Ca2+-binding protein S100A11: A novel diagnostic marker for breast carcinoma

  • Authors:
    • Xiang-Guo Liu
    • Xiao-Ping Wang
    • Wan-Feng Li
    • Shuo Yang
    • Xin Zhou
    • Si-Jie Li
    • Xiang-Jun Li
    • Dong-Yun Hao
    • Zhi-Min Fan
  • View Affiliations

  • Published online on: May 1, 2010     https://doi.org/10.3892/or_00000764
  • Pages: 1301-1308
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Abstract

To evaluate whether S100A11 could be considered to be a novel diagnostic marker in breast carcinoma, the method of differential proteomics, Western blotting, and immunohistochemistry were used to detect the expression pattern and subcellular localization of S100A11. Statistical analyses indicated that specific up-regulated of A100A11 did not correlate with other prognostic factors such as age, tumor size, grade and stage, ER, PR, HER-2 and nodal status. Our data support that S100A11 is a novel diagnostic marker in breast carcinoma. Analysis of S100A11 expression in breast cancer may be an effective tool help in detection of early-stage breast cancer.

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May 2010
Volume 23 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Liu X, Wang X, Li W, Yang S, Zhou X, Li S, Li X, Hao D and Fan Z: Ca2+-binding protein S100A11: A novel diagnostic marker for breast carcinoma. Oncol Rep 23: 1301-1308, 2010
APA
Liu, X., Wang, X., Li, W., Yang, S., Zhou, X., Li, S. ... Fan, Z. (2010). Ca2+-binding protein S100A11: A novel diagnostic marker for breast carcinoma. Oncology Reports, 23, 1301-1308. https://doi.org/10.3892/or_00000764
MLA
Liu, X., Wang, X., Li, W., Yang, S., Zhou, X., Li, S., Li, X., Hao, D., Fan, Z."Ca2+-binding protein S100A11: A novel diagnostic marker for breast carcinoma". Oncology Reports 23.5 (2010): 1301-1308.
Chicago
Liu, X., Wang, X., Li, W., Yang, S., Zhou, X., Li, S., Li, X., Hao, D., Fan, Z."Ca2+-binding protein S100A11: A novel diagnostic marker for breast carcinoma". Oncology Reports 23, no. 5 (2010): 1301-1308. https://doi.org/10.3892/or_00000764