Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
World Academy of Sciences Journal
Join Editorial Board Propose a Special Issue
Print ISSN: 2632-2900 Online ISSN: 2632-2919
Journal Cover
March-April 2020 Volume 2 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-April 2020 Volume 2 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice

  • Authors:
    • Ramin Rezaee
    • Saeedeh Jangjoo
    • Sarvenaz Ekhtiary
    • Mohammad Amir Anani
    • Aristidis Tsatsakis
    • Demetrios A. Spandidos
    • Charitini Nepka
    • Mahmoud Hashemzaei
  • View Affiliations / Copyright

    Affiliations: Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, 913753316 Mashhad, Iran, Students Research Committee, School of Pharmacy, Zabol University of Medical Sciences, 9861615881 Zabol, Iran, Laboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Greece, Department of Virology, Medical School, University of Crete, 71003 Heraklion, Greece, Department of Pathology and Cytology, University Hospital of Larissa, 41110 Larissa, Greece
    Copyright: © Rezaee et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 77-82
    |
    Published online on: February 17, 2020
       https://doi.org/10.3892/wasj.2020.38
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Seeking opioids, even after a prolonged withdrawal period, is a main concern of opioid withdrawal. Resveratrol (RES) has been shown to exert inhibitory effects on glutamate release from cerebrocortical nerve terminals via N‑methyl‑D‑aspartate (NMDA) antagonistic effects. In this study, the effects of RES on the acquisition and reinstatement of morphine were examined in a mouse model using the morphine‑induced conditioned place preference (CPP) paradigm. In the first step, namely the acquisition phase, morphine was administered to mice for 4 consecutive days (daily 40 mg/kg, i.p. injection) and the mice were trained in a CPP chamber. In the second step, namely extinction and reinstatement, the animals underwent the same CPP training followed by extinction training on day 16 and reinstatement was investigated by CPP following the administration of a ‘reminding’ dose of morphine (10 mg/kg). Finally, the effects of RES (25, 50 and 75 mg/kg) on the acquisition and reinstatement induced by morphine were examined in a CPP test. Based on our data, RES (25, 50 and 75 mg/kg) reduced morphine tendency. In the second step of the experiment, after day 16 (following the ‘reminder’ dose of morphine at 10 mg/kg), the tendency of the animals for the white, drug‑paired compartment of the CPP chamber significantly decreased following treatment with RES at 50 and 75 mg/kg (but not at 25 mg/kg). On the whole, the findings of this study demonstrate that RES decreases the acquisition and reinstatement of morphine‑induced CPP in mice.
View Figures

Figure 1

Figure 2

View References

1 

Kest B, McLemore G, Kao B and Inturrisi CE: The competitive α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist LY293558 attenuates and reverses analgesic tolerance to morphine but not to delta or kappa opioids. J Pharmacol Exp Ther. 283:1249–1255. 1997.PubMed/NCBI

2 

Mayer DJ, Mao J, Holt J and Price DD: Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions. Proc Natl Acad Sci USA. 96:7731–7736. 1999.PubMed/NCBI View Article : Google Scholar

3 

Tsatsakis A, Docea AO, Calina D, Tsarouhas K, Zamfira LM, Mitrut R, Sharifi-Rad J, Kovatsi L, Siokas V, Dardiotis E, et al: A Mechanistic and Pathophysiological Approach for Stroke Associated with Drugs of Abuse. J Clin Med. 8(1295)2019.PubMed/NCBI View Article : Google Scholar

4 

Kratzer U and Schmidt WJ: The anti-craving drug acamprosate inhibits the conditioned place aversion induced by naloxone-precipitated morphine withdrawal in rats. Neurosci Lett. 252:53–56. 1998.PubMed/NCBI View Article : Google Scholar

5 

Theberge FR, Li X, Kambhampati S, Pickens CL, St Laurent R, Bossert JM, Baumann MH, Hutchinson MR, Rice KC, Watkins LR, et al: Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving. Biol Psychiatry. 73:729–737. 2013.PubMed/NCBI View Article : Google Scholar

6 

Dhawan K, Kumar S and Sharma A: Reversal of Morphine Tolerance and Dependence by Passiflora incarnata - A Traditional Medicine to Combat Morphine Addiction. Pharm Biol. 40:576–580. 2002.

7 

Tabatabai SM, Dashti S, Doosti F and Hosseinzadeh H: Phytotherapy of opioid dependence and withdrawal syndrome: A review. Phytother Res. 28:811–830. 2014.PubMed/NCBI View Article : Google Scholar

8 

Ribeiro Do Couto B, Aguilar MA, Manzanedo C, Rodríguez-Arias M and Miñarro J: Effects of NMDA receptor antagonists (MK-801 and memantine) on the acquisition of morphine-induced conditioned place preference in mice. Prog Neuropsychopharmacol Biol Psychiatry. 28:1035–1043. 2004.PubMed/NCBI View Article : Google Scholar

