Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
World Academy of Sciences Journal
Join Editorial Board Propose a Special Issue
Print ISSN: 2632-2900 Online ISSN: 2632-2919
Journal Cover
November-December 2021 Volume 3 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-December 2021 Volume 3 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Report Open Access

Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021

  • Authors:
    • Mona Kamal Saadeldin
  • View Affiliations / Copyright

    Affiliations: Department of Biosciences, University of Milan, I‑20133 Milan, Italy
    Copyright: © Saadeldin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 64
    |
    Published online on: October 20, 2021
       https://doi.org/10.3892/wasj.2021.135
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Non‑coding RNAs (ncRNAs) are involved in different cellular processes and some of them are considered to play a role in the development of numerous diseases. The recent discovery of ncRNAs is the result of several experimental and bioinformatics studies. On July 21‑23, 2021, the ‘Noncoding RNA World: From Mechanism to Therapy’ conference that was held virtually (originally planned to be held in Basel, Switzerland), gathered experts and researchers from countries worldwide to cover the latest achievements in ncRNA research, including the basic molecular mechanisms and structural biology, bioinformatics, biotechnology, disease development and therapeutics of ncRNAs. The meeting was dominated by a feeling of satisfaction and enthusiasm for the novel discoveries in the ncRNA field that is considered to be relatively new. Intriguingly, several discoveries are added daily beside numerous hurdles that are encountered or remain to be resolved in order for these findings to be translated into clinical practice.
View Figures
View References

1 

Yang Y, Ge H, Li DQ and Xu AX: E2F1-Induced lncRNA BAIAP2-AS1 overexpression contributes to the malignant progression of hepatocellular carcinoma via miR-361-3p/SOX4 axis. Dis Markers. 2021(6256369)2021.PubMed/NCBI View Article : Google Scholar

2 

Hinkel R, Batkai S, Bähr A, Bozoglu T, Straub S, Borchert T, Viereck J, Howe A, Hornaschewitz N, Oberberger L, et al: AntimiR-132 attenuates myocardial hypertrophy in an animal model of percutaneous aortic constriction. J Am Coll Cardiol. 77:2923–2935. 2021.PubMed/NCBI View Article : Google Scholar

3 

Täubel J, Hauke W, Rump S, Viereck J, Batkai S, Poetzsch J, Rode L, Weigt H, Genschel C, Lorch U, et al: Novel antisense therapy targeting microRNA-132 in patients with heart failure: Results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study. Eur Heart J. 42:178–188. 2021.PubMed/NCBI View Article : Google Scholar

4 

Martin SE, Gan H, Toomer G, Sridhar N and Sztuba-Solinska J: The m6A landscape of polyadenylated nuclear (PAN) RNA and its related methylome in the context of KSHV replication. RNA. 27:1102–1125. 2021.PubMed/NCBI View Article : Google Scholar

5 

Pereira M, Ribeiro DR, Pinheiro MM, Ferreira M, Kellner S and Soares AR: m 5 U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs. Int J Mol Sci. 22(2941)2021.PubMed/NCBI View Article : Google Scholar

6 

Youness RA and Gad MZ: Long non-coding RNAs: Functional regulatory players in breast cancer. Noncoding RNA Res. 4:36–44. 2019.PubMed/NCBI View Article : Google Scholar : Erratum in: Noncoding RNA Res 5: 219, 2020.

7 

Kim YK, Kim B and Kim VN: Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis. Proc Natl Acad Sci USA. 113:E1881–E1889. 2016.PubMed/NCBI View Article : Google Scholar

8 

Kwon SC, Nguyen TA, Choi YG, Jo MH, Hohng S, Kim VN and Woo JS: Structure of Human DROSHA. Cell. 164:81–90. 2016.PubMed/NCBI View Article : Google Scholar

9 

Kim B, Jeong K and Kim VN: Genome-wide Mapping of DROSHA Cleavage Sites on Primary MicroRNAs and Noncanonical Substrates. Mol Cell. 66:258–269.e5. 2017.PubMed/NCBI View Article : Google Scholar

10 

Ramilowski JA, Yip CW, Agrawal S, Chang JC, Ciani Y, Kulakovskiy IV, Mendez M, Ooi JLC, Ouyang JF, Parkinson N, et al: Functional annotation of human long noncoding RNAs via molecular phenotyping. Genome Res. 30:1060–1072. 2020.PubMed/NCBI View Article : Google Scholar

11 

Moody J, Kouno T, Suzuki A, Shibayama Y, Terao C, Chang JC, López-Redondo F, Yip CW, Ando Y, Yamamoto K, et al: Profiling of transcribed cis-regulatory elements in single cells. bioRxiv: doi: https://doi.org/10.1101/2021.04.04.438388.

