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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Jan-Feb 2000 Volume 7 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells.

S Balabhadrapathruni, T J Thomas, E J Yurkow, P S Amenta, T Thomas
Pages: 3-15
Published online on: 01 January 2000

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Article

Expression of the alpha6beta4 integrin provides prognostic information in bladder cancer.

H B Grossman, C Lee, J Bromberg, M Liebert
Pages: 13-19
Published online on: 01 January 2000

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Article

Estrogen and progesterone receptors can be maintained in normal human breast epithelial cells in primary culture and after transplantation into nude mice.

J Yang, A Liu, C Dougherty, X Chen, R Guzman, S Nandi
Pages: 17-38
Published online on: 01 January 2000

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Article

In vivo efficacy and pharmacokinetics of a new hypoxic cell radiosensitizer doranidazole in SUIT-2 human pancreatic cancer xenografted in mouse pancreas.

H Matsuoka, Y Shibamoto, T Kubota, M Tsujitani, T Majima
Pages: 23-29
Published online on: 01 January 2000

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Article

Expression of cathepsin B and cystatin C in the human adenohypophysis and in pituitary adenomas.

K Yoshimura, T Tsuchida, K Kawamoto
Pages: 27-58
Published online on: 01 January 2000

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Article

A human B-cell CLL model established by transplantation of JOK-1 cells into SCID mice and an anti-leukemia efficacy of fludarabine phosphate.

L Bai, K Kon, M Tatsumi, H Ito, S Hayashi, M Brautigam
Pages: 33-41
Published online on: 01 January 2000

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Article

Microsatellite instability and MLH1 and MSH2 germline defects are related to clinicopathological features in sporadic colorectal cancer.

M Fornasarig, A Viel, M Valentini, E Capozzi, R Sigon, A De Paoli, L Della Puppa, M Boiocchi
Pages: 39-82
Published online on: 01 January 2000

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Article

Evidence for Fas counter attack in vivo from a study of colorectal cancer.

E Arbuckle, N E Langlois, O Eremin, S D Heys
Pages: 45-52
Published online on: 01 January 2000

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Article

Selective beta2-adrenoceptor agonist enhances sensitivity to cisplatin in non-small cell lung cancer cell line.

T Bando, M Fujimura, K Kasahara, T Ueno, T Matsuda
Pages: 49-101
Published online on: 01 January 2000

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Article

Early diagnosis and evaluation of therapy in postoperative recurrent cervical cancers by positron emission tomography.

N Umesaki, T Tanaka, M Miyama, O Tokuyama, N Kawamura, S Ogita, J Kawabe, T Okamura, K Koyama, H Ochi
Pages: 53-59
Published online on: 01 January 2000

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Article

Endoscopic prediction of tumor depth of gastric carcinoma for assessing the indication of its limited resection.

T Namieno, K Koito, T Hiigashi, M Takahashi, T Shimamura, K Yamashita, Y Kondo
Pages: 57-118
Published online on: 01 January 2000

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Article

Signal transduction in adherent and non-adherent human cell lines after fibronectin stimulation.

M Malecki, H Trembacz, P Sroczynska, P Janik
Pages: 63-70
Published online on: 01 January 2000

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Article

The role of interleukin-6 in inhibition of lung metastasis in subcutaneous tumor-bearing mice.

K Inoue, S Okabe, E Sueoka, N Sueoka, T Tabei, M Suganuma
Pages: 69-142
Published online on: 01 January 2000

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Article

Bladder carcinoma evaluated by transvaginal ultrasonography.

H Tanaka, S Nakano, A Ishihara, N Toyoda
Pages: 75-82
Published online on: 01 January 2000

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Article

Cytotoxicity of docosahexaenoic acid and eicosapentaenoic acid in tumor cells and the dependence on binding to serum proteins and incorporation into intracellular lipids.

K Kageyama, R Yamada, S Otani, Y Onoyama, I Yano, W Yamaguchi, Y Yamaguchi, H Kogawa, N Nagao, N Miwa
Pages: 79-162
Published online on: 01 January 2000

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Article

Preoperative evaluation by whole-body 18F-fluorodeoxyglucose positron emission tomography in patients with primary colorectal cancer.

M Mukai, S Sadahiro, S Yasuda, H Ishida, N Tokunaga, T Tajima, H Makuuchi
Pages: 85-92
Published online on: 01 January 2000

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Article

A case-control study of uterine endometrial cancer of pre- and post-menopausal women.

K Niwa, A Imai, M Hashimoto, Y Yokoyama, H Mori, Y Matsuda, T Tamaya
Pages: 89-182
Published online on: 01 January 2000

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Article

Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.

M Volm, R Koomagi
Pages: 95-103
Published online on: 01 January 2000

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Article

Aberration of p53 and DCC in gastric and colorectal cancer.

M Kataoka, T Okabayashi, H Johira, S Nakatani, A Nakashima, A Takeda, M Nishizaki, K Orita, N Tanaka
Pages: 99-202
Published online on: 01 January 2000

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Article

Breast cancer shortly after the diagnosis of interstitial pneumonia associated with polymyositis.

