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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2010 Volume 24 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Evaluation of systemic external microwave hyperthermia for treatment of pleural metastasis in orthotopic lung cancer model

Tadashi Motomura, Kentaro Ueda, Shoichiro Ohtani, Erlend Hansen, Lin Ji, Koichi Ito, Kazuyuki Saito, Yoichi Sugita, Yukihiko Nosé
Pages: 591-598
Published online on: 01 September 2010

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Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion

Toshiyuki Nakayama, Hiroshi Hirakawa, Kenichiro Shibata, Kuniko Abe, Takeshi Nagayasu, Takashi Taguchi
Pages: 599-606
Published online on: 01 September 2010

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Decreased expression of Annexin A10 in gastric cancer and its overexpression in tumor cell growth suppression

Jeong Kyu Kim, Pum Joon Kim, Kwang Hwa Jung, Ji Heon Noh, Jung Woo Eun, Hyun Jin Bae, Hong Jian Xie, Jin Mei Shan, Wang Ying Ping, Won Sang Park, Jung Young Lee, Suk Woo Nam
Pages: 607-612
Published online on: 01 September 2010

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Utility of 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography in differential diagnosis of benign and malignant intraductal papillary-mucinous neoplasm of the pancreas

Yoshito Tomimaru, Yutaka Takeda, Mitsuaki Tatsumi, Tonsok Kim, Shogo Kobayashi, Shigeru Marubashi, Hidetoshi Eguchi, Masahiro Tanemura, Toru Kitagawa, Hiroaki Nagano, Koji Umeshita, Kenichi Wakasa, Yuichiro Doki, Masaki Mori
Pages: 613-620
Published online on: 01 September 2010

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Article

Percutaneous microwave coagulation therapy for hepatocellular carcinoma: Increased coagulation diameter using a new electrode and microwave generator

Ryosuke Inokuchi, Toshihito Seki, Kozo Ikeda, Rinako Kawamura, Toshiki Asayama, Masato Yanagawa, Hideto Umehara, Kazuichi Okazaki
Pages: 621-627
Published online on: 01 September 2010

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Article

Mechanisms of the antitumor action of the new antibiotic NC0604, a member of the bleomycin family

Weiwei Shi, Caixia Chen, Xiumin Zhang, Hongzhang Xu, Ruxian Chen, Qiyang He
Pages: 629-635
Published online on: 01 September 2010

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Proteomic screening of completely resected tumors in relation to survival in patients with stage I non-small cell lung cancer

Fumihiro Oshita, Atsushi Morita, Hiroyuki Ito, Yoichi Kameda, Eiju Tsuchiya, Shigeru Asai, Yohei Miyagi
Pages: 637-645
Published online on: 01 September 2010

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Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells

Hui Wang, Yan Ye, Jian-Hong Chu, Guo-Yuan Zhu, Ying-Wei Li, David W.F. Fong, Zhi-Ling Yu
Pages: 647-651
Published online on: 01 September 2010

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Evaluation of ERα, PR and ERβ isoforms in neoadjuvant treated breast cancer

Martin Wurster, Alexandra Ruoff, Christoph Meisner, Harald Seeger, Ulrich Vogel, Ingolf Juhasz-Böss, Erich Solomayer, Diethelm Wallwiener, Tanja Fehm, Hans Neubauer
Pages: 653-659
Published online on: 01 September 2010

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The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma

Feng-Yu Cui, Xiang-Rong Song, Zhi-Yong Li, Shuang-Zhi Li, Bo Mu, Yong-Qiu Mao, Yu-Quan Wei, Li Yang
Pages: 661-668
Published online on: 01 September 2010

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Down-regulation of fractalkine inhibits the in vitro and in vivo angiogenesis of the hepatocellular carcinoma HepG2 cells

Feng Li, Zuoren Wang, Yongcun Liu, Junhui Li
Pages: 669-675
Published online on: 01 September 2010

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Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3

C. R. Correa, C. M. Bertollo, C. S. Zouain, A. M. Goes
Pages: 677-685
Published online on: 01 September 2010

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Article

P504S expressing circulating prostate cells as a marker for prostate cancer

Nigel P. Murray, Gloria M. Calaf, Leonardo Badinez, Ricardo Dueñas, Orlando Badinez, Nelson Orellana, Eduardo Reyes, Cinthia Fuentealba
Pages: 687-692
Published online on: 01 September 2010

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Endothelial cell-expressed Tim-3 facilitates metastasis of melanoma cells by activating the NF-κB pathway

Feng-Hua Wu, Ye Yuan, Dong Li, Zhang Lei, Chuan-Wang Song, Yan-Yan Liu, Bo Li, Bo Huang, Zuo-Hua Feng, Gui-Mei Zhang
Pages: 693-699
Published online on: 01 September 2010

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ANRIL is implicated in the regulation of nucleus and potential transcriptional target of E2F1

