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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-December 2001 Volume 8 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Genetic instability and the evolution of angiogenic tumor cell lines (Review)

Dominik Wodarz, David C. Krakauer
Pages: 1195-1201
Published online on: 01 November 2001

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Article

Signaling molecules implicated in heregulin induction of growth arrest and apoptosis

Fabiana K. Guerra-Vladusic, Esteban A. Vladusic, M.-S. Tsai, R. Lupu
Pages: 1203-1214
Published online on: 01 November 2001

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Article

Overexpression of the p53 gene product in canine mammary tumors

Satomi Haga, Masanari Nakayama, Kouko Tatsumi, Manabu Maeda, Shunsuke Imai, Seiich Umesako, Hiroshi Yamamoto, Jo Hilgers, Nurul H. Sarkar
Pages: 1215-1219
Published online on: 01 November 2001

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Article

Up-regulation of neuroendocrine differentiation in prostate cancer after androgen deprivation therapy, degree and androgen independence

Takaaki Ito, Shinya Yamamoto, Yoshio Ohno, Kazunori Namiki, Taku Aizawa, Akihito Akiyama, Masaaki Tachibana
Pages: 1221-1224
Published online on: 01 November 2001

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Article

Cyclooxygenase-2 expression in malignant mesenchymal tumors and related uterine lesions

Y. Matsumoto, O. Ishiko, T. Sumi, H. Yoshida, M. Deguchi, E. Nakagawa, T. Haba, K. Wakasa, S. Ogita, Y. Ando
Pages: 1225-1227
Published online on: 01 November 2001

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Article

Genetic imbalances in preinvasive tissue of hypopharynx provide evidence for cytogenetic heterogeneity

Helmut Steinhart, Jorg E. Bohlender, Jannis Constantinidis, Stefanie Urbschat, Ulrike Fischer, Heinrich Iro, Stefan Pahl, Eckart Meese
Pages: 1229-1231
Published online on: 01 November 2001

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Article

Fhit protein expression in human gastric cancer and related precancerous lesions

Michele Caselli, Marco Marchisio, Michele Gaudio, Luca Saragoni, Giovanni Lanza, Vittorio Alvisi, Valeria Bertagnolo, Manuela Concu, Silvano Capitani, Elisabetta Caramelli
Pages: 1233-1237
Published online on: 01 November 2001

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Article

Splenic metastasis of lung cancer

Hiroaki Satoh, Koichi Watanabe, Hiroichi Ishikawa, Yuko T. Yamashita, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 1239-1241
Published online on: 01 November 2001

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Article

Primary peritoneal clear cell carcinoma: excellent results from paclitaxel and carboplatin combination chemotherapy

T. Ichimura, O. Ishiko, S. Nishimura, T. Kojima, K. Shimura
Pages: 1243-1245
Published online on: 01 November 2001

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Article

Over-expression of vascular endothelial growth factor after preoperative radiation therapy for rectal cancer

Mutsumi Nozue, Naohide Isaka, Katashi Fukao
Pages: 1247-1249
Published online on: 01 November 2001

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Article

Lung cancer patients with cardio- and cerebrovascular diseases

Koichi Kurishima, Hiroaki Satoh, Hiroichi Ishikawa, Yuko T. Yamashita, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 1251-1253
Published online on: 01 November 2001

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Article

Transient shrinkage of a uterine leiomyosarcoma treated with GnRH agonist for a presumed uterine leiomyoma: Comparison of magnetic resonance imaging finding before and during GnRH agonist treatment

Naoki Kawamura, Naoko Iwanaga, Sachiko Hada, Kyoko Maeda, Toshiyuki Sumi, Osamu Ishiko, Sachio Ogita
Pages: 1255-1257
Published online on: 01 November 2001

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Article

Association between overexpression of cyclooxygenase-2 and suppression of apoptosis in advanced cancer of the uterine cervix after cyclic balloon-occluded arterial infusion

O. Ishiko, T. Sumi, H. Yoshida, Y. Matsumoto, K.-I. Honda, M. Deguchi, R. Yamada, S. Ogita
Pages: 1259-1263
Published online on: 01 November 2001

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Article

Clinical significance of urinary vascular endothelial growth factor in patients with superficial bladder tumors

Sung-Hyun Jeon, Sun-Ju Lee, Sung-Goo Chang
Pages: 1265-1267
Published online on: 01 November 2001

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Article

Pharmacokinetics and pharmacodynamics of serum platinum of gynecologic cancer patients treated with nedaplatin