9 

Guo SJ, Cui Y, Huang ZZ, Liu H, Zhang XQ, Jiang JX and Xin WJ: Orexin A-mediated AKT signaling in the dentate gyrus contributes to the acquisition, expression and reinstatement of morphine-induced conditioned place preference. Addict Biol. 21:547–559. 2016.PubMed/NCBI View Article : Google Scholar

10 

Al-Harthi SE, Alarabi OM, Ramadan WS, Alaama MN, Al-Kreathy HM, Damanhouri ZA, Khan LM and Osman AM: Amelioration of doxorubicin induced cardiotoxicity by resveratrol. Mol Med Rep. 10:1455–1460. 2014.PubMed/NCBI View Article : Google Scholar

11 

Hamza RZ and El-Shenawy NS: Anti-inflammatory and antioxidant role of resveratrol on nicotine-induced lung changes in male rats. Toxicol Rep. 4:399–407. 2017.PubMed/NCBI View Article : Google Scholar

12 

Theodotou M, Fokianos K, Moniatis D, Kadlenic R, Chrysikou A, Aristotelous A, Mouzouridou A, Diakides J and Stavrou E: Effect of resveratrol on non-alcoholic fatty liver disease. Exp Ther Med. 18:559–565. 2019.PubMed/NCBI View Article : Google Scholar

13 

Goutzourelas N, Stagos D, Spanidis Y, Liosi M, Apostolou A, Priftis A, Haroutounian S, Spandidos DA, Tsatsakis AM and Kouretas D: Polyphenolic composition of grape stem extracts affects antioxidant activity in endothelial and muscle cells. Mol Med Rep. 12:5846–5856. 2015.PubMed/NCBI View Article : Google Scholar

14 

Hashemzaei M, Barani AK, Iranshahi M, Rezaee R, Tsarouhas K, Tsatsakis AM, Wilks MF and Tabrizian K: Effects of resveratrol on carbon monoxide-induced cardiotoxicity in rats. Environ Toxicol Pharmacol. 46:110–115. 2016.PubMed/NCBI View Article : Google Scholar

15 

Hashemzaei M, Karami SP, Delaramifar A, Sheidary A, Tabrizian K, Rezaee R, Shahsavand S, Arsene AL, Tsatsakis AM and Taghdisi SM: Anticancer effects of co-administration of daunorubicin and resveratrol in MOLT-4, U266 B1 and RAJI cell lines. Farmacia. 64:36–42. 2016.

16 

Labinskyy N, Csiszar A, Veress G, Stef G, Pacher P, Oroszi G, Wu J and Ungvari Z: Vascular dysfunction in aging: Potential effects of resveratrol, an anti-inflammatory phytoestrogen. Curr Med Chem. 13:989–996. 2006.PubMed/NCBI View Article : Google Scholar

17 

Russo GL: Ins and outs of dietary phytochemicals in cancer chemoprevention. Biochem Pharmacol. 74:533–544. 2007.PubMed/NCBI View Article : Google Scholar

18 

Tabrizian K, Musavi SS, Rigi M, Hosseindadi F, Kordi S, Shamshirgaran F, Bazi A, Shahraki J, Rezaee R and Hashemzaei M: Behavioral and molecular effects of intrahippocampal infusion of auraptene, resveratrol, and curcumin on H-89-induced deficits on spatial memory acquisition and retention in Morris water maze. Hum Exp Toxicol. 38:775–784. 2019.PubMed/NCBI View Article : Google Scholar

19 

Tabrizian K, Shahraki J, Bazzi M, Rezaee R, Jahantigh H and Hashemzaei M: Neuro-Protective Effects of Resveratrol on Carbon Monoxide-Induced Toxicity in Male Rats. Phytother Res. 31:1310–1315. 2017.PubMed/NCBI View Article : Google Scholar

20 

Zhao YN, Li WF, Li F, Zhang Z, Dai YD, Xu AL, Qi C, Gao JM and Gao J: Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway. Biochem Biophys Res Commun. 435:597–602. 2013.PubMed/NCBI View Article : Google Scholar

21 

Ghazanfarpour M, Najafi MN, Roozbeh N, Mashhadi ME, Keramat-Roudi A, Mégarbane B, Tsatsakis A, Moghaddam MMM and Rezaee R: Therapeutic approaches for neonatal abstinence syndrome: A systematic review of randomized clinical trials. Daru. 27:423–431. 2019.PubMed/NCBI View Article : Google Scholar

22 

Gentilli M, Mazoit JX, Bouaziz H, Fletcher D, Casper RF, Benhamou D and Savouret JF: Resveratrol decreases hyperalgesia induced by carrageenan in the rat hind paw. Life Sci. 68:1317–1321. 2001.PubMed/NCBI View Article : Google Scholar

23 

Tsai RY, Chou KY, Shen CH, Chien CC, Tsai WY, Huang YN, Tao PL, Lin YS and Wong CS: Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats. Anesth Analg. 115:944–952. 2012.PubMed/NCBI View Article : Google Scholar

24 

Shen CH, Tsai RY, Tai YH, Lin SL, Chien CC and Wong CS: Intrathecal etanercept partially restores morphine's antinociception in morphine-tolerant rats via attenuation of the glutamatergic transmission. Anesth Analg. 113:184–190. 2011.PubMed/NCBI View Article : Google Scholar

