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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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July-August 2001 Volume 8 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-August 2001 Volume 8 Issue 4

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Article

Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression

  • Authors:
    • Hirotoshi Yonemasu
    • Masaki Takashima
    • Ken-Ichi Nishiyama
    • Takashi Ueki
    • Takashi Yao
    • Masao Tanaka
    • Masazumi Tsuneyoshi

  • View Affiliations / Copyright

    Affiliations: Department of Anatomic Pathology, Kyushu University, Fukuoka, Japan
  • Pages: 745-752
    |
    Published online on: July 1, 2001
       https://doi.org/10.3892/or.8.4.745
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Abstract

The characteristics of undifferentiated (anaplastic) carcinoma (UC) of the pancreas were analysed and compared with those of poorly differentiated adenocarcinoma (PA). Eight cases of UC of the pancreas were evaluated by clinicopathological and immunohistochemical methods and compared with 20 cases of PA. Large size of the tumor, local invasion and lymph node metastasis were frequently seen in UC, leading to a significantly worse prognosis compared to that of PA (p=0.022). Immunohistochemically, E-cadherin expression was completely lost in 7/8 UC cases, whereas half the PA cases revealed a strong reactivity for E-cadherin. α- and β-catenin expressions tended to be impaired in UC compared with PA. The results suggest that the altered expression of adhesion molecules is correlated with dedifferentiated change and is contributory to its aggressive biological behaviour.

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Copy and paste a formatted citation
Spandidos Publications style
Yonemasu H, Takashima M, Nishiyama K, Ueki T, Yao T, Tanaka M and Tsuneyoshi M: Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression. Oncol Rep 8: 745-752, 2001.
APA
Yonemasu, H., Takashima, M., Nishiyama, K., Ueki, T., Yao, T., Tanaka, M., & Tsuneyoshi, M. (2001). Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression. Oncology Reports, 8, 745-752. https://doi.org/10.3892/or.8.4.745
MLA
Yonemasu, H., Takashima, M., Nishiyama, K., Ueki, T., Yao, T., Tanaka, M., Tsuneyoshi, M."Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression". Oncology Reports 8.4 (2001): 745-752.
Chicago
Yonemasu, H., Takashima, M., Nishiyama, K., Ueki, T., Yao, T., Tanaka, M., Tsuneyoshi, M."Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression". Oncology Reports 8, no. 4 (2001): 745-752. https://doi.org/10.3892/or.8.4.745
Copy and paste a formatted citation
x
Spandidos Publications style
Yonemasu H, Takashima M, Nishiyama K, Ueki T, Yao T, Tanaka M and Tsuneyoshi M: Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression. Oncol Rep 8: 745-752, 2001.
APA
Yonemasu, H., Takashima, M., Nishiyama, K., Ueki, T., Yao, T., Tanaka, M., & Tsuneyoshi, M. (2001). Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression. Oncology Reports, 8, 745-752. https://doi.org/10.3892/or.8.4.745
MLA
Yonemasu, H., Takashima, M., Nishiyama, K., Ueki, T., Yao, T., Tanaka, M., Tsuneyoshi, M."Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression". Oncology Reports 8.4 (2001): 745-752.
Chicago
Yonemasu, H., Takashima, M., Nishiyama, K., Ueki, T., Yao, T., Tanaka, M., Tsuneyoshi, M."Phenotypical characteristics of undifferentiated carcinoma of the pancreas: A comparison with pancreatic ductal adenocarcinoma and relevance of E-cadherin, α catenin and β catenin expression". Oncology Reports 8, no. 4 (2001): 745-752. https://doi.org/10.3892/or.8.4.745
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