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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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November 2009 Volume 22 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 2009 Volume 22 Issue 5

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Article

Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer

  • Authors:
    • Yasunao Kogashiwa
    • Kohichi Yamauchi
    • Hiroshi Nagafuji
    • Takehiro Matsuda
    • Toshihito Tsubosaka
    • Tomoko Tsutsumi
    • Takehiro Karaho
    • Naoyuki Kohno

  • View Affiliations / Copyright

    Affiliations: Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo 181-8611, Japan
  • Pages: 1163-1167
    |
    Published online on: November 1, 2009
       https://doi.org/10.3892/or_00000550
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Abstract

Preservation of the larynx is the most critical factor influencing quality of life in the treatment of head and neck cancer. This clinical study focuses on laryngeal function-preserving chemoradiotherapy for locally advanced hypopharyngeal and laryngeal cancer. Thirty-two resectable cases with histologically proven squamous cell carcinoma undergoing function-preserving therapy were examined. Induction chemotherapy comprised cisplatin and 5-fluorouracil, and another cycle of chemotherapy was performed for responders. Chemoradiotherapy comprised conventional irradiation and weekly chemotherapy (nedaplatin plus docetaxel). Non-responder patients were excluded from further chemotherapy and were changed to other surgical treatment. Three patients were non-responders for induction chemotherapy, and 29 patients were treated with chemoradiotherapy. Thus, 21 out of 29 patients obtained preserved laryngeal function. Initial larynx preservation rate with these treatment strategies was 93.8%. This study provides a new concept for laryngeal function-preserving treatment that should be considered for locally advanced laryngeal and hypopharyngeal cancer.

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Copy and paste a formatted citation
Spandidos Publications style
Kogashiwa Y, Yamauchi K, Nagafuji H, Matsuda T, Tsubosaka T, Tsutsumi T, Karaho T and Kohno N: Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer. Oncol Rep 22: 1163-1167, 2009.
APA
Kogashiwa, Y., Yamauchi, K., Nagafuji, H., Matsuda, T., Tsubosaka, T., Tsutsumi, T. ... Kohno, N. (2009). Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer. Oncology Reports, 22, 1163-1167. https://doi.org/10.3892/or_00000550
MLA
Kogashiwa, Y., Yamauchi, K., Nagafuji, H., Matsuda, T., Tsubosaka, T., Tsutsumi, T., Karaho, T., Kohno, N."Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer". Oncology Reports 22.5 (2009): 1163-1167.
Chicago
Kogashiwa, Y., Yamauchi, K., Nagafuji, H., Matsuda, T., Tsubosaka, T., Tsutsumi, T., Karaho, T., Kohno, N."Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer". Oncology Reports 22, no. 5 (2009): 1163-1167. https://doi.org/10.3892/or_00000550
Copy and paste a formatted citation
x
Spandidos Publications style
Kogashiwa Y, Yamauchi K, Nagafuji H, Matsuda T, Tsubosaka T, Tsutsumi T, Karaho T and Kohno N: Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer. Oncol Rep 22: 1163-1167, 2009.
APA
Kogashiwa, Y., Yamauchi, K., Nagafuji, H., Matsuda, T., Tsubosaka, T., Tsutsumi, T. ... Kohno, N. (2009). Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer. Oncology Reports, 22, 1163-1167. https://doi.org/10.3892/or_00000550
MLA
Kogashiwa, Y., Yamauchi, K., Nagafuji, H., Matsuda, T., Tsubosaka, T., Tsutsumi, T., Karaho, T., Kohno, N."Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer". Oncology Reports 22.5 (2009): 1163-1167.
Chicago
Kogashiwa, Y., Yamauchi, K., Nagafuji, H., Matsuda, T., Tsubosaka, T., Tsutsumi, T., Karaho, T., Kohno, N."Concurrent chemoradiotherapy for organ function preservation in advanced patients with hypopharyngeal and laryngeal cancer". Oncology Reports 22, no. 5 (2009): 1163-1167. https://doi.org/10.3892/or_00000550
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