Y. Matsumoto, O. Ishiko, E. Nakagawa, T. Sumi, Y. Hyun, Y. Ando, S. Ogita
Pages: 1269-1273
Published online on: 01 November 2001

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Article

Immunohistochemical findings of nitric oxide synthase expression in urothelial transitional cell carcinoma including dysplasia

H. Hayashi, M. Kuwahara, N. Fujisaki, M. Furihata, Y. Ohtsuki, S. Kagawa
Pages: 1275-1279
Published online on: 01 November 2001

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Article

A case of undifferentiated carcinoma of the gallbladder with anomalous arrangement of the pancreaticobiliary ductal system

Yoshihiko Yano, Katsumi Tasaka, Toshio Okutani, Yuichiro Maeda, Toshiyuki Mori, Miho Tamura, Yasuhiro Hamada, Tomoko Yokoyama, Naomi Maeda, Yoshinobu Tomofuji, Toru Morishita, Jun-Ichi Sugihara, Tadanobu Chinzei
Pages: 1281-1283
Published online on: 01 November 2001

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Article

Expression and cisplatin sensitivity of copper-transporting P-type adenosine triphosphatase (ATP7B) in human solid carcinoma cell lines

Kentaro Nakayama, Kohji Miyazaki, Atsuko Kanzaki, Manabu Fukumoto, Yuji Takebayashi
Pages: 1285-1287
Published online on: 01 November 2001

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Article

Fibronectin gene polymorphism in patients with lung cancer

Krzysztof Siemianowicz, Jan Gminski, Tomasz Francuz, Marcin Syzdol, Dorota Polanska, Marek Machalski, Krzysztof Brulinski, Helena Magiera-Molendowska
Pages: 1289-1292
Published online on: 01 November 2001

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Article

Proximal gastrectomy and jejunal pouch interposition: Evaluation of postoperative symptoms and gastrointestinal hormone secretion

Tsuyoshi Hoshikawa, Ryuichi Denno, Hideki Ura, Kouji Yamaguchi, Koichi Hirata
Pages: 1293-1299
Published online on: 01 November 2001

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Article

Fibroblast growth factor receptor 3 S249C mutation in virus associated squamous cell carcinomas

Vorasuk Shotelersuk, Chupong Ittiwut, K. Shotelersuk, S. Triratanachat, Yong Poovorawan, Apiwat Mutirangura
Pages: 1301-1304
Published online on: 01 November 2001

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Article

Peritoneal carcinomatosis in lung cancer patients

Hiroaki Satoh, Hiroichi Ishikawa, Yuko T. Yamashita, Koichi Kurishima, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 1305-1307
Published online on: 01 November 2001

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Article

Probucol decreases total body fat loss in VX2-carcinoma-induced cachectic rabbits

Y. Hyun, O. Ishiko, K.-I. Honda, K. Hirai, T. Sumi, K. Hattori, E. Nakagawa, T. Yasui, S. Nishimura, S. Ogita
Pages: 1309-1311
Published online on: 01 November 2001

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Article

Obstructing carcinomas of the colon and rectum have a smaller size compared with those of non-obstructing carcinomas

T. Nozoe, M. Yasuda, M. Honda, S. Inutsuka, D. Korenaga
Pages: 1313-1315
Published online on: 01 November 2001

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Article

Expression of angiogenic factors in extrapelvic endometriosis

Masaaki Deguchi, Osamu Ishiko, Toshiyuki Sumi, Hiroyuki Yoshida, Kumio Yamamoto, Sachio Ogita
Pages: 1317-1319
Published online on: 01 November 2001

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Article

Cyclooxygenase-2 level and culture conditions influence NS398-induced apoptosis and caspase activation in lung cancer cells

Hui-Chiu Chang, Ching-Feng Weng
Pages: 1321-1325
Published online on: 01 November 2001

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Article

Long-term effect and tolerance of talc slurry for control of malignant pleural effusions

Alain Prevost, Brigitte Costa, Rachid Elamarti, Pierre Nazeyrollas, Frederique Mallet, Gabriel Yazbek, Adela Cauchois
Pages: 1327-1331
Published online on: 01 November 2001

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Article

Absence of Bcl10 gene mutations in Ewing's sarcomas

Yong-Koo Park, Sung-Gil Chi, K. Krishnan Unni
Pages: 1333-1335
Published online on: 01 November 2001

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Article

In vivo and in vitro nuclear magnetic resonance spectroscopy investigation of an intracranial mass

