Platelet-derived endothelial cell growth factor in keratinizing-type squamous cell uterine cervical cancer.

  • Authors:
    • Y Matsumoto
    • O Ishiko
    • M Deguchi
    • S Ogita
    • T Haba
    • K Wakasa
  • View Affiliations

  • Published online on: January 1, 2001     https://doi.org/10.3892/or.8.1.93
  • Pages: 93-100
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Abstract

The purpose of this study was to determine whether intratumor expression of platelet-derived endothelial cell growth factor (PD-ECGF) is a prognostic factor. We examined specimens from 61 cases of carcinoma of uterine cervix (Ca-Cx). Specimens were stained with periodic acid-Schiff preparation with diastase (d-PAS) and alcian blue (pH 2.5) to identify the presence of intracellular mucin. PD-ECGF expression and microvessel count (MVC) were assessed by immunohistochemical staining. Twenty specimens stained positive for mucin. MVC correlated with clinical stage (p<0.01). There was a correlation between PD-ECGF expression and survival time (p<0.05), but no correlation was seen between mucin staining positivity, MVC, and PD-ECGF expression and survival time by the Cox proportional hazard model. Intratumor PD-ECGF expression was not a prognostic factor in keratinizing-type squamous cell carcinoma of the uterine cervix.

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January-February 2001
Volume 8 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Matsumoto Y, Ishiko O, Deguchi M, Ogita S, Haba T and Wakasa K: Platelet-derived endothelial cell growth factor in keratinizing-type squamous cell uterine cervical cancer.. Oncol Rep 8: 93-100, 2001
APA
Matsumoto, Y., Ishiko, O., Deguchi, M., Ogita, S., Haba, T., & Wakasa, K. (2001). Platelet-derived endothelial cell growth factor in keratinizing-type squamous cell uterine cervical cancer.. Oncology Reports, 8, 93-100. https://doi.org/10.3892/or.8.1.93
MLA
Matsumoto, Y., Ishiko, O., Deguchi, M., Ogita, S., Haba, T., Wakasa, K."Platelet-derived endothelial cell growth factor in keratinizing-type squamous cell uterine cervical cancer.". Oncology Reports 8.1 (2001): 93-100.
Chicago
Matsumoto, Y., Ishiko, O., Deguchi, M., Ogita, S., Haba, T., Wakasa, K."Platelet-derived endothelial cell growth factor in keratinizing-type squamous cell uterine cervical cancer.". Oncology Reports 8, no. 1 (2001): 93-100. https://doi.org/10.3892/or.8.1.93