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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2001 Volume 8 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Advanced non-seminomatous germ cell cancer of the testis with brain metastases: Feasibility of additional brain irradiation and whole body hyperthermia plus chemotherapy

Thomas Feyerabend, Gunter Joseph Wiedemann, Richard Steeves
Pages: 219-223
Published online on: 01 March 2001

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Article

A clinical trial of edrecolomab, interleukin-2 and GM-CSF in patients with advanced colorectal cancer

Walter Fiedler, William Kruger, Eckart Laack, Thorsten Mende, Gabi Vohwinkel, Dieter K. Hossfeld
Pages: 225-231
Published online on: 01 March 2001

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Article

Overexpression of human H-ras transgene is responsible for tumors induced by chemical carcinogens in mice

C. Maruyama, M. Tomisawa, S. Wakana, H. Yamazaki, H. Kijima, H. Suemizu, Y. Ohnishi, K. Urano, K. Hioki, T. Usui, M. Nakamura, T. Tsuchida, K. Mitsumori, T. Nomura, N. Tamaoki, Y. Ueyama
Pages: 233-237
Published online on: 01 March 2001

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Article

Prognostic value of thymidine phosphorylase immunostaining in patients with uterine cervical cancer treated concurrently with doxifluridine, radiotherapy and immunotherapy

S. Sato, A. Yajima, H. Sasaki, K. Mizutani, H. Honjo, K. Yamamoto, M. Ozaki, K. Hasegawa, T. Kudo, M. Yakushiji, M. Hatae, K. Noda
Pages: 239-244
Published online on: 01 March 2001

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Article

Presence of Streptococcus infection in extra-oropharyngeal head and neck squamous cell carcinoma and its implication in carcinogenesis

K. Shiga, M. Tateda, S. Saijo, T. Hori, I. Sato, H. Tateno, K. Matsuura, T. Takasaka, T. Miyagi
Pages: 245-248
Published online on: 01 March 2001

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Article

Expression of E-cadherin and β-catenin in primary and peritoneal metastatic ovarian carcinoma

Toru Fujioka, Yuji Takebayashi, Toshimasa Kihana, Yasuki Kusanagi, Katsuyuki Hamada, Hiroshi Ochi, Takahumi Uchida, Manabu Fukumoto, Masaharu Ito
Pages: 249-255
Published online on: 01 March 2001

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Article

Changes in mucosal immune cells of bladder tumor patient after BCG intravesical immunotherapy

Sung-Goo Chang, Sun-Ju Lee, Jung-Sik Huh, Ju-Hie Lee
Pages: 257-261
Published online on: 01 March 2001

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Article

Clinicopathologic study on cholangiolocellular carcinoma

Koji Shiota, Jun Taguchi, Osamu Nakashima, Miwako Nakashima, Masamichi Kojiro
Pages: 263-268
Published online on: 01 March 2001

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Article

Prevalence of silent prostatic adenocarcinoma in 165 patients undergone cystoprostatectomy: A retrospective study

L. Cindolo, G. Benincasa, R. Autorino, S. Domizio, G. De Rosa, G. Testa, M. D'Armiento, V. Altieri
Pages: 269-271
Published online on: 01 March 2001

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Article

Effects of concomitant use of doxifluridine, radiotherapy and immunotherapy in patients with advanced cervical cancer

Kaichiro Yamamoto, Kiichiro Noda, Masayuki Hatae, Takafumi Kudo, Kazuo Hasegawa, Ryuichiro Nishimura, Hideo Honjo, Akira Yajima, Shinji Sato, Katsumi Mizutani, Michiaki Yakushiji, Yoshiteru Terashima, Kazunori Ochiai, Hiroshi Sasaki, Masami Ozaki
Pages: 273-277
Published online on: 01 March 2001

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Article

Cisplatin-based chemotherapy for postoperative recurrence in non-small cell lung cancer patients: Relation of the in vitro chemosensitive test to clinical response

Masahiko Higashiyama, Ken Kodama, Hideoki Yokouchi, Koji Takami, Hidemitsu Nakagawa, Fumio Imamura, Kazuhiko Minamigawa, Hisayuki Kobayashi
Pages: 279-283
Published online on: 01 March 2001

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Article

A pilot study of paclitaxel and carboplatin for recurrent ovarian cancer

Susumu Adachi, Toshitada Ogasawara, Kimihiko Ito, Masayasu Koyama, Tadayoshi Nagano, Akira Suzuki, Toshio Yamada, Yoshinori Nakata, Mitsuru Ozawa
Pages: 285-288
Published online on: 01 March 2001

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Article

c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma

T. Hiyama, K. Haruma, Y. Kitadai, M. Ito, H. Masuda, M. Miyamoto, S. Tanaka, M. Yoshihara, K. Sumii, F. Shimamoto, K. Chayama
Pages: 289-292
Published online on: 01 March 2001

