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Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4

  • Authors:
    • Shohei Asada
    • Akitoshi Douhara
    • Hirotsugu Ueno
    • Koji Murata
    • Koji Yanase
    • Hitoshi Yoshiji
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, Saiseikai Chuwa Hospital, Sakurai, Nara 633‑0054, Japan, Third Department of Internal Medicine, Nara Medical University, Kashihara, Nara 634‑8522, Japan
    Copyright: © Asada et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 28-34
    |
    Published online on: January 30, 2020
       https://doi.org/10.3892/wasj.2020.36
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Abstract

The aim of the present study was to clarify the efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) for elderly patients with a performance status (PS) of 3‑4, which is the highest risk group. The records of patients aged over 75 years of age, who underwent ERCP at Saiseikai Chuwa Hospital from April, 2017 to April, 2018, were retrospectively analyzed. These patients were divided into the PS 0‑2 group and PS 3‑4 group. For both groups, clinical characteristics, such as age, sex, PS, the prevalence rate of moderate or severe cholangitis, Charlson comorbidity index (CCI), technical success rate, adverse events and fatal cases within 30 days following ERCP were analyzed. The results revealed that in total, 94 patients (158 procedures) aged over 75 years underwent ERCPs; 73 patients (116 procedures) were in the PS 0‑2 group, and 21 patients (42 procedures) were in the PS 3‑4 group. The average age did not differ significantly between the groups. The prevalence rates of moderate or severe cholangitis and CCI were higher in the PS 3‑4 group. The technical success rate was high in both groups. Although the rate of adverse events did not differ between the 2 groups, 2 fatal cases occurred during the 30 days following ERCP in the PS 3‑4 group. In each case, anorexia and an influenza infection led to a fatal outcome. Overall, this study demonstrates that ERCP for elderly patients with a PS of 3‑4 is effective and safe. However, attention should be paid to ERCP in patients with a PS of 3‑4, as it may result in a fatal outcome caused by incidents unrelated to the ERCP procedure.
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1 

Ukkonen M, Siiki A, Antila A, Tyrväinen T, Sand J and Laukkarinen J: Safety and efficacy of acute endoscopic retrograde cholangiopancreatography in the elderly. Dig Dis Sci. 61:3302–3308. 2016.PubMed/NCBI View Article : Google Scholar

2 

Galeazzi M, Mazzola P, Valcarcel B, Bellelli G, Dinelli M, Pasinetti GM and Annoni G: Endoscopic retrograde cholangiopancreatography in the elderly: Results of a retrospective study and a geriatricians' point of view. BMC Gastroenterol. 18(38)2018.PubMed/NCBI View Article : Google Scholar

3 

Tohda G, Ohtani M and Dochin M: Efficacy and safety of emergency endoscopic retrograde cholangiopancreatography for acute cholangitis in the elderly. World J Gastroenterol. 22:8382–8388. 2016.PubMed/NCBI View Article : Google Scholar

4 

Yun DY, Han J, Oh JS, Park KW, Shin IH and Kim HG: Is endoscopic retrograde cholangiopancreatography safe in patients 90 years of age and older? Gut Liver. 8:552–556. 2014.PubMed/NCBI View Article : Google Scholar

5 

Behlül B, Ayfer S, Sezgin V, Altay K, Mustafa C, Cem C, Bilge O, Fatih A, Emrah A, Zafer B, et al: Safety of endoscopic retrograde cholangiopancreatography in patients 80 years of age and older. Prz Gastroenterol. 9:227–231. 2014.PubMed/NCBI View Article : Google Scholar

6 

Mohammad Alizadeh AH, Afzali ES, Shahnazi A, Sanati A, Mirsattari D and Zali MR: Utility and safety of ERCP in the elderly: A comparative study in Iran. Diagn Ther Endosc. 2012(439320)2012.PubMed/NCBI View Article : Google Scholar

7 

Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET and Carbone PP: Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 5:649–655. 1982.PubMed/NCBI

8 

Takada T, Strasberg SM, Solomkin JS, Pitt HA, Gomi H, Yoshida M, Mayumi T, Miura F, Gouma DJ, Garden OJ, et al: TG13: Updated Tokyo guidelines for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci. 20:1–7. 2013.PubMed/NCBI View Article : Google Scholar

9 

Charlson ME, Pompei P, Ales KL and MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis. 40:373–383. 1987.PubMed/NCBI View Article : Google Scholar

10 

Miura F, Takada T, Strasberg SM, Solomkin JS, Pitt HA, Gouma DJ, Garden OJ, Büchler MW, Yoshida M, Mayumi T, et al: TG13 flowchart for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci. 20:47–54. 2013.PubMed/NCBI View Article : Google Scholar

11 

Tanisaka Y, Ryozawa S, Mizuide M, Kobayashi M, Fujita A, Minami K, Kobatake T, Omiya K, Iwano H and Araki R: Usefulness of the ‘newly designed’ short-type single-balloon enteroscope for ERCP in patients with Roux-en-Y gastrectomy: A pilot study. Endosc Int Open. 6:E1417–E1422. 2018.PubMed/NCBI View Article : Google Scholar

