An in vitro chemosensitivity test for gastric cancer using collagen gel droplet embedded culture.

  • Authors:
    • Y Hanatani
    • H Kobayashi
    • S Kodaira
    • H Takami
    • T Asagoe
    • E Kaneshiro
  • View Affiliations

  • Published online on: September 1, 2000     https://doi.org/10.3892/or.7.5.1027
  • Pages: 1027-1060
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Abstract

Collagen gel droplet embedded culture drug sensitivity test (CD-DST) was applied to 33 patients with gastric cancer (30 primary tumors, 12 metastatic tumors and 25 biopsy specimens). Evaluable rates by CD-DST were 80% for primary tumors, 75% for metastatic tumors and 72% for biopsy specimens. Chemosensitivities of primary tumors were: 5-fluorouracil 25%, mitomycin C 17%, cisplatin 13%, adriamycin 17%, etoposide 21%. Chemosensitivities of metastatic tumors were lower than those of primary tumors. In 4 out of 6 patients who had measurable lesions, clinical responses to chemotherapy were predictable by CD-DST.

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Sep-Oct 2000
Volume 7 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Hanatani Y, Kobayashi H, Kodaira S, Takami H, Asagoe T and Kaneshiro E: An in vitro chemosensitivity test for gastric cancer using collagen gel droplet embedded culture.. Oncol Rep 7: 1027-1060, 2000.
APA
Hanatani, Y., Kobayashi, H., Kodaira, S., Takami, H., Asagoe, T., & Kaneshiro, E. (2000). An in vitro chemosensitivity test for gastric cancer using collagen gel droplet embedded culture.. Oncology Reports, 7, 1027-1060. https://doi.org/10.3892/or.7.5.1027
MLA
Hanatani, Y., Kobayashi, H., Kodaira, S., Takami, H., Asagoe, T., Kaneshiro, E."An in vitro chemosensitivity test for gastric cancer using collagen gel droplet embedded culture.". Oncology Reports 7.5 (2000): 1027-1060.
Chicago
Hanatani, Y., Kobayashi, H., Kodaira, S., Takami, H., Asagoe, T., Kaneshiro, E."An in vitro chemosensitivity test for gastric cancer using collagen gel droplet embedded culture.". Oncology Reports 7, no. 5 (2000): 1027-1060. https://doi.org/10.3892/or.7.5.1027