Kazuyuki Sato, Hiroki Nakagawa, Atsushi Tajima, Kenichi Yoshida, Ituro Inoue
Pages: 701-707
Published online on: 01 September 2010

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Small interfering RNA targeting of Recepteur d'Origine Nantais induces apoptosis via modulation of nuclear factor-κB and Bcl-2 family in gastric cancer cells

Jung Sun Park, Ji Hye Park, Soong Lee, Young Eun Joo, Young Do Jung
Pages: 709-714
Published online on: 01 September 2010

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FBXO31 is down-regulated and may function as a tumor suppressor in hepatocellular carcinoma

Hai-Li Huang, Wen-Ling Zheng, Rui Zhao, Bao Zhang, Wen-Li Ma
Pages: 715-720
Published online on: 01 September 2010

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N-myc downstream-regulated gene 1/Cap43 expression promotes cell differentiation of human osteosarcoma cells

Toru Matsugaki, Michihisa Zenmyo, Koji Hiraoka, Nobuhiro Fukushima, Takanori Shoda, Setsuro Komiya, Mayumi Ono, Michihiko Kuwano, Kensei Nagata
Pages: 721-725
Published online on: 01 September 2010

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Role of diffusion-weighted imaging in evaluating therapeutic efficacy after transcatheter arterial chemoembolization for hepatocellular carcinoma

Kei Kubota, Tomoaki Yamanishi, Satoshi Itoh, Yoriko Murata, Kana Miyatake, Hiroaki Yasunami, Kazuo Morio, Norihiko Hamada, Akihito Nishioka, Yasuhiro Ogawa
Pages: 727-732
Published online on: 01 September 2010

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Promotion of hematogenous metastatic potentials in human KB carcinoma cells with overexpression of cyclooxygenase-2

Emi Segawa, Hiromitsu Kishimoto, Kazuki Takaoka, Kazuma Noguchi, Susumu Hashitani, Kazunari Sakurai, Masahiro Urade
Pages: 733-739
Published online on: 01 September 2010

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Skeletal muscle of gastric cancer patients expresses genes involved in muscle regeneration

Patrizia Pessina, Valentina Conti, Fabio Pacelli, Fausto Rosa, Giovan Battista Doglietto, Silvia Brunelli, Maurizio Bossola
Pages: 741-745
Published online on: 01 September 2010

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Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines

M. W. Roomi, J. C. Monterrey, T. Kalinovsky, M. Rath, A. Niedzwiecki
Pages: 747-757
Published online on: 01 September 2010

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Significant elevation of CLDN16 and HAPLN3 gene expression in human breast cancer

Shou-Jen Kuo, Su-Yu Chien, Che Lin, Szu-Erh Chan, Hsiu-Ting Tsai, Dar-Ren Chen
Pages: 759-766
Published online on: 01 September 2010

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One year survival with poorly differentiated metastatic pancreatic carcinoma following chemoembolization with gemcitabine and cisplatin

Daniel B. Brown, Carin F. Gonsalves, Charles J. Yeo, Agnes K. Witkiewicz, Brian I. Carr
Pages: 767-769
Published online on: 01 September 2010

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Apoptotic activity of a new jasmonate analogue is associated with its induction of DNA damage

Jing Zhao, Saeromi Kang, Xin Zhang, Song You, Jang-Su Park, Jee H. Jung, Dong-Kyoo Kim
Pages: 771-777
Published online on: 01 September 2010

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In vitro mechanism of action for the cytotoxicity elicited by the combination of epigallocatechin gallate and raloxifene in MDA-MB-231 cells

Emma C. Stuart, Reagan M. Jarvis, Rhonda J. Rosengren
Pages: 779-785
Published online on: 01 September 2010

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Article

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation

Kibeom Jang, Minsoon Kim, Hye-Sook Seo, Incheol Shin
Pages: 787-793
Published online on: 01 September 2010

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A phase II study of personalized peptide vaccination combined with gemcitabine for non-resectable pancreatic cancer patients

Hiroaki Yanagimoto, Hisanori Shiomi, Sohei Satoi, Takashi Mine, Hideyoshi Toyokawa, Tomohisa Yamamoto, Tohru Tani, Akira Yamada, A-Hon Kwon, Nobukazu Komatsu, Kyogo Itoh, Masanori Noguchi
Pages: 795-801
Published online on: 01 September 2010

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Natural killer-like T CD3+/CD16+CD56+ cells in chronic lymphocytic leukemia: Intracellular cytokine expression and relationship with clinical outcome

Agnieszka Bojarska-Junak, Iwona Hus, Malgorzata Sieklucka, Ewa Wasik-Szczepanek, Tomasz Mazurkiewicz, Pawel Polak, Anna Dmoszynska, Jacek Rolinski
Pages: 803-810
Published online on: 01 September 2010

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Number: 183
Published online on: 31 August 2026

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