The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.

  • Authors:
    • K A Hartmann
    • U M Carl
    • P Sminia
    • G Lammering
    • K A Becker
    • G Schmitt
  • View Affiliations

  • Published online on: January 1, 2000     https://doi.org/10.3892/or.7.1.131
  • Pages: 131-134
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Abstract

We investigated the ischemia-reperfusion-induced tumour growth delay as a function of ischemic time, tumour temperature, and the amount of inspired oxygen during reperfusion. The rhabdomyosarcoma R1H growing on the right flank of male WAG/Rij rats was clamped for 2 or 4 h at 20 degrees C or 37 degrees C. Five minutes prior to and 10 min during reperfusion the animals respired air, pure oxygen or carbogen (95% O2, 5% CO2). Comparison of single treatment modalities with untreated controls revealed significant tumour growth delays after clamping times of 4 h at 37 degrees C for air and pure oxygen, but not for carbogen.

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Jan-Feb 2000
Volume 7 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Hartmann K, Carl U, Sminia P, Lammering G, Becker K and Schmitt G: The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.. Oncol Rep 7: 131-134, 2000
APA
Hartmann, K., Carl, U., Sminia, P., Lammering, G., Becker, K., & Schmitt, G. (2000). The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.. Oncology Reports, 7, 131-134. https://doi.org/10.3892/or.7.1.131
MLA
Hartmann, K., Carl, U., Sminia, P., Lammering, G., Becker, K., Schmitt, G."The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.". Oncology Reports 7.1 (2000): 131-134.
Chicago
Hartmann, K., Carl, U., Sminia, P., Lammering, G., Becker, K., Schmitt, G."The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.". Oncology Reports 7, no. 1 (2000): 131-134. https://doi.org/10.3892/or.7.1.131