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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November-December 2001 Volume 8 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November-December 2001 Volume 8 Issue 6

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Article

Long-term effect and tolerance of talc slurry for control of malignant pleural effusions

  • Authors:
    • Alain Prevost
    • Brigitte Costa
    • Rachid Elamarti
    • Pierre Nazeyrollas
    • Frederique Mallet
    • Gabriel Yazbek
    • Adela Cauchois

  • View Affiliations / Copyright

    Affiliations: Institut Jean-Godinot, Service Chirurgie, 51056 Reims Cedex, France
  • Pages: 1327-1331
    |
    Published online on: November 1, 2001
       https://doi.org/10.3892/or.8.6.1327
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Abstract

Drainage of malignant pleural effusions (MPE) by thoracocenthesis and subsequent pleurodesis is an established means of symptomatic relief in terminally-ill patients, but the optimal therapy remains unclear. Among many sclerosing agent, talc is the most widely used, but its intrapleural administration and dosage have not been clearly determined. To assess the efficacy of using talc slurry with high dose (8 g) as a sclerosing agent instilled into the pleural space at the patient bedside, we carried out a study in 31 patients suffering from symptomatic MPE, followed until death or up to 1 year with radiographs. Patients were evaluated for immediate tolerance (31 patients), and for efficacy and long-term tolerance (27 patients) of the talc therapy. We have shown, that pleurodesis was satisfactory in 22/27 patients (81.4%). This result appeared comparable with other series. Moreover, we observed a long-lasting efficacy: within 6 months and within 12 months after talc instillations, 20/20 patients and 9/9 patients respectively were symphysed with efficacy. Complications related to talc (8 g) were rare and moderate (pain, fever). Taking into account some technical aspects of talc instillation for good performance of the therapy, we recommend this method as the optimal route of administration.

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Copy and paste a formatted citation
Spandidos Publications style
Prevost A, Costa B, Elamarti R, Nazeyrollas P, Mallet F, Yazbek G and Cauchois A: Long-term effect and tolerance of talc slurry for control of malignant pleural effusions. Oncol Rep 8: 1327-1331, 2001.
APA
Prevost, A., Costa, B., Elamarti, R., Nazeyrollas, P., Mallet, F., Yazbek, G., & Cauchois, A. (2001). Long-term effect and tolerance of talc slurry for control of malignant pleural effusions. Oncology Reports, 8, 1327-1331. https://doi.org/10.3892/or.8.6.1327
MLA
Prevost, A., Costa, B., Elamarti, R., Nazeyrollas, P., Mallet, F., Yazbek, G., Cauchois, A."Long-term effect and tolerance of talc slurry for control of malignant pleural effusions". Oncology Reports 8.6 (2001): 1327-1331.
Chicago
Prevost, A., Costa, B., Elamarti, R., Nazeyrollas, P., Mallet, F., Yazbek, G., Cauchois, A."Long-term effect and tolerance of talc slurry for control of malignant pleural effusions". Oncology Reports 8, no. 6 (2001): 1327-1331. https://doi.org/10.3892/or.8.6.1327
Copy and paste a formatted citation
x
Spandidos Publications style
Prevost A, Costa B, Elamarti R, Nazeyrollas P, Mallet F, Yazbek G and Cauchois A: Long-term effect and tolerance of talc slurry for control of malignant pleural effusions. Oncol Rep 8: 1327-1331, 2001.
APA
Prevost, A., Costa, B., Elamarti, R., Nazeyrollas, P., Mallet, F., Yazbek, G., & Cauchois, A. (2001). Long-term effect and tolerance of talc slurry for control of malignant pleural effusions. Oncology Reports, 8, 1327-1331. https://doi.org/10.3892/or.8.6.1327
MLA
Prevost, A., Costa, B., Elamarti, R., Nazeyrollas, P., Mallet, F., Yazbek, G., Cauchois, A."Long-term effect and tolerance of talc slurry for control of malignant pleural effusions". Oncology Reports 8.6 (2001): 1327-1331.
Chicago
Prevost, A., Costa, B., Elamarti, R., Nazeyrollas, P., Mallet, F., Yazbek, G., Cauchois, A."Long-term effect and tolerance of talc slurry for control of malignant pleural effusions". Oncology Reports 8, no. 6 (2001): 1327-1331. https://doi.org/10.3892/or.8.6.1327
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