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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Sep-Oct 1999 Volume 6 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Chemo-radiotherapy: radiosensitizing nucleoside analogues (review).

V Gregoire, W N Hittelman, J F Rosier, L Milas
Pages: 949-1006
Published online on: 01 September 1999

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Article

Angiogenesis does not correlate with prognosis or expression of vascular endothelial growth factor in synovial sarcomas.

S Kawauchi, T Fukuda, M Tsuneyoshi
Pages: 959-1023
Published online on: 01 September 1999

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Article

Expression of cyclooxygenase-2 in human adenocarcinomas of the gastric cardia and corpus.

D Ratnasinghe, J A Tangrea, M J Roth, S M Dawsey, M Anver, B A Kasprzak, N Hu, Q H Wang, P R Taylor
Pages: 965-973
Published online on: 01 September 1999

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Article

The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.

M Mukai, S Sadahiro, N Tokunaga, K Ishizu, I Ito, T Kameya, K Ishikawa, H Iwase, T Suzuki, H Ishida, T Tajima, H Makuuchi
Pages: 969-1042
Published online on: 01 September 1999

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Article

The heterogeneous expression of MAGE-3 protein: difference between primary lesions and metastatic lymph nodes in gastric carcinoma.

N Sadanaga, H Nagashima, K Tahara, Y Yoshikawa, M Mori
Pages: 975-982
Published online on: 01 September 1999

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Article

Chemoimmunosensitization of the T24 human bladder cancer line to Fas-mediated cytotoxicity and apoptosis by cisplatin and 5-fluorouracil.

Y Mizutani, X X Wu, O Yoshida, T Shirasaka, B Bonavida
Pages: 979-1061
Published online on: 01 September 1999

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Article

Expression of p27Kip1, cyclin E and E2F-1 in primary and metastatic tumors of gastric carcinoma.

W Yasui, K Naka, T Suzuki, J Fujimoto, K Hayashi, N Matsutani, H Yokozaki, E Tahara
Pages: 983-990
Published online on: 01 September 1999

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Article

Influence of concomitant miso or NaCl treatment on induction of gastric tumors by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

H Watanabe, T Uesaka, S Kido, Y Ishimura, K Shiraki, K Kuramoto, S Hirata, S Shoji, O Katoh, N Fujimoto
Pages: 989-1082
Published online on: 01 September 1999

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Article

Thymidine phosphorylase activity and angiogenesis in gastric cancer.

Y Kakeji, Y Maehara, M Tomoda, A Kabashima, S Oda, T Ooshiro, H Baba, S Kohnoe, K Sugimachi
Pages: 995-1004
Published online on: 01 September 1999

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Article

Breast cancer in the contralateral breast: incidence and histopathology after unilateral radical treatment of the first breast cancer.

N K Raabe, T Sauer, A Erichsen, J M Nesland, S D Fossaa
Pages: 1001-1008
Published online on: 01 September 1999

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Article

Rapid death following papillary serous carcinoma of the endometrium without myometrial invasion.

M Suzuki, M Ohwada, N Kanai, I Sato
Pages: 1009-1021
Published online on: 01 September 1999

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Article

DNA ploidy as a significant prognostic factor after radical resection for large bowel carcinoma: a prospective study.

G Galizia, F Ferraraccio, E Lieto, P Castellano, M Accardo, L Pelosio, V Imperatore
Pages: 1013-1034
Published online on: 01 September 1999

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Article

Correlation between microvessel density and tumor cell proliferation with clinical factors in breast carcinomas.

G Nakamura, S Arita, K Tanaka, K Hioki, A Tsubura, N Shikata
Pages: 1023-1030
Published online on: 01 September 1999

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Article

H-ras gene amplification or mutation is not common in human primary breast cancer.

T Schondorf, A Andrack, D Niederacher, A Scharl, M Becker, H Engel, U J Gohring
Pages: 1029-1062
Published online on: 01 September 1999

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Article

Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma.

N Umesaki, T Tanaka, N Kawamura, M Miyama, T Ichimura, S Ogita
Pages: 1035-1042
Published online on: 01 September 1999

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Article

Clinical outcome in localized renal cell carcinomas related to immunoexpression of proliferating cell nuclear antigen, Ki-67 antigen, and tumor size.

H Onda, M Yasuda, A Serizawa, R Y Osamura, N Kawamura
Pages: 1039-1082
Published online on: 01 September 1999

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Article

Moderate dose-intensive chemotherapy for patients with non-small cell lung cancer: randomized trial, can it improve survival of patients with good performance status?

M Masutani, I Tsujino, T Fujie, M Yamaguchi, K Miyagi, T Yano, N Takahashi, Y Koya, T Horie
Pages: 1045-1095
Published online on: 01 September 1999

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Article

Clinical significance of hepatocyte growth factor and c-Met expression in extrahepatic biliary tract cancers.