12 

Maple JT, Keswani RN, Hovis RM, Saddedin EZ, Jonnalagadda S, Azar RR, Hagen C, Thompson DM, Waldbaum L and Edmundowicz SA: Carbon dioxide insufflation during ERCP for reduction of postprocedure pain: A randomized, double-blind, controlled trial. Gastrointest Endosc. 70:278–283. 2009.PubMed/NCBI View Article : Google Scholar

13 

Nakamura K, Yamaguchi Y, Hasue T, Higa K, Tauchi M, Toki M, Sugiyama M and Takahashi S: The usefulness and safety of carbon dioxide insufflation during endoscopic retrograde cholangiopancreatography in elderly patients: A prospective, double-blind, randomized, controlled trial. Hepatogastroenterology. 61:2191–2195. 2014.PubMed/NCBI

14 

Adler DG, Baron TH, Davila RE, Egan J, Hirota WK, Leighton JA, Qureshi W, Rajan E, Zuckerman MJ, Fanelli R, et al: ASGE guideline: The role of ERCP in diseases of the biliary tract and the pancreas. Gastrointest Endosc. 62:1–8. 2005.PubMed/NCBI View Article : Google Scholar

15 

Mallery JS, Baron TH, Dominitz JA, Goldstein JL, Hirota WK, Jacobson BC, Leighton JA, Raddawi HM, Varg JJ II, Waring JP, et al: Complications of ERCP. Gastrointest Endosc. 57:633–638. 2003.PubMed/NCBI View Article : Google Scholar

16 

Ellis G, Whitehead MA, O'Neill D, Langhorne P and Robinson D: Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev. 2011(CD006211)2011.PubMed/NCBI View Article : Google Scholar

17 

Park TY, Choi JS, Oh HC, Kim JW, Do JH and Jung YH: Assessment of safety of non-anesthesiologist-assisted endoscopic retrograde cholangiopancreatography based on performance status in elderly patients. J Gastroenterol Hepatol. 29:1943–1948. 2014.PubMed/NCBI View Article : Google Scholar

18 

Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Califf RM, Cobb FR and Pryor DB: A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol. 64:651–654. 1989.PubMed/NCBI View Article : Google Scholar

19 

Takahashi K, Nihei T, Aoki Y, Nakagawa M, Konno N, Munakata A, Okawara K and Kashimura H: Efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography in patients with native papillae with a performance status score of 3 or 4: A single-center retrospective study. J Rural Med. 14:226–230. 2019.PubMed/NCBI View Article : Google Scholar

20 

Endo I, Takada T, Hwang TL, Akazawa K, Mori R, Miura F, Yokoe M, Itoi T, Gomi H, Chen MF, et al: Optimal treatment strategy for acute cholecystitis based on predictive factors: Japan-Taiwan multicenter cohort study. J Hepatobiliary Pancreat Sci. 24:346–361. 2017.PubMed/NCBI View Article : Google Scholar

21 

Ando K, Doi T, Moody SY, Ohkuni Y, Sato S and Kaneko N: The effect of comorbidity on the prognosis of acute lung injury and acute respiratory distress syndrome. Intern Med. 51:1835–1840. 2012.PubMed/NCBI View Article : Google Scholar

22 

Naito Y, Sasaki H, Takamatsu Y, Kiyomi F and Tamura K: Retrospective analysis of treatment outcomes and geriatric assessment in elderly malignant lymphoma patients. J Clin Exp Hematop. 56:43–49. 2016.PubMed/NCBI View Article : Google Scholar

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Spandidos Publications style
Asada S, Douhara A, Ueno H, Murata K, Yanase K and Yoshiji H: Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4. World Acad Sci J 2: 28-34, 2020.
APA
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., & Yoshiji, H. (2020). Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4. World Academy of Sciences Journal, 2, 28-34. https://doi.org/10.3892/wasj.2020.36
MLA
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., Yoshiji, H."Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4". World Academy of Sciences Journal 2.1 (2020): 28-34.
Chicago
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., Yoshiji, H."Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4". World Academy of Sciences Journal 2, no. 1 (2020): 28-34. https://doi.org/10.3892/wasj.2020.36
Copy and paste a formatted citation
x
Spandidos Publications style
Asada S, Douhara A, Ueno H, Murata K, Yanase K and Yoshiji H: Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4. World Acad Sci J 2: 28-34, 2020.
APA
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., & Yoshiji, H. (2020). Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4. World Academy of Sciences Journal, 2, 28-34. https://doi.org/10.3892/wasj.2020.36
MLA
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., Yoshiji, H."Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4". World Academy of Sciences Journal 2.1 (2020): 28-34.
Chicago
Asada, S., Douhara, A., Ueno, H., Murata, K., Yanase, K., Yoshiji, H."Efficacy and safety of ERCP in elderly patients with an ECOG performance status of 3‑4". World Academy of Sciences Journal 2, no. 1 (2020): 28-34. https://doi.org/10.3892/wasj.2020.36
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