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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
Sep-Oct 1999 Volume 6 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Sep-Oct 1999 Volume 6 Issue 5

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Article

Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?

  • Authors:
    • M Masutani
    • I Tsujino
    • T Fujie
    • M Yamaguchi
    • K Miyagi
    • T Yano
    • N Takahashi
    • Y Koya
    • T Horie

  • View Affiliations

    Affiliations: First Department of Internal Medicine, Nihon University School of Medicine, Itabashi, Tokyo 173-8610, Japan.
  • Published online on: September 1, 1999     https://doi.org/10.3892/or.6.5.1045
  • Pages: 1045-1095
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Abstract

Advanced non-small cell lung cancer (NSCLC) has proven to be remarkably resistant to standard chemotherapy regimens. One potential alternative approach is the use of dose-intensive chemotherapy with supportive therapy such as granulocyte-colony stimulating factor (G-CSF). We conducted a randomized study of dose-intensive cisplatin/vindesine/mitomycin C chemotherapy (DI-PVM) and standard cisplatin/vindesine/mitomycin C chemotherapy (PVM). A total of one hundred patients with III-IV NSCLC was randomized. The DI-PVM consisted of 3 cycles of cisplatin: 80 mg/m2 (day 1), vindesine: 3 mg/m2 (days 1 and 8) and mitomycin C: 8 mg/m2 (day 1) in 3-week intervals with concurrent G-CSF. The PVM consisted of 2 cycles of the same chemotherapy in 4-week intervals. Blood cell counts were checked twice a week, and G-CSF (2 microgram/kg, SC) was administered when the count was

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Copy and paste a formatted citation
Spandidos Publications style
Masutani M, Tsujino I, Fujie T, Yamaguchi M, Miyagi K, Yano T, Takahashi N, Koya Y and Horie T: Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?. Oncol Rep 6: 1045-1095, 1999.
APA
Masutani, M., Tsujino, I., Fujie, T., Yamaguchi, M., Miyagi, K., Yano, T. ... Horie, T. (1999). Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?. Oncology Reports, 6, 1045-1095. https://doi.org/10.3892/or.6.5.1045
MLA
Masutani, M., Tsujino, I., Fujie, T., Yamaguchi, M., Miyagi, K., Yano, T., Takahashi, N., Koya, Y., Horie, T."Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?". Oncology Reports 6.5 (1999): 1045-1095.
Chicago
Masutani, M., Tsujino, I., Fujie, T., Yamaguchi, M., Miyagi, K., Yano, T., Takahashi, N., Koya, Y., Horie, T."Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?". Oncology Reports 6, no. 5 (1999): 1045-1095. https://doi.org/10.3892/or.6.5.1045
Copy and paste a formatted citation
x
Spandidos Publications style
Masutani M, Tsujino I, Fujie T, Yamaguchi M, Miyagi K, Yano T, Takahashi N, Koya Y and Horie T: Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?. Oncol Rep 6: 1045-1095, 1999.
APA
Masutani, M., Tsujino, I., Fujie, T., Yamaguchi, M., Miyagi, K., Yano, T. ... Horie, T. (1999). Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?. Oncology Reports, 6, 1045-1095. https://doi.org/10.3892/or.6.5.1045
MLA
Masutani, M., Tsujino, I., Fujie, T., Yamaguchi, M., Miyagi, K., Yano, T., Takahashi, N., Koya, Y., Horie, T."Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?". Oncology Reports 6.5 (1999): 1045-1095.
Chicago
Masutani, M., Tsujino, I., Fujie, T., Yamaguchi, M., Miyagi, K., Yano, T., Takahashi, N., Koya, Y., Horie, T."Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?". Oncology Reports 6, no. 5 (1999): 1045-1095. https://doi.org/10.3892/or.6.5.1045
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