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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Nov-Dec 1998 Volume 5 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Nov-Dec 1998 Volume 5 Issue 6

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Article

Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.

  • Authors:
    • M Kitamura
    • M Toi
    • K Arai
    • Y Iwasaki
    • H Suzuki
    • K Matsuo

  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Tokyo Metropolitan Komagome Hospital, Bunkyo-ku, Tokyo 113-8677, Japan.
  • Pages: 1419-1443
    |
    Published online on: November 1, 1998
       https://doi.org/10.3892/or.5.6.1419
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Abstract

VEGF (vascular endothelial growth factor) is known to play crucial roles in tumor angiogenesis. In 281 gastric cancer patients, aberrant increase of VEGF level was observed in 36 patients (12.8%). In 14 recurrent patients, 8 showed an increase of VEGF. The serum VEGF levels of stage IV cancer were significantly higher than those of stage I. The serum levels of recurrent patients were significantly higher than those of stage I, II and III. VEGF levels of patients with serosal invasion were significantly higher than those of patients without serosal invasion. In depth of invasion (t-factor), VEGF levels of t4 cancer were significantly higher than those of t1-t3. In venous infiltration of tumors, VEGF levels of v3 were significantly higher than v0 and v1. There was no significant difference with respect to H-factor and P-factor status. In eleven recurrent or advanced gastric cancer patients, serum VEGF was sequentially examined between pre- and post-chemotherapy. All of them showed a decrease of serum VEGF concentration after partial response by chemotherapy. The patients who had progressive disease after chemotherapy showed an increase of VEGF levels. Serum VEGF levels were closely related to the extent of gastric cancer and the response of chemotherapy.

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Copy and paste a formatted citation
Spandidos Publications style
Kitamura M, Toi M, Arai K, Iwasaki Y, Suzuki H and Matsuo K: Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.. Oncol Rep 5: 1419-1443, 1998.
APA
Kitamura, M., Toi, M., Arai, K., Iwasaki, Y., Suzuki, H., & Matsuo, K. (1998). Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.. Oncology Reports, 5, 1419-1443. https://doi.org/10.3892/or.5.6.1419
MLA
Kitamura, M., Toi, M., Arai, K., Iwasaki, Y., Suzuki, H., Matsuo, K."Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.". Oncology Reports 5.6 (1998): 1419-1443.
Chicago
Kitamura, M., Toi, M., Arai, K., Iwasaki, Y., Suzuki, H., Matsuo, K."Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.". Oncology Reports 5, no. 6 (1998): 1419-1443. https://doi.org/10.3892/or.5.6.1419
Copy and paste a formatted citation
x
Spandidos Publications style
Kitamura M, Toi M, Arai K, Iwasaki Y, Suzuki H and Matsuo K: Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.. Oncol Rep 5: 1419-1443, 1998.
APA
Kitamura, M., Toi, M., Arai, K., Iwasaki, Y., Suzuki, H., & Matsuo, K. (1998). Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.. Oncology Reports, 5, 1419-1443. https://doi.org/10.3892/or.5.6.1419
MLA
Kitamura, M., Toi, M., Arai, K., Iwasaki, Y., Suzuki, H., Matsuo, K."Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.". Oncology Reports 5.6 (1998): 1419-1443.
Chicago
Kitamura, M., Toi, M., Arai, K., Iwasaki, Y., Suzuki, H., Matsuo, K."Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients.". Oncology Reports 5, no. 6 (1998): 1419-1443. https://doi.org/10.3892/or.5.6.1419
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