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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Jan-Feb 2000 Volume 7 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells.

S Balabhadrapathruni, T J Thomas, E J Yurkow, P S Amenta, T Thomas
Pages: 3-15
Published online on: 01 January 2000

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Article

Expression of the alpha6beta4 integrin provides prognostic information in bladder cancer.

H B Grossman, C Lee, J Bromberg, M Liebert
Pages: 13-19
Published online on: 01 January 2000

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Article

Estrogen and progesterone receptors can be maintained in normal human breast epithelial cells in primary culture and after transplantation into nude mice.

J Yang, A Liu, C Dougherty, X Chen, R Guzman, S Nandi
Pages: 17-38
Published online on: 01 January 2000

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Article

In vivo efficacy and pharmacokinetics of a new hypoxic cell radiosensitizer doranidazole in SUIT-2 human pancreatic cancer xenografted in mouse pancreas.

H Matsuoka, Y Shibamoto, T Kubota, M Tsujitani, T Majima
Pages: 23-29
Published online on: 01 January 2000

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Article

Expression of cathepsin B and cystatin C in the human adenohypophysis and in pituitary adenomas.

K Yoshimura, T Tsuchida, K Kawamoto
Pages: 27-58
Published online on: 01 January 2000

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Article

A human B-cell CLL model established by transplantation of JOK-1 cells into SCID mice and an anti-leukemia efficacy of fludarabine phosphate.

L Bai, K Kon, M Tatsumi, H Ito, S Hayashi, M Brautigam
Pages: 33-41
Published online on: 01 January 2000

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Article

Microsatellite instability and MLH1 and MSH2 germline defects are related to clinicopathological features in sporadic colorectal cancer.

M Fornasarig, A Viel, M Valentini, E Capozzi, R Sigon, A De Paoli, L Della Puppa, M Boiocchi
Pages: 39-82
Published online on: 01 January 2000

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Article

Evidence for Fas counter attack in vivo from a study of colorectal cancer.

E Arbuckle, N E Langlois, O Eremin, S D Heys
Pages: 45-52
Published online on: 01 January 2000

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Article

Selective beta2-adrenoceptor agonist enhances sensitivity to cisplatin in non-small cell lung cancer cell line.

T Bando, M Fujimura, K Kasahara, T Ueno, T Matsuda
Pages: 49-101
Published online on: 01 January 2000

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Article

Early diagnosis and evaluation of therapy in postoperative recurrent cervical cancers by positron emission tomography.

N Umesaki, T Tanaka, M Miyama, O Tokuyama, N Kawamura, S Ogita, J Kawabe, T Okamura, K Koyama, H Ochi
Pages: 53-59
Published online on: 01 January 2000

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Article

Endoscopic prediction of tumor depth of gastric carcinoma for assessing the indication of its limited resection.

T Namieno, K Koito, T Hiigashi, M Takahashi, T Shimamura, K Yamashita, Y Kondo
Pages: 57-118
Published online on: 01 January 2000

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Article

Signal transduction in adherent and non-adherent human cell lines after fibronectin stimulation.

M Malecki, H Trembacz, P Sroczynska, P Janik
Pages: 63-70
Published online on: 01 January 2000

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Article

The role of interleukin-6 in inhibition of lung metastasis in subcutaneous tumor-bearing mice.

K Inoue, S Okabe, E Sueoka, N Sueoka, T Tabei, M Suganuma
Pages: 69-142
Published online on: 01 January 2000

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Article

Bladder carcinoma evaluated by transvaginal ultrasonography.

H Tanaka, S Nakano, A Ishihara, N Toyoda
Pages: 75-82
Published online on: 01 January 2000

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Article

Cytotoxicity of docosahexaenoic acid and eicosapentaenoic acid in tumor cells and the dependence on binding to serum proteins and incorporation into intracellular lipids.

K Kageyama, R Yamada, S Otani, Y Onoyama, I Yano, W Yamaguchi, Y Yamaguchi, H Kogawa, N Nagao, N Miwa
Pages: 79-162
Published online on: 01 January 2000

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Article

Preoperative evaluation by whole-body 18F-fluorodeoxyglucose positron emission tomography in patients with primary colorectal cancer.

M Mukai, S Sadahiro, S Yasuda, H Ishida, N Tokunaga, T Tajima, H Makuuchi
Pages: 85-92
Published online on: 01 January 2000

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Article

A case-control study of uterine endometrial cancer of pre- and post-menopausal women.

K Niwa, A Imai, M Hashimoto, Y Yokoyama, H Mori, Y Matsuda, T Tamaya
Pages: 89-182
Published online on: 01 January 2000

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Article

Prognostic relevance of c-Myc and caspase-3 for patients with non-small cell lung cancer.

M Volm, R Koomagi
Pages: 95-103
Published online on: 01 January 2000

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Article

Aberration of p53 and DCC in gastric and colorectal cancer.

M Kataoka, T Okabayashi, H Johira, S Nakatani, A Nakashima, A Takeda, M Nishizaki, K Orita, N Tanaka
Pages: 99-202
Published online on: 01 January 2000

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Article

Breast cancer shortly after the diagnosis of interstitial pneumonia associated with polymyositis.

