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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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September 2010 Volume 24 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 2010 Volume 24 Issue 3

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Article

Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma

  • Authors:
    • Kei Kubota
    • Tomoaki Yamanishi
    • Satoshi Itoh
    • Yoriko Murata
    • Kana Miyatake
    • Hiroaki Yasunami
    • Kazuo Morio
    • Norihiko Hamada
    • Akihito Nishioka
    • Yasuhiro Ogawa

  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Kochi University, Nankoku-shi, Kochi 783-8505, Japan. kubotak@kochi-u.ac.jp
  • Pages: 727-732
    |
    Published online on: September 1, 2010
       https://doi.org/10.3892/or_00000914
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Abstract

The decision to repeat transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) is based on correct evaluation of response to therapy. The purpose of this study was to investigate whether apparent diffusion coefficient (ADC), a quantitative parameter of diffusion-weighted imaging (DWI), can predict early HCC recurrence after TACE. Results obtained using this method were compared with those using iodized-oil computed tomography (CT). DWI was performed on 25 patients with 36 HCCs before and 5-7 days after TACE to calculate the ADC of HCC. Patients were also evaluated with iodized-oil CT immediately after TACE. Contrast-enhanced CT was performed 3 months after TACE to confirm early relapse of HCC lesion. After TACE, the percent change in ADC (%ADC) from before to after therapy was significantly increased in non-relapsed lesions (85.2±12.4%) compared to relapsed lesions (8.0±56.7%, p=0.0004). However, no difference in area under the curve was seen for receiver operating characteristic analysis to predict early relapse after TACE between %ADC from DWI (95% confidence interval, 0.743-1.026) and iodized-oil CT (95% confidence interval, 0.703-1.016). ADC from DWI can evaluate the efficacy of TACE for HCC as effectively as iodized-oil CT, and may help in deciding whether to repeat TACE.

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Copy and paste a formatted citation
Spandidos Publications style
Kubota K, Yamanishi T, Itoh S, Murata Y, Miyatake K, Yasunami H, Morio K, Hamada N, Nishioka A, Ogawa Y, Ogawa Y, et al: Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma . Oncol Rep 24: 727-732, 2010.
APA
Kubota, K., Yamanishi, T., Itoh, S., Murata, Y., Miyatake, K., Yasunami, H. ... Ogawa, Y. (2010). Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma . Oncology Reports, 24, 727-732. https://doi.org/10.3892/or_00000914
MLA
Kubota, K., Yamanishi, T., Itoh, S., Murata, Y., Miyatake, K., Yasunami, H., Morio, K., Hamada, N., Nishioka, A., Ogawa, Y."Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma ". Oncology Reports 24.3 (2010): 727-732.
Chicago
Kubota, K., Yamanishi, T., Itoh, S., Murata, Y., Miyatake, K., Yasunami, H., Morio, K., Hamada, N., Nishioka, A., Ogawa, Y."Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma ". Oncology Reports 24, no. 3 (2010): 727-732. https://doi.org/10.3892/or_00000914
Copy and paste a formatted citation
x
Spandidos Publications style
Kubota K, Yamanishi T, Itoh S, Murata Y, Miyatake K, Yasunami H, Morio K, Hamada N, Nishioka A, Ogawa Y, Ogawa Y, et al: Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma . Oncol Rep 24: 727-732, 2010.
APA
Kubota, K., Yamanishi, T., Itoh, S., Murata, Y., Miyatake, K., Yasunami, H. ... Ogawa, Y. (2010). Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma . Oncology Reports, 24, 727-732. https://doi.org/10.3892/or_00000914
MLA
Kubota, K., Yamanishi, T., Itoh, S., Murata, Y., Miyatake, K., Yasunami, H., Morio, K., Hamada, N., Nishioka, A., Ogawa, Y."Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma ". Oncology Reports 24.3 (2010): 727-732.
Chicago
Kubota, K., Yamanishi, T., Itoh, S., Murata, Y., Miyatake, K., Yasunami, H., Morio, K., Hamada, N., Nishioka, A., Ogawa, Y."Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma ". Oncology Reports 24, no. 3 (2010): 727-732. https://doi.org/10.3892/or_00000914
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