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Article

Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after helicobacter pylori eradication

T. Hiyama, K. Haruma, Y. Kitadai, M. Ito, H. Masuda, M. Miyamoto, S. Tanaka, M. Yoshihara, K. Sumii, F. Shimamoto, K. Chayama
Pages: 293-297
Published online on: 01 March 2001

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Article

Microsatellite instability of each tumor in sporadic synchronous multiple colorectal cancers

Y. Abe, H. Masuda, R. Okubo
Pages: 299-304
Published online on: 01 March 2001

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Article

Topical Biafine and Lipiderm for the prevention of radiation dermatitis: A randomized prospective trial

Eyal Fenig, Baruch Brenner, Alan Katz, Jaqueline Sulkes, Moshe Lapidot, Jacob Schachter, Hana Malik, Aaron Sulkes, Haim Gutman
Pages: 305-309
Published online on: 01 March 2001

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Article

Plasma soluble Fas ligand concentration: Decrease in elderly men and increase in patients with gastric carcinoma

Takashi Ichikura, Takashi Majima, Takefumi Uchida, Eiji Okura, Toshiya Ogawa, Hidetaka Mochizuki
Pages: 311-314
Published online on: 01 March 2001

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Article

Postoperative radiotherapy for squamous cell carcinoma of the maxillary sinus: Analysis of local control and late complications

K. Ogawa, T. Toita, Y. Kakinohana, G. Adachi, S. Kojya, T. Itokazu, A. Shinhama, J. Matsumura, S. Murayama
Pages: 315-319
Published online on: 01 March 2001

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Article

Effectiveness of activated vitamin D3 on improving prognosis of osteosarcoma patients

T. Nozaki, K. Kusuzaki, H. Takeshita, S. Nakamura, S. Hashiguchi, H. Murata, Y. Hirasawa
Pages: 321-324
Published online on: 01 March 2001

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Article

Insulin-like growth factor-I receptor antagonism results in increased cytotoxicity of breast cancer cells to doxorubicin and taxol

Derrick J. Beech, Nimisha Parekh, Ying Pang
Pages: 325-329
Published online on: 01 March 2001

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Article

A hepatocellular carcinoma with lymph node metastasis and invasion into the gallbladder: Preoperative difficulty ruling out a gallbladder carcinoma

N. Ueno, T. Kanamaru, K. Kawaguchi, K.-I. Tanaka, K. Inoue, Y. Idei, M. Yamamoto
Pages: 331-335
Published online on: 01 March 2001

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Article

Whole body 18F-2-deoxyglucose positron emission tomography to restage non-small cell lung cancer

S.-P. Changlai, S.-C. Tsai, M.-C. Chou, Y.-J. Ho, C.-H. Kao
Pages: 337-339
Published online on: 01 March 2001

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Article

Long-term results of a phase-II-pilot trial on preoperative high-dose chemotherapy with stem cell rescue in patients with cancer of the upper gastrointestinal tract

Wolfgang E. Berdel, Torsten Heldmann, Eckhard Thiel
Pages: 341-342
Published online on: 01 March 2001

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Case Report

Multiple gastric carcinoid tumors with type A gastritis concomitant with gastric cancer: A case report

Minoru Kitago, Takao Inada, Seiji Igarashi, Satoshi Mizutani, Yoshiro Ogata, Tetsuro Kubota
Pages: 343-346
Published online on: 01 March 2001

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Article

Gene expression of human squamous cell carcinoma antigens 1 and 2 in human cell lines

Katsuyuki Hamada, Yasushi Hanakawa, Koji Hashimoto, Mari Iwamoto, Toshimasa Kihana, Susumu Hirose, Masahiko Nakamura, Masaharu Ito
Pages: 347-354
Published online on: 01 March 2001

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Article

Prediction of radiosensitivity in human esophageal squamous cell carcinomas with heme oxygenase-1: a clinicopathological and immunohistochemical study

S. Yokoyama, S. Mita, A. Okabe, M. Abe, M. Ogawa
Pages: 355-358
Published online on: 01 March 2001

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Article

Anti-invasive activity of torilin, a sesquiterpene compound isolated from Torilis japonica

Myoung Sook Kim, Jin Hyen Baek, Moon-Taek Park, Tae-Kwon Sohn, Se Eun Kim, Jung Joon Lee, Kyu-Won Kim
Pages: 359-364
Published online on: 01 March 2001

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Article

Extra-articular wide tumor resection and limb reconstruction in malignant bone tumors invading the knee joint

S. Nakamura, K. Kusuzaki, H. Murata, H. Takeshita, M. Hirata, S. Hashiguchi, Y. Hirasawa
Pages: 365-368
Published online on: 01 March 2001

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Article

Expression of the SART1 tumor-rejection antigen in hepatocellular carcinomas

S. Yutani, S. Shichijo, Y. Inoue, N. Kawagoe, K. Okuda, T. Kurohiji, M. Tanaka, M. Sata, K. Itoh
Pages: 369-372
Published online on: 01 March 2001