H Satoh, M Ohtsuka, Y T Yamashita, H Kamma, T Yashiro, K Sekizawa
Pages: 105-111
Published online on: 01 January 2000

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Article

Utility of liposomes coated with polysaccharide bearing 1-amino-lactose as targeting chemotherapy for AH66 hepatoma cells.

M Yamamoto, K Ichinose, N Ishii, T Khoji, K Akiyoshi, N Moriguchi, J Sunamoto, T Kanematsu
Pages: 107-118
Published online on: 01 January 2000

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Article

Genetic heterogeneity and progression in different areas within high-grade diffuse astrocytoma.

S Shuangshoti, Y Navalitloha, V Kasantikul, A Mutirangura
Pages: 113-120
Published online on: 01 January 2000

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Article

Enhancement of gene transfer efficiency into human cancer cells by modification of retroviral vectors and addition of chemicals.

J J Song, J H Kim, H Lee, E Kim, J Kim, Y S Park, J Ahn, N C Yoo, J K Roh, B S Kim
Pages: 119-143
Published online on: 01 January 2000

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Article

Alternative gonadotropin-releasing hormone processing products secreted from endometrial carcinoma.

A Takagi, A Imai, T Tamaya
Pages: 125-134
Published online on: 01 January 2000

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Article

The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.

K A Hartmann, U M Carl, P Sminia, G Lammering, K A Becker, G Schmitt
Pages: 131-134
Published online on: 01 January 2000

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Article

Regulation of estrogen receptor and epidermal growth factor receptor by tamoxifen under high and low estrogen environments in MCF-7 cells grown in athymic mice.

Y Koibuchi, Y Iino, T Uchida, T Andoh, Y Horii, M Nagasawa, J Horiguchi, M Maemura, H Takei, T Yokoe, Y Morishita
Pages: 135-175
Published online on: 01 January 2000

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Article

Balloon-occluded arterial infusion chemotherapy, simple total hysterectomy, and radiotherapy as a useful combination-therapy for advanced cancer of the uterine cervix.

O Ishiko, T Sumi, T Yasui, Y Matsumoto, N Kawamura, S Ogita, T Kamino, K Nakamura, R Yamada
Pages: 141-145
Published online on: 01 January 2000

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Case Report

Interferon alpha-2b at low doses as long-term antiangiogenic treatment of a metastatic intracranial hemangioendothelioma: a case report.

G Palmieri, L Montella, A Martignetti, A R Bianco
Pages: 145-154
Published online on: 01 January 2000

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Article

NK cells mediate the anti-tumor effects of E1-deleted, type 5 adenovirus in a human tumor xenograft model.

L L Nielsen
Pages: 151-156
Published online on: 01 January 2000

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Article

Expression and regulation of estrogen receptor beta in human breast tumors and cell lines.

E A Vladusic, A E Hornby, F K Guerra-Vladusic, J Lakins, R Lupu
Pages: 157-224
Published online on: 01 January 2000

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Article

Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.

J E Nelson, R E Harris
Pages: 169-239
Published online on: 01 January 2000

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Article

Pharmacokinetics of intrapleural cisplatin for the treatment of malignant pleural effusions.

S Monjanel-Mouterde, C Frenay, J Catalin, C Boutin, A Durand, P Astoul
Pages: 171-176
Published online on: 01 January 2000

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Article

Potentiatied anti-tumor effectiveness of combined therapy with interleukin-12 and mitoxantrone of L1210 leukemia in vivo.

J Golab, R Zagozdzon, K Kozar, R Kaminski, A Giermasz, T Stoklosa, W Lasek, M Jakobisiak
Pages: 177-258
Published online on: 01 January 2000

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Article

Lack of effect by prostaglandin F2alpha on the proliferation of the HCT-8 and HT-29 human adenocarcinoma cell lines.

G Cassano, G Gasparre, F Susca, C Lippe, G Guanti
Pages: 183-189
Published online on: 01 January 2000

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Article

Local and systemic treatment in small cell carcinoma of the esophagus.

A Maier, M Woltsche, B Fell, U Prettenhofer, W Domej, G M Roger, H Pinter, F M Smolle-Juttner
Pages: 187-279
Published online on: 01 January 2000

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Article

Clofazimine and B4121 sensitize an intrinsically resistant human colon cancer cell line to P-glycoprotein substrates.

C E van Rensburg, G K Joone, J F O'Sullivan
Pages: 193-198
Published online on: 01 January 2000

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Article

Concordance between tumour cell activation by epidermal growth factor and alteration of cell sensitivity to cisplatin and lymphokine-activated killer cell activity.

A M Nouri, S T Zubairi, M V Russell, T Moss, H Cannell, A M Paris, M Symes, R T Oliver
Pages: 197-398
Published online on: 01 January 2000

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Article

Carcinomatous meningitis and solid tumours.

C Strady, A Ricciarelli, S Nasca, F Liautaud-Roger, P Coninx
Pages: 203-210
Published online on: 01 January 2000

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Article Open Access

Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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Retraction Open Access

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício De Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑De‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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