25 

Schmatz R, Mazzanti CM, Spanevello R, Stefanello N, Gutierres J, Corrêa M, da Rosa MM, Rubin MA, Chitolina Schetinger MR and Morsch VM: Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats. Eur J Pharmacol. 610:42–48. 2009.PubMed/NCBI View Article : Google Scholar

26 

Marambaud P, Zhao H and Davies P: Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides. J Biol Chem. 280:37377–37382. 2005.PubMed/NCBI View Article : Google Scholar

27 

MacCarrone M, Lorenzon T, Guerrieri P and Agrò AF: Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity. Eur J Biochem. 265:27–34. 1999.PubMed/NCBI View Article : Google Scholar

28 

Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H, Jang M, Pezzuto JM and Dannenberg AJ: Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem. 273:21875–21882. 1998.PubMed/NCBI View Article : Google Scholar

29 

Subbaramaiah K, Michaluart P, Chung WJ, Tanabe T, Telang N and Dannenberg AJ: Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Ann N Y Acad Sci. 889:214–223. 1999.PubMed/NCBI View Article : Google Scholar

30 

Pérez-Severiano F, Bermúdez-Ocaña DY, López-Sánchez P, Ríos C and Granados-Soto V: Spinal nerve ligation reduces nitric oxide synthase activity and expression: Effect of resveratrol. Pharmacol Biochem Behav. 90:742–747. 2008.PubMed/NCBI View Article : Google Scholar

31 

Imenshahidi M, Qaredashi R, Hashemzaei M and Hosseinzadeh H: Inhibitory Effect of Berberis vulgaris Aqueous Extract on Acquisition and Reinstatement Effects of Morphine in Conditioned Place Preferences (CPP) in Mice. Jundishapur J Nat Pharm Prod. 9(e16145)2014.PubMed/NCBI View Article : Google Scholar

32 

Qaredashi R, Hosseinzadeh H and Hashemzaei M: Inhibitory effect of Berberis vulgaris aqueous extract on acquisition and reinstatement effects of morphine in conditioned place preferences (CPP) in mice. Res Pharm Sci. 7(S839)2012.

33 

Gao ZB, Chen XQ and Hu GY: Inhibition of excitatory synaptic transmission by trans-resveratrol in rat hippocampus. Brain Res. 1111:41–47. 2006.PubMed/NCBI View Article : Google Scholar

34 

Chang Y and Wang SJ: Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by resveratrol. Neurochem Int. 54:135–141. 2009.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
Copy and paste a formatted citation
Spandidos Publications style
Rezaee R, Jangjoo S, Ekhtiary S, Anani MA, Tsatsakis A, Spandidos DA, Nepka C and Hashemzaei M: Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice. World Acad Sci J 2: 77-82, 2020.
APA
Rezaee, R., Jangjoo, S., Ekhtiary, S., Anani, M.A., Tsatsakis, A., Spandidos, D.A. ... Hashemzaei, M. (2020). Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice. World Academy of Sciences Journal, 2, 77-82. https://doi.org/10.3892/wasj.2020.38
MLA
Rezaee, R., Jangjoo, S., Ekhtiary, S., Anani, M. A., Tsatsakis, A., Spandidos, D. A., Nepka, C., Hashemzaei, M."Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice". World Academy of Sciences Journal 2.2 (2020): 77-82.
Chicago
Rezaee, R., Jangjoo, S., Ekhtiary, S., Anani, M. A., Tsatsakis, A., Spandidos, D. A., Nepka, C., Hashemzaei, M."Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice". World Academy of Sciences Journal 2, no. 2 (2020): 77-82. https://doi.org/10.3892/wasj.2020.38
Copy and paste a formatted citation
x
Spandidos Publications style
Rezaee R, Jangjoo S, Ekhtiary S, Anani MA, Tsatsakis A, Spandidos DA, Nepka C and Hashemzaei M: Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice. World Acad Sci J 2: 77-82, 2020.
APA
Rezaee, R., Jangjoo, S., Ekhtiary, S., Anani, M.A., Tsatsakis, A., Spandidos, D.A. ... Hashemzaei, M. (2020). Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice. World Academy of Sciences Journal, 2, 77-82. https://doi.org/10.3892/wasj.2020.38
MLA
Rezaee, R., Jangjoo, S., Ekhtiary, S., Anani, M. A., Tsatsakis, A., Spandidos, D. A., Nepka, C., Hashemzaei, M."Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice". World Academy of Sciences Journal 2.2 (2020): 77-82.
Chicago
Rezaee, R., Jangjoo, S., Ekhtiary, S., Anani, M. A., Tsatsakis, A., Spandidos, D. A., Nepka, C., Hashemzaei, M."Effects of resveratrol on the acquisition and reinstatement of morphine‑induced conditioned place preference in mice". World Academy of Sciences Journal 2, no. 2 (2020): 77-82. https://doi.org/10.3892/wasj.2020.38
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team