Test for fused-cell origin of tumors with Mus caroli carrying glucose-6-phosphate dehydrogenase cellular mosaicism.

  • Authors:
    • K Tanaka
    • A Ootsuyama
    • H Tanooka
    • J D Ansell
  • View Affiliations

  • Published online on: July 1, 2000     https://doi.org/10.3892/or.7.4.897
  • Pages: 897-905
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Abstract

A test system for examining the fused cell-origin of tumors was developed by application of Mus caroli carrying the X-chromosome inactivation cellular mosaicism for G6PD. A G6PD heterodimer pattern is expected if a tumor is initiated from a fused cell. Among tumors induced by subcutaneous injection of a high dose of MCA, three tumors exhibited a single G6PD phenotype and one tumor exhibited a multiple G6PD phenotype; however, the G6PD heterodimer pattern was not found. Although the results obtained were not conclusive, this system is thought to be useful for detecting a possible fused cell-origin of tumors.

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Jul-Aug 2000
Volume 7 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Tanaka K, Ootsuyama A, Tanooka H and Ansell J: Test for fused-cell origin of tumors with Mus caroli carrying glucose-6-phosphate dehydrogenase cellular mosaicism.. Oncol Rep 7: 897-905, 2000
APA
Tanaka, K., Ootsuyama, A., Tanooka, H., & Ansell, J. (2000). Test for fused-cell origin of tumors with Mus caroli carrying glucose-6-phosphate dehydrogenase cellular mosaicism.. Oncology Reports, 7, 897-905. https://doi.org/10.3892/or.7.4.897
MLA
Tanaka, K., Ootsuyama, A., Tanooka, H., Ansell, J."Test for fused-cell origin of tumors with Mus caroli carrying glucose-6-phosphate dehydrogenase cellular mosaicism.". Oncology Reports 7.4 (2000): 897-905.
Chicago
Tanaka, K., Ootsuyama, A., Tanooka, H., Ansell, J."Test for fused-cell origin of tumors with Mus caroli carrying glucose-6-phosphate dehydrogenase cellular mosaicism.". Oncology Reports 7, no. 4 (2000): 897-905. https://doi.org/10.3892/or.7.4.897