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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
Jul-Aug 2000 Volume 7 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Radiation-induced apoptosis: predictive and therapeutic significance in radiotherapy of prostate cancer (review).

M J Szostak, N Kyprianou
Pages: 699-1405
Published online on: 01 July 2000

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Article

HPV-16 E6 oncoprotein induces mutations via p53-dependent and -independent pathways.

H J Kim, W Guo, N H Park
Pages: 707-719
Published online on: 01 July 2000

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Article

Predictive value of cathepsin D and Ki-67 expression at the deepest penetration site for lymph node metastases in gastric cancer.

H Goishi, S Tanaka, K Haruma, M Yoshihara, K Sumii, G Kajiyama, F Shimamoto
Pages: 713-721
Published online on: 01 July 2000

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Article

Percutaneous injection of a low-concentration alkaline solution targeting hepatocellular carcinoma.

T Tamai, T Seki, M Imamura, T Nakagawa, M Wakabayashi, A Nishimura, N Yamashiki, T Shiro, K Inoue, A Okamura, K Harada
Pages: 719-742
Published online on: 01 July 2000

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Article

Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues.

R Yamaguchi, H Yano, Y Nakashima, S Ogasawara, K Higaki, J Akiba, D J Hicklin, M Kojiro
Pages: 725-734
Published online on: 01 July 2000

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Article

Correlation between metastatic potency and the down-regulation of E-cadherin in the mouse hepatoma cell lines G-1 and G-5.

Y Saeki, K Hazeki, M Matsumoto, K Toyoshima, H Akedo, T Seya
Pages: 731-736
Published online on: 01 July 2000

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Article

In vivo enhancement of chemosensitivity of human salivary gland cancer cells by overexpression of TGF-beta stimulated clone-22.

F Omotehara, D Uchida, S Hino, N M Begum, H Yoshida, M Sato, H Kawamata
Pages: 737-777
Published online on: 01 July 2000

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Article

p53 overexpression and K-ras codon 12 mutations in submucosal invasive depressed-type colorectal cancer.

K Saito, K Arai, M Mori
Pages: 741-745
Published online on: 01 July 2000

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Article

Detection of micrometastases in sentinel lymph nodes of the breast applying monoclonal antibodies AE1/AE3 to pancytokeratins.

J H Kowolik, W Kuhn, J Nährig, M Werner, T Obst, N Avril, M Schmitt, H Graeff
Pages: 745-754
Published online on: 01 July 2000

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Article

Antitumor properties of an anti-idiotypic monoclonal antibody in relation to N-glycolyl-containing gangliosides.

A M Vázquez, M R Gabri, A M Hernández, D F Alonso, I Beausoleil, D E Gomez, R Pérez
Pages: 751-757
Published online on: 01 July 2000

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Article

Expression of growth hormone receptor in human liposarcomas and lipomas.

L Temmim, S Kölle, H Baker, F Sinowatz
Pages: 757-817
Published online on: 01 July 2000

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Article

Ocular metastases from breast carcinoma: A multicentric retrospective study.

M Amichetti, O Caffo, E Minatel, M Roncadin, M C Valli, L Lozza, G Panizzoni
Pages: 761-766
Published online on: 01 July 2000

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Article

The utility of tissue harmonic imaging in the liver: a comparison with conventional gray-scale sonography.

K Kubota, N Hisa, T Nishikawa, T Ohnishi, Y Ogawa, S Yoshida
Pages: 767-838
Published online on: 01 July 2000

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Article

Concurrent chemoradiotherapy combined with intraoperative radiotherapy for locally advanced pancreatic cancer: a feasibility study.

M Kokubo, Y Nishimura, Y Shibamoto, K Sasai, R Hosotani, M Imamura, M Hiraoka
Pages: 773-779
Published online on: 01 July 2000

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Article

Evaluation by dual energy X-ray absorptiometry of changed bone density in metastatic bone sites as a consequence of systemic treatment.

A Berruti, L Dogliotti, G Osella, S Cerutti, G Reimondo, A Martino, G Gorzegno, R Catolla, A Angeli
Pages: 777-858
Published online on: 01 July 2000

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Article

Conditions of curability after endoscopic resection for colorectal carcinoma with submucosally massive invasion.

S Tanaka, K Haruma, H Oh-E, S Nagata, Y Hirota, A Furudoi, T Amioka, Y Kitadai, M Yoshihara, F Shimamoto
Pages: 783-791
Published online on: 01 July 2000

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Article

Mutational analysis of transforming growth factor beta receptor type II and DNA mismatch repair genes in sporadic endometrial carcinomas with microsatellite instability.

M Ohwada, M Suzuki, Y Saga, T Suzuki, M Ikeda, M Yamada, I Sato
Pages: 789-881
Published online on: 01 July 2000

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Article

Protein kinase C activity in human gastric carcinoma.

N Uchida, S Okamura, H Kuwano
Pages: 793-799
Published online on: 01 July 2000

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Article

Neoadjuvant intra-arterial infusion chemotherapy combined with hormonal therapy for locally advanced breast cancer.

Y Yuyama, A Yagihashi, K Hirata, T Ohmura, Y Suzuki, J Okamoto, T Yamada, Y Okazaki, Y Watanabe, A Okazaki, K Toda, M Okazaki, T Yajima, H Kameshima, J Araya, N Watanabe
Pages: 797-1598
Published online on: 01 July 2000

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Article

Estrogen-producing ovarian mucinous cystadenomas in postmenopausal women.

K Honda, O Ishiko, K Wakasa, S Kawabata, S Nishimura, S Ogita
Pages: 803-811
Published online on: 01 July 2000

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Article

Subtotal peritonectomy with chemohyperthermic peritoneal perfusion for peritonitis carcinomatosa in gastrointestinal cancer.

