Open Access

Long‑term outcomes in patients with benign central airway stenosis or obstruction following stenting

  • Authors:
    • Akira Iyoda
    • Yoko Azuma
    • Atsushi Sano
    • Takashi Sakai
    • Satoshi Koezuka
    • Hajime  Otsuka
    • Kazutoshi Isobe
    • Susumu Sakamoto
    • Yoshinobu Hata
    • Keigo Takagi
  • View Affiliations

  • Published online on: July 17, 2020     https://doi.org/10.3892/wasj.2020.61
  • Article Number: 20
  • Copyright: © Iyoda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Although an airway stent is used for central airway stenosis or obstruction due to benign diseases, the long‑term outcomes of stenting are unknown. The aim of the present study was to identify the clinical features and outcomes of patients with airway stenosis or obstruction due to benign disease who underwent stenting procedures. For this purpose, clinical data from 136 patients with stents for central airway stenosis or obstruction who underwent treatment at Toho University Omori Medical Center from 1998 to 2018 were retrospectively analyzed. The clinical features, outcomes and complications associated with stenting were evaluated. The clinical features of patients with stents for benign central airway stenosis or obstruction were compared to those of patients with stents for malignant disease. Of the 136 patients with stents, 19 patients had benign disease and 117 had malignant disease. The difference between complications in patients with benign disease compared with those with malignant disease was not significant. The median follow‑up time of patients with stents due to benign central airway stenosis or obstruction was 51 (range, 0.164‑239) months. Patients with benign disease had a significantly better outcome than patients with malignant disease. For the 19 patients with benign disease, 35 stent procedures were performed as follows: A total of 18 placements, 6 replacements, 3 additional stent placements, 6 removals and 2 stents were repositioned. Patients with benign disease underwent significantly more (≥2) stent‑related procedures than patients with malignant disease. On the whole, the findings of the present study indicate that patients with benign central airway stenosis or obstruction who undergo stenting may require multiple procedures, and that physicians should plan for multiple treatments following the first stent placement as patients with benign airway disease have good long‑term outcomes.

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November-December 2020
Volume 2 Issue 6

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Spandidos Publications style
Iyoda A, Azuma Y, Sano A, Sakai T, Koezuka S, Otsuka H, Isobe K, Sakamoto S, Hata Y, Takagi K, Takagi K, et al: Long‑term outcomes in patients with benign central airway stenosis or obstruction following stenting. World Acad Sci J 2: 20, 2020
APA
Iyoda, A., Azuma, Y., Sano, A., Sakai, T., Koezuka, S., Otsuka, H. ... Takagi, K. (2020). Long‑term outcomes in patients with benign central airway stenosis or obstruction following stenting. World Academy of Sciences Journal, 2, 20. https://doi.org/10.3892/wasj.2020.61
MLA
Iyoda, A., Azuma, Y., Sano, A., Sakai, T., Koezuka, S., Otsuka, H., Isobe, K., Sakamoto, S., Hata, Y., Takagi, K."Long‑term outcomes in patients with benign central airway stenosis or obstruction following stenting". World Academy of Sciences Journal 2.6 (2020): 20.
Chicago
Iyoda, A., Azuma, Y., Sano, A., Sakai, T., Koezuka, S., Otsuka, H., Isobe, K., Sakamoto, S., Hata, Y., Takagi, K."Long‑term outcomes in patients with benign central airway stenosis or obstruction following stenting". World Academy of Sciences Journal 2, no. 6 (2020): 20. https://doi.org/10.3892/wasj.2020.61