Y Hida, T Morita, M Fujita, Y Miyasaka, S Horita, Y Fujioka, K Nagashima, H Katoh
Pages: 1051-1057
Published online on: 01 September 1999

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Article

Activation of autologous or HLA-identical sibling cytotoxic T lymphocytes by blood derived dendritic cells pulsed with tumor cell extracts.

Y Osman, M Takahashi, Z Zheng, K Toba, A Liu, T Furukawa, Y Aizawa, A Shibata, T Koike
Pages: 1057-1120
Published online on: 01 September 1999

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Article

Expression of E-cadherin/catenin complex in nasopharyngeal carcinoma: correlation with clinicopathological parameters.

P Lou, W Chen, T Sheen, J Ko, M Hsu, J Wu
Pages: 1065-1136
Published online on: 01 September 1999

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Article

Inhibition of metastases by a serum factor associated to concomitant resistance induced by unrelated murine tumors.

P Di Gianni, M Franco, R P Meiss, S Vanzulli, I Piazzon, C D Pasqualini, O D Bustuoabad, R A Ruggiero
Pages: 1073-1157
Published online on: 01 September 1999

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Case Report

Long-term control of multiple lung metastases from osteosarcoma obtained by conventional radiotherapy: a case report.

Y Shibamoto, N Horii, M Takahashi
Pages: 1085-1092
Published online on: 01 September 1999

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Article

Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring.

L Hilakivi-Clarke, E Cho, I Onojafe, M Raygada, R Clarke
Pages: 1089-1184
Published online on: 01 September 1999

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Article

Phase II trial of doxil for patients with metastatic melanoma refractory to frontline therapy.

J A Ellerhorst, A Bedikian, S Ring, A C Buzaid, O Eton, S S Legha
Pages: 1097-1106
Published online on: 01 September 1999

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Article

del(6)(q12q15) as the sole cytogenetic anomaly in a case of solitary infantile myofibromatosis.

G Stenman, N Nadal, S Persson, B Gunterberg, L Angervall
Pages: 1101-1105
Published online on: 01 September 1999

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Article

Synergistic growth inhibition and induction of apoptosis by a novel mixed backbone antisense oligonucleotide targeting CRIPTO in combination with C225 anti-EGFR monoclonal antibody and 8-Cl-cAMP in human GEO colon cancer cells.

N Normanno, G Tortora, A De Luca, G Pomatico, A Casamassimi, S Agrawal, J Mendelsohn, A R Bianco, F Ciardiello
Pages: 1105-1114
Published online on: 01 September 1999

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Case Report

Primary non-Hodgkin's lymphoma of the head of the pancreas: a case report and review of literature.

P Pecorari, N Gorji, M Melato
Pages: 1111-1116
Published online on: 01 September 1999

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Article

Ki-67 and c-jun expression in pancreatic cancer: a prognostic marker?

C Ferrara, G Tessari, A Poletti, C Giacon, T Meggiato, D Martines, G Del Favero, R Naccarato
Pages: 1117-1139
Published online on: 01 September 1999

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Article

d-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc.

R K Giri, T Parija, B R Das
Pages: 1123-1130
Published online on: 01 September 1999

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Article

Evaluation of soluble CD44 in patients with breast and colorectal carcinomas and non-Hodgkin's lymphoma.

M S Lockhart, C Waldner, C Mongini, M J Gravisaco, S Casanova, E Alvarez, S Hajos
Pages: 1129-1162
Published online on: 01 September 1999

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Article

A new method for expressing survival and life expectancy in lifetime cost-effectiveness studies that evaluate cancer patients (review).

A Messori, S Trippoli
Pages: 1135-1176
Published online on: 01 September 1999

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Article

Expression analysis of multidrug resistance associated genes in neuroblastomas.

P Bader, F Schilling, M Schlaud, R Girgert, R Handgretinger, T Klingebiel, J Treuner, C Liu, D Niethammer, J F Beck
Pages: 1143-1149
Published online on: 01 September 1999

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Article

Assessing chromosome 22 microdeletions in meningioma with new polymorphic DNA markers.

F Subke, C Pusch, K Schroder, E Meese, N Blin
Pages: 1147-1156
Published online on: 01 September 1999

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Article

Massive extramedullary disease progression in a patient with stable multiple myeloma during G-CSF priming for peripheral blood progenitor mobilization.

G Kobbe, U Germing, D Soehngen, C Aul, A Heyll
Pages: 1151-1153
Published online on: 01 September 1999

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Article

Evaluation of histochemical anthracyclin binding as potential prognostic parameter in small cell lung cancer.

K Kayser, G Kayser, S Andre, M Altiner, H Gabius
Pages: 1153-1160
Published online on: 01 September 1999

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Article

Immunohistochemical expression of p53 protein in invasive breast carcinoma: clinicopathologic correlations.

P Tan, G Ho, C Ji, E Ng, F Gao, B Bay
Pages: 1159-1222
Published online on: 01 September 1999

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Article Open Access

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Article Open Access

Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Review Open Access

Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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