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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
November-December 2002 Volume 9 Issue 6

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November-December 2002 Volume 9 Issue 6

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Article

Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines

  • Authors:
    • Yuzuru Higuchi
    • Jun-Ichi Asaumi
    • Jun Murakami
    • Toru Wakasa
    • Tetsuyoshi Inoue
    • Masahiro Kuroda
    • Koichi Shibuya
    • Hiroshi Shigehara
    • Shoji Kawasaki
    • Kazuhiro Fukui
    • Kanji Kishi
    • Yoshio Hiraki

  • View Affiliations

    Affiliations: Department of Oral and Maxillofacial Radiology, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan
  • Published online on: November 1, 2002     https://doi.org/10.3892/or.9.6.1233
  • Pages: 1233-1236
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Abstract

We reconstructed the recombinant p53-expressing adenovirus and examined its infections and effects in head and neck squamous cell carcinoma cell lines. Eight human head and neck squamous cell carcinoma cell lines were infected by the recombinant adenovirus harboring the lacZ gene (AxCAiLacZ) or the wild-type p53 gene (AxCAip53), and the effects were investigated. The eight cell lines were successfully infected by AxCAiLacZ at a level of more than 50%. The survival of all 8 squamous cell lines were inhibited in the range from 8 to 26.7% by only one treatment of the AxCAip53 infection. This result suggested that p53 gene therapy might become a useful tool in head and neck squamous cell carcinoma treatment.

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Copy and paste a formatted citation
Spandidos Publications style
Higuchi Y, Asaumi J, Murakami J, Wakasa T, Inoue T, Kuroda M, Shibuya K, Shigehara H, Kawasaki S, Fukui K, Fukui K, et al: Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines. Oncol Rep 9: 1233-1236, 2002.
APA
Higuchi, Y., Asaumi, J., Murakami, J., Wakasa, T., Inoue, T., Kuroda, M. ... Hiraki, Y. (2002). Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines. Oncology Reports, 9, 1233-1236. https://doi.org/10.3892/or.9.6.1233
MLA
Higuchi, Y., Asaumi, J., Murakami, J., Wakasa, T., Inoue, T., Kuroda, M., Shibuya, K., Shigehara, H., Kawasaki, S., Fukui, K., Kishi, K., Hiraki, Y."Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines". Oncology Reports 9.6 (2002): 1233-1236.
Chicago
Higuchi, Y., Asaumi, J., Murakami, J., Wakasa, T., Inoue, T., Kuroda, M., Shibuya, K., Shigehara, H., Kawasaki, S., Fukui, K., Kishi, K., Hiraki, Y."Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines". Oncology Reports 9, no. 6 (2002): 1233-1236. https://doi.org/10.3892/or.9.6.1233
Copy and paste a formatted citation
x
Spandidos Publications style
Higuchi Y, Asaumi J, Murakami J, Wakasa T, Inoue T, Kuroda M, Shibuya K, Shigehara H, Kawasaki S, Fukui K, Fukui K, et al: Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines. Oncol Rep 9: 1233-1236, 2002.
APA
Higuchi, Y., Asaumi, J., Murakami, J., Wakasa, T., Inoue, T., Kuroda, M. ... Hiraki, Y. (2002). Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines. Oncology Reports, 9, 1233-1236. https://doi.org/10.3892/or.9.6.1233
MLA
Higuchi, Y., Asaumi, J., Murakami, J., Wakasa, T., Inoue, T., Kuroda, M., Shibuya, K., Shigehara, H., Kawasaki, S., Fukui, K., Kishi, K., Hiraki, Y."Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines". Oncology Reports 9.6 (2002): 1233-1236.
Chicago
Higuchi, Y., Asaumi, J., Murakami, J., Wakasa, T., Inoue, T., Kuroda, M., Shibuya, K., Shigehara, H., Kawasaki, S., Fukui, K., Kishi, K., Hiraki, Y."Adenoviral p53 gene therapy in head and neck squamous cell carcinoma cell lines". Oncology Reports 9, no. 6 (2002): 1233-1236. https://doi.org/10.3892/or.9.6.1233
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