Open Access

Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4

  • Authors:
    • Shohei Asada
    • Akitoshi Douhara
    • Hirotsugu Ueno
    • Koji Murata
    • Koji Yanase
    • Hitoshi Yoshiji
  • View Affiliations

  • Published online on: January 30, 2020     https://doi.org/10.3892/wasj.2020.36
  • Pages: 28-34
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Abstract

The aim of the present study was to clarify the efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) for elderly patients with a performance status (PS) of 3‑4, which is the highest risk group. The records of patients aged over 75 years of age, who underwent ERCP at Saiseikai Chuwa Hospital from April, 2017 to April, 2018, were retrospectively analyzed. These patients were divided into the PS 0‑2 group and PS 3‑4 group. For both groups, clinical characteristics, such as age, sex, PS, the prevalence rate of moderate or severe cholangitis, Charlson comorbidity index (CCI), technical success rate, adverse events and fatal cases within 30 days following ERCP were analyzed. The results revealed that in total, 94 patients (158 procedures) aged over 75 years underwent ERCPs; 73 patients (116 procedures) were in the PS 0‑2 group, and 21 patients (42 procedures) were in the PS 3‑4 group. The average age did not differ significantly between the groups. The prevalence rates of moderate or severe cholangitis and CCI were higher in the PS 3‑4 group. The technical success rate was high in both groups. Although the rate of adverse events did not differ between the 2 groups, 2 fatal cases occurred during the 30 days following ERCP in the PS 3‑4 group. In each case, anorexia and an influenza infection led to a fatal outcome. Overall, this study demonstrates that ERCP for elderly patients with a PS of 3‑4 is effective and safe. However, attention should be paid to ERCP in patients with a PS of 3‑4, as it may result in a fatal outcome caused by incidents unrelated to the ERCP procedure.

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January 2020
Volume 2 Issue 1

Print ISSN: 2632-2900
Online ISSN:2632-2919

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APA
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., & Yoshiji, H. (2020). Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4. World Academy of Sciences Journal, 2, 28-34. https://doi.org/10.3892/wasj.2020.36
MLA
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., Yoshiji, H."Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4". World Academy of Sciences Journal 2.1 (2020): 28-34.
Chicago
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., Yoshiji, H."Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4". World Academy of Sciences Journal 2, no. 1 (2020): 28-34. https://doi.org/10.3892/wasj.2020.36