search button

Expression of variant CD44 containing variant exon v8-10 in gallbladder cancer.

  • Authors:
    • A Yamaguchi
    • M Zhang
    • T Goi
    • T Fujita
    • S Niimoto
    • K Katayama
    • K Hirose

  • View Affiliations

  • Published online on: May 1, 2000     https://doi.org/10.3892/or.7.3.541
  • Pages: 541-545
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

We studied the Cd44v8-10 expression in gallbladder cancer immunohistochemically. Eighteen of 37 gallbladder cancer tissues expressed CD44v8-10. There were significant correlations between CD44v8-10 immunoreactivity and perineural invasion, venous invasion, and lymph node metastasis. Patients with CD44v8-10-positive tumors showed poor prognoses, whereas those with CD44v8-10-negative tumors had favorable prognoses. A multivariate analysis using the Cox regression model showed the immunoreactivity of CD44v8-10 to be an independent prognostic indicator of gallbladder cancer. The results suggest that CD44v8-10 expression may be a biologic marker of prognostic significance in gallbladder cancer.

Related Articles

Journal Cover

May-Jun 2000
Volume 7 Issue 3

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 4.2
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 8.4
  • CiteScore Rank: Q1: #68/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.786
  • SCImago Journal Rank (SJR): 0.812
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
Yamaguchi A, Zhang M, Goi T, Fujita T, Niimoto S, Katayama K and Hirose K: Expression of variant CD44 containing variant exon v8-10 in gallbladder cancer.. Oncol Rep 7: 541-545, 2000
APA
Yamaguchi, A., Zhang, M., Goi, T., Fujita, T., Niimoto, S., Katayama, K., & Hirose, K. (2000). Expression of variant CD44 containing variant exon v8-10 in gallbladder cancer.. Oncology Reports, 7, 541-545. https://doi.org/10.3892/or.7.3.541
MLA
Yamaguchi, A., Zhang, M., Goi, T., Fujita, T., Niimoto, S., Katayama, K., Hirose, K."Expression of variant CD44 containing variant exon v8-10 in gallbladder cancer.". Oncology Reports 7.3 (2000): 541-545.
Chicago
Yamaguchi, A., Zhang, M., Goi, T., Fujita, T., Niimoto, S., Katayama, K., Hirose, K."Expression of variant CD44 containing variant exon v8-10 in gallbladder cancer.". Oncology Reports 7, no. 3 (2000): 541-545. https://doi.org/10.3892/or.7.3.541