H Satoh, M Ohtsuka, Y T Yamashita, H Kamma, T Yashiro, K Sekizawa
Pages: 105-111
Published online on: 01 January 2000

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Article

Utility of liposomes coated with polysaccharide bearing 1-amino-lactose as targeting chemotherapy for AH66 hepatoma cells.

M Yamamoto, K Ichinose, N Ishii, T Khoji, K Akiyoshi, N Moriguchi, J Sunamoto, T Kanematsu
Pages: 107-118
Published online on: 01 January 2000

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Article

Genetic heterogeneity and progression in different areas within high-grade diffuse astrocytoma.

S Shuangshoti, Y Navalitloha, V Kasantikul, A Mutirangura
Pages: 113-120
Published online on: 01 January 2000

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Article

Enhancement of gene transfer efficiency into human cancer cells by modification of retroviral vectors and addition of chemicals.

J J Song, J H Kim, H Lee, E Kim, J Kim, Y S Park, J Ahn, N C Yoo, J K Roh, B S Kim
Pages: 119-143
Published online on: 01 January 2000

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Article

Alternative gonadotropin-releasing hormone processing products secreted from endometrial carcinoma.

A Takagi, A Imai, T Tamaya
Pages: 125-134
Published online on: 01 January 2000

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Article

The influence of inspiratory hyperoxia on ischemia-reperfusion-induced tumour growth delay.

K A Hartmann, U M Carl, P Sminia, G Lammering, K A Becker, G Schmitt
Pages: 131-134
Published online on: 01 January 2000

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Article

Regulation of estrogen receptor and epidermal growth factor receptor by tamoxifen under high and low estrogen environments in MCF-7 cells grown in athymic mice.

Y Koibuchi, Y Iino, T Uchida, T Andoh, Y Horii, M Nagasawa, J Horiguchi, M Maemura, H Takei, T Yokoe, Y Morishita
Pages: 135-175
Published online on: 01 January 2000

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Article

Balloon-occluded arterial infusion chemotherapy, simple total hysterectomy, and radiotherapy as a useful combination-therapy for advanced cancer of the uterine cervix.

O Ishiko, T Sumi, T Yasui, Y Matsumoto, N Kawamura, S Ogita, T Kamino, K Nakamura, R Yamada
Pages: 141-145
Published online on: 01 January 2000

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Case Report

Interferon alpha-2b at low doses as long-term antiangiogenic treatment of a metastatic intracranial hemangioendothelioma: a case report.

G Palmieri, L Montella, A Martignetti, A R Bianco
Pages: 145-154
Published online on: 01 January 2000

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Article

NK cells mediate the anti-tumor effects of E1-deleted, type 5 adenovirus in a human tumor xenograft model.

L L Nielsen
Pages: 151-156
Published online on: 01 January 2000

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Article

Expression and regulation of estrogen receptor beta in human breast tumors and cell lines.

E A Vladusic, A E Hornby, F K Guerra-Vladusic, J Lakins, R Lupu
Pages: 157-224
Published online on: 01 January 2000

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Article

Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.

J E Nelson, R E Harris
Pages: 169-239
Published online on: 01 January 2000

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Article

Pharmacokinetics of intrapleural cisplatin for the treatment of malignant pleural effusions.

S Monjanel-Mouterde, C Frenay, J Catalin, C Boutin, A Durand, P Astoul
Pages: 171-176
Published online on: 01 January 2000

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Article

Potentiatied anti-tumor effectiveness of combined therapy with interleukin-12 and mitoxantrone of L1210 leukemia in vivo.

J Golab, R Zagozdzon, K Kozar, R Kaminski, A Giermasz, T Stoklosa, W Lasek, M Jakobisiak
Pages: 177-258
Published online on: 01 January 2000

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Article

Lack of effect by prostaglandin F2alpha on the proliferation of the HCT-8 and HT-29 human adenocarcinoma cell lines.

G Cassano, G Gasparre, F Susca, C Lippe, G Guanti
Pages: 183-189
Published online on: 01 January 2000

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Article

Local and systemic treatment in small cell carcinoma of the esophagus.

A Maier, M Woltsche, B Fell, U Prettenhofer, W Domej, G M Roger, H Pinter, F M Smolle-Juttner
Pages: 187-279
Published online on: 01 January 2000

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Article

Clofazimine and B4121 sensitize an intrinsically resistant human colon cancer cell line to P-glycoprotein substrates.

C E van Rensburg, G K Joone, J F O'Sullivan
Pages: 193-198
Published online on: 01 January 2000

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Article

Concordance between tumour cell activation by epidermal growth factor and alteration of cell sensitivity to cisplatin and lymphokine-activated killer cell activity.

A M Nouri, S T Zubairi, M V Russell, T Moss, H Cannell, A M Paris, M Symes, R T Oliver
Pages: 197-398
Published online on: 01 January 2000

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Article

Carcinomatous meningitis and solid tumours.

C Strady, A Ricciarelli, S Nasca, F Liautaud-Roger, P Coninx
Pages: 203-210
Published online on: 01 January 2000

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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