A case of undifferentiated carcinoma of the gallbladder with anomalous arrangement of the pancreaticobiliary ductal system

Yano,Yoshihiko; Tasaka,Katsumi; Okutani,Toshio; Maeda,Yuichiro; Mori,Toshiyuki; Tamura,Miho; Hamada,Yasuhiro; Yokoyama,Tomoko; Maeda,Naomi; Tomofuji,Yoshinobu; Morishita,Toru; Sugihara,Jun-Ichi; Chinzei,Tadanobu

doi:10.3892/or.8.6.1281

November-December 2001 Volume 8 Issue 6

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November-December 2001 Volume 8 Issue 6

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Article

A case of undifferentiated carcinoma of the gallbladder with anomalous arrangement of the pancreaticobiliary ductal system

Authors:
- Yoshihiko Yano
- Katsumi Tasaka
- Toshio Okutani
- Yuichiro Maeda
- Toshiyuki Mori
- Miho Tamura
- Yasuhiro Hamada
- Tomoko Yokoyama
- Naomi Maeda
- Yoshinobu Tomofuji
- Toru Morishita
- Jun-Ichi Sugihara
- Tadanobu Chinzei
View Affiliations / Copyright

Affiliations: Division of Diabetes, Digestive and Kidney Diseases, Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Chuo-ku, Kobe 650-0017, Japan
Pages: 1281-1283
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Published online on: November 1, 2001

https://doi.org/10.3892/or.8.6.1281
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Abstract

Anomalous junction of the pancreaticobiliary duct (AJPBD) is a congenital anomaly associated with gallbladder carcinoma. Especially patients with noncystic dilatation and without dilatation of the biliary tract are at risk of gallbladder carcinoma. A 56-year-old woman with advanced gallbladder cancer associated with AJPBD but without dilatation of the biliary tract was treated at our hospital. Although histologically cancer cells remained in the layer of the proprial mucosa, extensive metastases to lymph nodes including the paraaorta and peripancreas were detected. According to the TNM classification this case was of Stage IVB. The cancer consisted of medullary round cells, and was diagnosed as undifferentiated carcinoma. After surgery poor prognosis was expected, but three years have elapsed with no recurrence. The case is of interest because of two points of discrepancy: the primary cancer did not show deep invasion but demonstrated extensive lymph node metastases; the cancer was histologically malignant but prognosis was relatively good.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

A case of undifferentiated carcinoma of the gallbladder with anomalous arrangement of the pancreaticobiliary ductal system

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Abstract

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