: 817-839
Published online on: 01 July 1998

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Article

Immunisation of colorectal cancer patients with autologous tumour cells.

A C Diederichsen, A C Stenholm, O Kronborg, C Fenger, J C Jensenius, J Zeuthen, T Kristensen, P B Christensen
Pages: 823-829
Published online on: 01 July 1998

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Article

Effect of the nitrosourea anti-tumor chemotherapeutical agent MCNU on five human myeloma cell lines.

T Otsuki, H Sakaguchi, O Yamada, Y Yawata, A Ueki
Pages: 827-859
Published online on: 01 July 1998

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Article

A case of biliary cystadenoma with obstructive jaundice.

A Taketomi, R Tamada, K Takenaka, R Kawano, T Maeda, K Sugimachi
Pages: 833-838
Published online on: 01 July 1998

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Article

Effects of azoxymethane on X-ray induced intestinal metaplasia in Donryu rats.

H Watanabe, N Fujimoto, Y Masaoka, M Kurosumi, T Oguri, T Takahashi, S Kido, S Hirata, K Kuramoto, S Shoji, O Katoh
Pages: 837-877
Published online on: 01 July 1998

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Article

Low-grade malignant tumors of the lung: is lymph node dissection necessary?

M Kamiyoshihara, T Hirai, O Kawashima, S Ishikawa, Y Morishita, A Maeshima
Pages: 841-844
Published online on: 01 July 1998

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Article

The elevated mRNA content as a potential indicator of precancerous states of the gallbladder mucosa in patients with pancreaticobiliary maljunction.

Y Miura, Y Ichikawa, T Ishikawa, H Sekido, A Nakano, M Mitsuhashi, H Shimada
Pages: 845-896
Published online on: 01 July 1998

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Case Report

Relapse of pulmonary Mycobacterium kansasii disease associated with large-cell cancer of the lung: a case report.

W Domej, A Maier, F Schmidt, H P Dimai, G H Wirnsberger
Pages: 853-859
Published online on: 01 July 1998

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Article

Anhydroretinol, a retinoid active in preventing mammary cancer induced in rats by N-methyl-N-nitrosourea.

Y F Shealy, D L Hill, B P Sani, I Eto, M M Juliana, C J Crubbs
Pages: 857-917
Published online on: 01 July 1998

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Article

A clinicopathologic study of the resected cases of adenosquamous carcinoma of the lung.

M Kamiyoshihara, T Hirai, O Kawashima, S Ishikawa, Y Morishita, A Maeshima
Pages: 861-866
Published online on: 01 July 1998

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Article

Ki-67 antigen expression in relation to clinicopathological variables and prognosis in gastric cancer.

S Kikuyama, T Kubota, K Shimizu, M Miyakita
Pages: 867-937
Published online on: 01 July 1998

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Article

Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.

H Shimada, K Nakajima, T Ochiai, Y Koide, S I Okazumi, H Matsubara, A Takeda, Y Miyazawa, M Arima, K Isono
Pages: 871-875
Published online on: 01 July 1998

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Article

Different expression patterns of MMP-2 and MMP-9 in breast cancer.

S Y Rha, W I Yang, J H Kim, J K Roh, J S Min, K S Lee, B S Kim, H C Chung
Pages: 875-884
Published online on: 01 July 1998

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Article

A pilot study of nedaplatin and etoposide for recurrent gynecological malignancies.

S Adachi, T Ogasawara, N Yamasaki, H Shibahara, Y Tsuji, T Takemura, K Koyama
Pages: 881-885
Published online on: 01 July 1998

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Article

Time elapsing from cancer diagnosis and anxiety in women attending cancer genetic clinics.

C Julian-Reynier, F Eisinger, F Chabal, Y Aurran, Y J Bignon, C Nogues, M Machelard, C Maugard, P Vennin, H Sobol
Pages: 885-893
Published online on: 01 July 1998

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Article

The effect of amiloride on the metastatic properties of prostate cancer in the Dunning rat model.

M J Pilat, J E Lehr, M M Quigley, K J Pienta
Pages: 889-981
Published online on: 01 July 1998

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Article

A phase II study of bromocriptine in patients with androgen-independent prostate cancer.

J Horti, W D Figg, B Weinberger, D Kohler, O Sartor
Pages: 893-899
Published online on: 01 July 1998

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Article

First line chemotherapy in patients with brain metastases from non-small and small cell lung cancer.

D Tummarello, P Lippe, R Bracci, D Mari, M C Monterubbianesi, N Battelli
Pages: 897-1797
Published online on: 01 July 1998

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Article

Variable levels of bcl-2, bcl-x and bax mRNA in bladder cancer progression.

P Gazzaniga, A Gradilone, I Silvestri, O Gandini, L Giuliani, A Vincenzoni, M Gallucci, L Frati, A M Agliano
Pages: 901-905
Published online on: 01 July 1998

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Article

Epidemiological aspects of cutaneous malignant melanoma (review).