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Article

Effects of acute and chronic body weight gain reductions in the evaluation of agents for efficacy in mammary cancer prevention

Cristina Rodriguez-Burford, Ronald A. Lubet, Vernon E. Steele, Isao Eto, Mattie Bandy, M. Margaret Juliana, Heidi L. Weiss, William E. Grizzle, Gary J. Kelloff, Clinton J. Grubbs
Pages: 373-379
Published online on: 01 March 2001

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Article

Low dose carboplatin (AUC 4.5) combined with vinorelbine in the treatment of advanced non-small cell lung cancer: A single institution phase II study

S. Bretti, E. Manzin, A. Celano, G. Ritorto, C. Loddo, A. Berruti
Pages: 381-385
Published online on: 01 March 2001

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Article

Evaluation of epidermal growth factor receptor, carcinoembryonic antigen and Lewis carbohydrate antigens in human colorectal and liver neoplasias

A. Di Carlo, A. Mariano, V. D'Alessandro, G. Belli, G. Romano, V. Macchia
Pages: 387-392
Published online on: 01 March 2001

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Article

Microsatellite instability as biomarker for risk of multiple primary malignancies of the upper aerodigestive tract

Iacopo Sardi, Alessandro Franchi, Corso Bocciolini, Claudia Mechi, Aimo Frittelli, Luca Bruschini, Oreste Gallo
Pages: 393-399
Published online on: 01 March 2001

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Article

Clinical significance of MT1-MMP mRNA expression in breast cancer

K. Mimori, H. Ueo, C. Shirasaka, M. Mori
Pages: 401-403
Published online on: 01 March 2001

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Article

Circulating levels of endostatin in cancer patients

Katsumasa Kuroi, C. Tanaka, Masakazu Toi
Pages: 405-409
Published online on: 01 March 2001

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Article

Natural course of cavernous hepatic hemangioma

Hiroshi Okano, Katsuya Shiraki, Hidekazu Inoue, Takeshi Ito, Takenari Yamanaka, Masatoshi Deguchi, Kazushi Sugimoto, Takahisa Sakai, Shigeru Ohmori, Kazumoto Murata, Koujiro Takase, Takeshi Nakano
Pages: 411-414
Published online on: 01 March 2001

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Article

Interleukin-6 and its relationships to acute phase proteins in serous effusion differentiation

Michael G. Alexandrakis, Despina S. Kyriakou, Demosthenes Bouros, Irene Xylouri, Nikolaos Antonakis, Nikolaos M. Siafakas
Pages: 415-420
Published online on: 01 March 2001

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Article

Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitors in stage II non-small cell lung cancer: Implications for MMP inhibition therapy

Stuart C. Pritchard, Marianne C. Nicolson, Celine Lloret, Judith A. McKay, Valerie G. Ross, Keith M. Kerr, Graeme I. Murray, Howard L. McLeod
Pages: 421-424
Published online on: 01 March 2001

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Article

IFNα 2b induces apoptosis and proteasome-mediated degradation of p27Kip1 in a human lung cancer cell line

Alejandro Moro, Silvio E. Perea, Cristina Pantoja, Alicia Santos, Manuel De J. Arana, Manuel Serrano
Pages: 425-429
Published online on: 01 March 2001

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Article

Metastatic potential of MDA435 and Hep2 cell lines in chorioallantoic membrane (CAM) model

Ilana Teruszkin Balassiano, Sheila Alves de Paulo, Nathalie Henriques Silva, Maulori Curie Cabral, Maria da Gloria da Costa Carvalho
Pages: 431-433
Published online on: 01 March 2001

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Article

Comparative effects of dimethylbenz(a)anthacene and a 15% olive-oil diet on cellular components and expression of apoptosis-related proteins in the spleen and mammary gland tumors of rats

G. Kossoy, G. Yarden, H. Ben-Hur, N. Kossoy, A. Stark, Z. Madar, I. Zusman
Pages: 435-439
Published online on: 01 March 2001

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Article

Application of an adapted international prognostic index for aggressive non-Hodgkin's lymphomas: Good discrimination and lower survival rates in Rio de Janeiro, Brazil

Irene Biasoli, Jose Carlos Morais, Patricia Soares de Jesus, Wolmar Pulcheri, Marcio Nucci, Nelson Spector
Pages: 441-444
Published online on: 01 March 2001

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Article

Effects of antiprogestins RU486 and ZK98299 on the expression of cell cycle proteins of a medroxyprogesterone acetate (MPA)-induced murine mammary tumor

Maria Giselle Peters, Silvia Vanzulli, Patricia V. Elizalde, Eduardo H. Charreau, Maria Mercedes Goin
Pages: 445-449
Published online on: 01 March 2001

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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April-2026 Volume 55 Issue 4

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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