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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
March-April 2001 Volume 8 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-April 2001 Volume 8 Issue 2

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Article

Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model

  • Authors:
    • Ilana Teruszkin Balassiano
    • Sheila Alves de Paulo
    • Nathalie Henriques Silva
    • Maulori Curie Cabral
    • Maria da Gloria da Costa Carvalho

  • View Affiliations / Copyright

    Affiliations: Instituto de Biofisica Carlos Chagas Filho, Laboratorio de Controle da Expressao Genica, Universidade Federal do Rio de Janeiro, Centro de Ciencias da Saude, Bloco C, Rio de Janeiro, Brazil
  • Pages: 431-433
    |
    Published online on: March 1, 2001
       https://doi.org/10.3892/or.8.2.431
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Abstract

Chick embryo chorioallantoic membrane model is a very sensitive assay for studying metastasis in vivo. In this organism, tissue barriers provide a real support to demonstrate the infiltration pathway of two human tumoral cell stains: a line of breast adenocarcinoma (MDA435), and a line of larynx epidermoid carcinoma (Hep2). We studied the metastatic potential of these cells to migrate from the upper chorioallantoic membrane (CAM) to the lower CAM, using as marker a human p53 primer, known for flanking exclusively a human region of exon 8. Our results show that both cell lines possess the ability to migrate from the inoculation site (on the upper CAM) to distant sites of the CAM (lower CAM). A difference in the pattern of migration among the two cell lines was also observed. While Hep2 cells showed a uniform migration from the inoculation site, MDA435 cell line showed a different migration pattern consistent with the idea of two different populations within the same cell line.

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Copy and paste a formatted citation
Spandidos Publications style
Teruszkin Balassiano I, Alves de Paulo S, Henriques Silva N, Curie Cabral M and da Gloria da Costa Carvalho M: Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model. Oncol Rep 8: 431-433, 2001.
APA
Teruszkin Balassiano, I., Alves de Paulo, S., Henriques Silva, N., Curie Cabral, M., & da Gloria da Costa Carvalho, M. (2001). Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model. Oncology Reports, 8, 431-433. https://doi.org/10.3892/or.8.2.431
MLA
Teruszkin Balassiano, I., Alves de Paulo, S., Henriques Silva, N., Curie Cabral, M., da Gloria da Costa Carvalho, M."Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model". Oncology Reports 8.2 (2001): 431-433.
Chicago
Teruszkin Balassiano, I., Alves de Paulo, S., Henriques Silva, N., Curie Cabral, M., da Gloria da Costa Carvalho, M."Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model". Oncology Reports 8, no. 2 (2001): 431-433. https://doi.org/10.3892/or.8.2.431
Copy and paste a formatted citation
x
Spandidos Publications style
Teruszkin Balassiano I, Alves de Paulo S, Henriques Silva N, Curie Cabral M and da Gloria da Costa Carvalho M: Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model. Oncol Rep 8: 431-433, 2001.
APA
Teruszkin Balassiano, I., Alves de Paulo, S., Henriques Silva, N., Curie Cabral, M., & da Gloria da Costa Carvalho, M. (2001). Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model. Oncology Reports, 8, 431-433. https://doi.org/10.3892/or.8.2.431
MLA
Teruszkin Balassiano, I., Alves de Paulo, S., Henriques Silva, N., Curie Cabral, M., da Gloria da Costa Carvalho, M."Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model". Oncology Reports 8.2 (2001): 431-433.
Chicago
Teruszkin Balassiano, I., Alves de Paulo, S., Henriques Silva, N., Curie Cabral, M., da Gloria da Costa Carvalho, M."Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model". Oncology Reports 8, no. 2 (2001): 431-433. https://doi.org/10.3892/or.8.2.431
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