D Serraino, L Fratino, W Gianni, C Campisi, M Pietropaolo, G Trimarco, V Marigliano
Pages: 905-914
Published online on: 01 July 1998

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Article

A methylenetetrahydrofolate reductase polymorphism is associated with expression of p16 in human lung cancer.

H Kamiya, K Kawakami, T Miyanaga, K Omura, M Oda, S Murakami, Y Watanabe
Pages: 911-915
Published online on: 01 July 1998

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Article

Paclitaxel in anthracycline-treated breast cancer patients.

P Pugliese, S Brugnatelli, M Giordano, M Danova, A De Monte, A Richetti, S Fava, E Rinaldi, V Fregoni, C Epifani, A Riccardi
Pages: 915-923
Published online on: 01 July 1998

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Article

The effect of hydrazine sulfate on prostate cancer growth.

J M Kamradt, K J Pienta
Pages: 919-940
Published online on: 01 July 1998

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Article

Collecting duct carcinomas of the kidney: a comparative loss of heterozygosity study with clear cell renal cell carcinoma.

F Fogt, Z Zhuang, W M Linehan, M J Merino
Pages: 923-929
Published online on: 01 July 1998

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Article

Prognostic value of low density lipoprotein receptor expression in colorectal carcinoma.

M G Caruso, A R Osella, M Notarnicola, P Berloco, S Leo, C Bonfiglio, A Di Leo
Pages: 927-957
Published online on: 01 July 1998

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Article

Single-dose etoposide in advanced pancreatic and biliary cancer, a phase II study.

K Ekstrom, K Hoffman, T Linne, B Eriksson, B Glimelius
Pages: 931-935
Published online on: 01 July 1998

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Article

Undiagnosed adult T-cell leukemia/lymphoma in central Brooklyn, NY.

S L Welles, H Dosik, E Joseph, P H Levine
Pages: 935-942
Published online on: 01 July 1998

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Article

Clinicopathologic analysis of mullerian adenosarcoma: the M.D. Anderson Cancer Center experience.

C F Verschraegen, A Vasuratna, C Edwards, R Freedman, A P Kudelka, C Tornos, J J Kavanagh
Pages: 939-983
Published online on: 01 July 1998

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Article

Early gastric cancer in the province of Forlì: follow-up of 337 patients in a high risk region for gastric cancer.

L Saragoni, M Gaudio, A Vio, S Folli, O Nanni, A Saragoni
Pages: 945-953
Published online on: 01 July 1998

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Article

Bone tumor radiograph review by pathologists prior to pathologic diagnosis: a receiver operator curve analysis of diagnostic utility.

L J Layfield, J C Lenel, J R Crim, D Renfrew, W F Coulson, B Wittels, R Hammadeh, R M Hanna, M Hitchcock, M B Cohen
Pages: 949-1002
Published online on: 01 July 1998

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Article

Basic fibroblast growth factor in serum and urine of patients with head and neck cancer.

A Leunig, S Tauber, R Spaett, G Grevers, M Leunig
Pages: 955-963
Published online on: 01 July 1998

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Article

Effects of dietary anticarcinogens on rat gastrointestinal glutathione peroxidase activity.

E M van Lieshout, M P Ekkel, M M Bedaf, W A Nijhoff, W H Peters
Pages: 959-1022
Published online on: 01 July 1998

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Article

Modifications in the carcinogen-metabolizing capacity of mouse liver treated with N-nitroso compounds.

S L Habib, A F Badawi, H A Aweny, M H Mostafa
Pages: 965-974
Published online on: 01 July 1998

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Article

Concomitant treatment with mild hyperthermia, cisplatin and low dose-rate irradiation in human ovarian cancer cells sensitive and resistant to cisplatin.

G P Raaphorst, J Maio, C E Ng, D J Stewart
Pages: 971-978
Published online on: 01 July 1998

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Article

nm23 protein expression in renal cell tumors: the role of the cell type.

A Ayhan, A Usubütün, H Ozen, W Yasui, E Tahara
Pages: 979-1062
Published online on: 01 July 1998

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Article

Vascular invasion in high grade sarcoma of the extremity is associated with short overall survival.

O Merimsky, J Isakov, Y Kollender, A Nirkin, M Inbar, I Meller
Pages: 985-994
Published online on: 01 July 1998

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Article

Evidence for selective use of bone scans in early stage breast cancer.

D Hadley, B Fowble, M H Torosian
Pages: 991-994
Published online on: 01 July 1998

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Article

Electrophoresis of BRCA1 oncosuppressor.

D Bernard-Gallon, F De Oliveira, D Favy, C Hizel, J C Maurizis, P Rio, Y J Bignon
Pages: 995-1002
Published online on: 01 July 1998

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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