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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2010 Volume 24 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Evaluation of systemic external microwave hyperthermia for treatment of pleural metastasis in orthotopic lung cancer model

Tadashi Motomura, Kentaro Ueda, Shoichiro Ohtani, Erlend Hansen, Lin Ji, Koichi Ito, Kazuyuki Saito, Yoichi Sugita, Yukihiko Nosé
Pages: 591-598
Published online on: 01 September 2010

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Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion

Toshiyuki Nakayama, Hiroshi Hirakawa, Kenichiro Shibata, Kuniko Abe, Takeshi Nagayasu, Takashi Taguchi
Pages: 599-606
Published online on: 01 September 2010

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Article

Decreased expression of Annexin A10 in gastric cancer and its overexpression in tumor cell growth suppression

Jeong Kyu Kim, Pum Joon Kim, Kwang Hwa Jung, Ji Heon Noh, Jung Woo Eun, Hyun Jin Bae, Hong Jian Xie, Jin Mei Shan, Wang Ying Ping, Won Sang Park, Jung Young Lee, Suk Woo Nam
Pages: 607-612
Published online on: 01 September 2010

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Article

Utility of 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography in differential diagnosis of benign and malignant intraductal papillary-mucinous neoplasm of the pancreas

Yoshito Tomimaru, Yutaka Takeda, Mitsuaki Tatsumi, Tonsok Kim, Shogo Kobayashi, Shigeru Marubashi, Hidetoshi Eguchi, Masahiro Tanemura, Toru Kitagawa, Hiroaki Nagano, Koji Umeshita, Kenichi Wakasa, Yuichiro Doki, Masaki Mori
Pages: 613-620
Published online on: 01 September 2010

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Article

Percutaneous microwave coagulation therapy for hepatocellular carcinoma: Increased coagulation diameter using a new electrode and microwave generator

Ryosuke Inokuchi, Toshihito Seki, Kozo Ikeda, Rinako Kawamura, Toshiki Asayama, Masato Yanagawa, Hideto Umehara, Kazuichi Okazaki
Pages: 621-627
Published online on: 01 September 2010

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Article

Mechanisms of the antitumor action of the new antibiotic NC0604, a member of the bleomycin family

Weiwei Shi, Caixia Chen, Xiumin Zhang, Hongzhang Xu, Ruxian Chen, Qiyang He
Pages: 629-635
Published online on: 01 September 2010

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Article

Proteomic screening of completely resected tumors in relation to survival in patients with stage I non-small cell lung cancer

Fumihiro Oshita, Atsushi Morita, Hiroyuki Ito, Yoichi Kameda, Eiju Tsuchiya, Shigeru Asai, Yohei Miyagi
Pages: 637-645
Published online on: 01 September 2010

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Article

Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells

Hui Wang, Yan Ye, Jian-Hong Chu, Guo-Yuan Zhu, Ying-Wei Li, David W.F. Fong, Zhi-Ling Yu
Pages: 647-651
Published online on: 01 September 2010

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Article

Evaluation of ERα, PR and ERβ isoforms in neoadjuvant treated breast cancer

Martin Wurster, Alexandra Ruoff, Christoph Meisner, Harald Seeger, Ulrich Vogel, Ingolf Juhasz-Böss, Erich Solomayer, Diethelm Wallwiener, Tanja Fehm, Hans Neubauer
Pages: 653-659
Published online on: 01 September 2010

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Article

The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma

Feng-Yu Cui, Xiang-Rong Song, Zhi-Yong Li, Shuang-Zhi Li, Bo Mu, Yong-Qiu Mao, Yu-Quan Wei, Li Yang
Pages: 661-668
Published online on: 01 September 2010

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Article

Down-regulation of fractalkine inhibits the in vitro and in vivo angiogenesis of the hepatocellular carcinoma HepG2 cells

Feng Li, Zuoren Wang, Yongcun Liu, Junhui Li
Pages: 669-675
Published online on: 01 September 2010

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Article

Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3

C. R. Correa, C. M. Bertollo, C. S. Zouain, A. M. Goes
Pages: 677-685
Published online on: 01 September 2010

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Article

P504S expressing circulating prostate cells as a marker for prostate cancer

Nigel P. Murray, Gloria M. Calaf, Leonardo Badinez, Ricardo Dueñas, Orlando Badinez, Nelson Orellana, Eduardo Reyes, Cinthia Fuentealba
Pages: 687-692
Published online on: 01 September 2010

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Article

Endothelial cell-expressed Tim-3 facilitates metastasis of melanoma cells by activating the NF-κB pathway

Feng-Hua Wu, Ye Yuan, Dong Li, Zhang Lei, Chuan-Wang Song, Yan-Yan Liu, Bo Li, Bo Huang, Zuo-Hua Feng, Gui-Mei Zhang
Pages: 693-699
Published online on: 01 September 2010