T Fujimura, Y Yonemura, H Nakagawara, H Kitagawa, S Fushida, G Nishimura, I Miyazaki, K Shibata
Pages: 809-823
Published online on: 01 July 2000

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Article

A case-control study evaluating occult blood screening for colorectal cancer with hemoccult test and an immunochemical hemagglutination test.

H Saito, Y Soma, M Nakajima, J Koeda, H Kawaguchi, R Kakizaki, R Chiba, T Aisawa, A Munakata
Pages: 815-824
Published online on: 01 July 2000

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Article

Raf-1 kinase activity predicts for paclitaxel resistance in TP53mut, but not TP53wt human ovarian cancer cells.

R A Britten, S Perdue, A Eshpeter, D Merriam
Pages: 821-826
Published online on: 01 July 2000

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Article

Tumor marker and MR imaging criteria for evaluating the efficacy of cyclic balloon-occluded arterial infusion for advanced cancer of the uterine cervix.

O Ishiko, T Sumi, T Yasui, Y Matsumoto, S Ogita, T Kaminou, K Nakamura, R Yamada
Pages: 827-857
Published online on: 01 July 2000

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Article

Expressions of thymidine phosphorylase (dThdPase) and vascular endothelial growth factor on angiogenesis in intestinal-type gastric carcinoma.

T Sakatani, E Okamoto, S Tsujitani, M Ikeguchi, N Kaibara, H Ito
Pages: 831-837
Published online on: 01 July 2000

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Article

Effects of biopsy on lung metastasis.

Y Hioki, M Seto, R Tomoda, T Yamazaki, J Sonoda, A Uchida
Pages: 837-877
Published online on: 01 July 2000

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Article

Immunohistochemical expression of vascular endothelial growth factor can predict response to 5-fluorouracil and cisplatin in patients with gastric adenocarcinoma.

H Takiuchi, I Hirata, S Kawabe, Y Egashira, K Katsu
Pages: 841-847
Published online on: 01 July 2000

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Article

Inhibitory effect of resveratrol on the proliferation of human and rat hepatic derived cell lines.

D Delmas, B Jannin, M Cherkaoui Malki, N Latruffe
Pages: 847-899
Published online on: 01 July 2000

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Article

Evaluation of argyrophilic nucleolar organizer regions (AgNORs) in differentiated thyroid carcinoma as an indicator for disease recurrence.

F Kawasaki, N Onoda, T Ishikawa, Y Ogawa, K Ikeda, S Sugano, Y Kato, K H Chung
Pages: 853-860
Published online on: 01 July 2000

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Article

Establishment of new multidrug-resistant human osteosarcoma cell lines.

Y Oda, Y Matsumoto, K Harimaya, Y Iwamoto, M Tsuneyoshi
Pages: 859-925
Published online on: 01 July 2000

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Article

Clinical significance of mucin staining in keratinizing-type squamous cell carcinoma of the uterine cervix.

Y Matsumoto, O Ishiko, M Deguchi, K Ueda, S Ogita, T Haba, K Wakasa
Pages: 867-876
Published online on: 01 July 2000

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Article

Expression of tissue inhibitor of matrix metalloproteinase-1 in human breast carcinoma.

H Inoue, K Mimori, T Shiraishi, A Kataoka, N Sadanaga, H Ueo, G F Barnard, M Mori
Pages: 871-875
Published online on: 01 July 2000

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Article

Comparison of 5-FU and leucovorin to gemcitabine in the treatment of pancreatic cancer.

B Klein, E Sadikov, M Mishaeli, I Levin, A Figer
Pages: 875-882
Published online on: 01 July 2000

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Article

Expression of soluble urokinase plasminogen activator receptor may be related to outcome in prostate cancer patients.

N P McCabe, F F Angwafo, A Zaher, S H Selman, A Kouinche, J Jankun
Pages: 879-961
Published online on: 01 July 2000

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Article

A phase II evaluation of bexarotene (Targretin) capsules in patients with metastatic melanoma.

A Y Bedikian, C Plager, N Papadopoulos, J Ellerhorst, T Smith, R S Benjamin
Pages: 883-889
Published online on: 01 July 2000

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Article

Left ventricular function in colon cancer patients receiving adjuvant fluoro-folate chemotherapy: an echocardiographic study.

L Balloni, C Porta, S Rossi, A Gola, P Pugliese, S Ferrari, A Bovio, M Danova, A Riccardi
Pages: 887-977
Published online on: 01 July 2000

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Article

Treatment of large cell lymphoma with the Fi2 regimen (doxorubicin, vincristine, cyclophosphamide, bleomycin and prednisone): 25-year experience.

G Bellesi, L Rigacci, G Longo, R Alterini, F Bernardi, A Messori, S Trippoli, M Vaiani, V Carrai, P Rossi Ferrini
Pages: 891-897
Published online on: 01 July 2000

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Article

Test for fused-cell origin of tumors with Mus caroli carrying glucose-6-phosphate dehydrogenase cellular mosaicism.

K Tanaka, A Ootsuyama, H Tanooka, J D Ansell
Pages: 897-905
Published online on: 01 July 2000

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Article

Is reoperation for recurrence of glioblastoma justified?

J Guyotat, F Signorelli, D Frappaz, G Madarassy, A C Ricci, P Bret
Pages: 899-1803
Published online on: 01 July 2000

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Article

Detection of human papillomavirus types 16 and 18 in human neoplastic endometrium: lack of correlation with established prognostic factors.

A Semczuk, A Stenzel, W Baranowski, K Rózynska, M Cybulski, M Kostuch, J Jakowicki, J Wojcierowski
Pages: 905-915
Published online on: 01 July 2000

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Article Open Access

Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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Retraction Open Access

[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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