M. R. Tosi, R. Ricci, G. Bottura, V. Tugnoli
Pages: 1337-1339
Published online on: 01 November 2001

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Article

Prevention of the development of preneoplastic lesions, aberrant crypt foci, by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male F344 rats

H. Lu, T. Uesaka, O. Katoh, E. Kyo, H. Watanabe
Pages: 1341-1345
Published online on: 01 November 2001

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Article

Evaluation of the c-Met immunostain to detect malignant cells in body cavity effusions

Robert L. Zimmerman, Franz Fogt
Pages: 1347-1350
Published online on: 01 November 2001

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Article

Plasma and tissue prolactin detection in colon carcinoma

M. Indinnimeo, C. Cicchini, L. Memeo, A. Stazi, C. Ghini, F. Ricci, M. G. Reale, P. Mingazzini
Pages: 1351-1353
Published online on: 01 November 2001

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Article

Livistona extract inhibits angiogenesis and cancer growth

Maryam R. Sartippour, Canhui Liu, Zhi-Ming Shao, Vay Liang Go, David Heber, Mai Nguyen
Pages: 1355-1357
Published online on: 01 November 2001

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Article

Inactivation of the p16INK4A gene by methylation is not a frequent event in sporadic ovarian carcinoma

Iain Brown, Benedict J. Milner, Patrick H. Rooney, Neva E. Haites
Pages: 1359-1362
Published online on: 01 November 2001

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Article

Characterization of anti-BRCA2 antibodies in cell lines by Western blot analysis

D. Bernard-Gallon, L. Cravello, C. Vissac, Y.-J. Bignon
Pages: 1363-1366
Published online on: 01 November 2001

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Article

ELISA-based Ki-ras gene mutation analyses in pancreatic and cholangiocarcinoma cells and tissues

Marcin Gabriel, Doris Henne-Bruns, Holger Kalthoff
Pages: 1367-1370
Published online on: 01 November 2001

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Article

Chemoimmunotherapy of cancer: potentiated effectiveness of granulocyte-macrophage colony-stimulating factor and ifosfamide derivative CBM-4A

M. Indrova, J. Bubenik, J. Simova, J. Bieblova, T. Jandlova, M. Smahel, V. Vonka, H. Glazman-Kusnierczyk, E. Pajtasz-Piasecka, C. Radzikowski, R. Mikyskova
Pages: 1371-1374
Published online on: 01 November 2001

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Article

Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas

Thilo Papp, Holger Schipper, Heidi Pemsel, Marcus Unverricht, Klaus-Michael Muller, Thorsten Wiethege, Dietmar Schiffmann, Qamar Rahman
Pages: 1375-1379
Published online on: 01 November 2001

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Article

Modulation of soluble CD44 concentrations by hormone and anti-hormone treatment in gynecological tumor cell lines

Elmar Stickeler, Suwanit Therasakvichya, Volker J. Moebus, Dirk G. Kieback, Ingo B. Runnebaum, Rolf Kreienberg
Pages: 1381-1386
Published online on: 01 November 2001

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Article

Effects of a 15% orange-pulp diet on tumorigenesis and immune response in rats with colon tumors

G. Kossoy, H. Ben-Hur, A. Stark, I. Zusman, Z. Madar
Pages: 1387-1391
Published online on: 01 November 2001

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Article

Comparison of 18FDG-PET with CT scans in the evaluation of patients with residual and recurrent Hodgkin's lymphoma

H. Dittmann, M. Sokler, C. Kollmannsberger, B. M. Dohmen, C. Baumann, A. Kopp, R. Bares, C. D. Claussen, L. Kanz, C. Bokemeyer
Pages: 1393-1399
Published online on: 01 November 2001

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Article

Predictive value of altered p27Kip1 and p21WAF/Cip1 protein expression for the clinical prognosis of patients with localized prostate cancer

M. A. Kuczyk, C. Bokemeyer, J. Hartmann, J. Schubach, C. Walter, S. Machtens, R. Knuchel, C. Kollmannsberger, U. Jonas, J. Serth
Pages: 1401-1407
Published online on: 01 November 2001

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Article

Upregulation of non-mutated H-ras and its upstream and downstream signaling proteins in colorectal cancer

J. Feng, F. Hua, R. Shuo, G. Chongfeng, X. Huimian, T. Nakajima, W. Subao, N. Tsuchida
Pages: 1409-1413
Published online on: 01 November 2001

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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