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ANRIL is implicated in the regulation of nucleus and potential transcriptional target of E2F1

Kazuyuki Sato, Hiroki Nakagawa, Atsushi Tajima, Kenichi Yoshida, Ituro Inoue
Pages: 701-707
Published online on: 01 September 2010

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Small interfering RNA targeting of Recepteur d'Origine Nantais induces apoptosis via modulation of nuclear factor-κB and Bcl-2 family in gastric cancer cells

Jung Sun Park, Ji Hye Park, Soong Lee, Young Eun Joo, Young Do Jung
Pages: 709-714
Published online on: 01 September 2010

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FBXO31 is down-regulated and may function as a tumor suppressor in hepatocellular carcinoma

Hai-Li Huang, Wen-Ling Zheng, Rui Zhao, Bao Zhang, Wen-Li Ma
Pages: 715-720
Published online on: 01 September 2010

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Article

N-myc downstream-regulated gene 1/Cap43 expression promotes cell differentiation of human osteosarcoma cells

Toru Matsugaki, Michihisa Zenmyo, Koji Hiraoka, Nobuhiro Fukushima, Takanori Shoda, Setsuro Komiya, Mayumi Ono, Michihiko Kuwano, Kensei Nagata
Pages: 721-725
Published online on: 01 September 2010

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Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma

Kei Kubota, Tomoaki Yamanishi, Satoshi Itoh, Yoriko Murata, Kana Miyatake, Hiroaki Yasunami, Kazuo Morio, Norihiko Hamada, Akihito Nishioka, Yasuhiro Ogawa
Pages: 727-732
Published online on: 01 September 2010

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Promotion of hematogenous metastatic potentials in human KB carcinoma cells with overexpression of cyclooxygenase-2

Emi Segawa, Hiromitsu Kishimoto, Kazuki Takaoka, Kazuma Noguchi, Susumu Hashitani, Kazunari Sakurai, Masahiro Urade
Pages: 733-739
Published online on: 01 September 2010

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Skeletal muscle of gastric cancer patients expresses genes involved in muscle regeneration

Patrizia Pessina, Valentina Conti, Fabio Pacelli, Fausto Rosa, Giovan Battista Doglietto, Silvia Brunelli, Maurizio Bossola
Pages: 741-745
Published online on: 01 September 2010

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Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines

M. W. Roomi, J. C. Monterrey, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 747-757
Published online on: 01 September 2010

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Significant elevation of CLDN16 and HAPLN3 gene expression in human breast cancer

Shou-Jen Kuo, Su-Yu Chien, Che Lin, Szu-Erh Chan, Hsiu-Ting Tsai, Dar-Ren Chen
Pages: 759-766
Published online on: 01 September 2010

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One year survival with poorly differentiated metastatic pancreatic carcinoma following chemoembolization with gemcitabine and cisplatin

Daniel B. Brown, Carin F. Gonsalves, Charles J. Yeo, Agnes K. Witkiewicz, Brian I. Carr
Pages: 767-769
Published online on: 01 September 2010

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Article

Apoptotic activity of a new jasmonate analogue is associated with its induction of DNA damage

Jing Zhao, Saeromi Kang, Xin Zhang, Song You, Jang-Su Park, Jee H. Jung, Dong-Kyoo Kim
Pages: 771-777
Published online on: 01 September 2010

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Article

In vitro mechanism of action for the cytotoxicity elicited by the combination of epigallocatechin gallate and raloxifene in MDA-MB-231 cells

Emma C. Stuart, Reagan M. Jarvis, Rhonda J. Rosengren
Pages: 779-785
Published online on: 01 September 2010

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Article

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation

Kibeom Jang, Minsoon Kim, Hye-Sook Seo, Incheol Shin
Pages: 787-793
Published online on: 01 September 2010

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A phase II study of personalized peptide vaccination combined with gemcitabine for non-resectable pancreatic cancer patients

Hiroaki Yanagimoto, Hisanori Shiomi, Sohei Satoi, Takashi Mine, Hideyoshi Toyokawa, Tomohisa Yamamoto, Tohru Tani, Akira Yamada, A-Hon Kwon, Nobukazu Komatsu, Kyogo Itoh, Masanori Noguchi
Pages: 795-801
Published online on: 01 September 2010

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Article

Natural killer-like T CD3+/CD16+CD56+ cells in chronic lymphocytic leukemia: Intracellular cytokine expression and relationship with clinical outcome

Agnieszka Bojarska-Junak, Iwona Hus, Malgorzata Sieklucka, Ewa Wasik-Szczepanek, Tomasz Mazurkiewicz, Pawel Polak, Anna Dmoszynska, Jacek Rolinski
Pages: 803-810
Published online on: 01 September 2010

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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