12 

Saadeldin MK, Abdel-Aziz AK and Abdellatif A: Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis. Med Hypotheses. 146(110365)2021.PubMed/NCBI View Article : Google Scholar

13 

Shao W, Bi X, Gao B, Wu J, Pan Y, Yin Y, Liu Z, Zhang W, Jiang X, Ren W, et al: Phase separation of RNA-binding protein promotes polymerase engagement and transcription. bioRxiv: doi: https://doi.org/10.1101/2021.03.26.436939.

14 

Nithin C, Ghosh P and Bujnicki JM: Bioinformatics tools and benchmarks for computational docking and 3D structure prediction of RNA-protein complexes. Genes (Basel). 9(432)2018.PubMed/NCBI View Article : Google Scholar

15 

Ponce-Salvatierra A, Astha Merdas K, Nithin C, Ghosh P, Mukherjee S and Bujnicki JM: Computational modeling of RNA 3D structure based on experimental data. Biosci Rep. 39(BSR20180430)2019.PubMed/NCBI View Article : Google Scholar

16 

Boniecki MJ, Lach G, Dawson WK, Tomala K, Lukasz P, Soltysinski T, Rother KM and Bujnicki JM: SimRNA: A coarse-grained method for RNA folding simulations and 3D structure prediction. Nucleic Acids Res. 44(e63)2016.PubMed/NCBI View Article : Google Scholar

17 

Chen H, Egger M, Xu X, Flemmich L, Krasheninina O, Sun A, Micura R and Ren A: Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding. Nucleic Acids Res. 48:12394–12406. 2020.PubMed/NCBI View Article : Google Scholar

18 

Ishida K, Miyauchi K, Kimura Y, Mito M, Okada S, Suzuki T and Nakagawa S: Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNAH. Genes Cells. 20:887–901. 2015.PubMed/NCBI View Article : Google Scholar

19 

Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarfò R, Peruzzi G, et al: FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. Nat Commun. 8(14741)2017.PubMed/NCBI View Article : Google Scholar

20 

Gandhi M, Groß M, Holler JM, Coggins SAA, Patil N, Leupold JH, Munschauer M, Schenone M, Hartigan CR, Allgayer H, et al: The lncRNA lincNMR regulates nucleotide metabolism via a YBX1-RRM2 axis in cancer. Nat Commun. 11(3214)2020.PubMed/NCBI View Article : Google Scholar

21 

Caudron-Herger M, Rusin SF, Adamo ME, Seiler J, Schmid VK, Barreau E, Kettenbach AN and Diederichs S: R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation. Mol Cell. 75:184–199.e10. 2019.PubMed/NCBI View Article : Google Scholar

22 

Caudron-Herger M, Wassmer E, Nasa I, Schultz A-S, Seiler J, Kettenbach AN and Diederichs S: Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP. Nat Protoc. 15:1338–1370. 2020.PubMed/NCBI View Article : Google Scholar

23 

Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, et al: Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library. Nat Biotechnol. 34:1279–1286. 2016.PubMed/NCBI View Article : Google Scholar

24 

Qu L, Yi Z, Zhu S, Wang C, Cao Z, Zhou Z, Yuan P, Yu Y, Tian F, Liu Z, et al: Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs. Nat Biotechnol. 37:1059–1069. 2019.PubMed/NCBI View Article : Google Scholar : Erratum in: Nat Biotechnol 37: 1380, 2019.

25 

Tichon A, Perry RBT, Stojic L and Ulitsky I: SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA. Genes Dev. 32:70–78. 2018.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
Copy and paste a formatted citation
Spandidos Publications style
Saadeldin MK: Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021. World Acad Sci J 3: 64, 2021.
APA
Saadeldin, M.K. (2021). Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021. World Academy of Sciences Journal, 3, 64. https://doi.org/10.3892/wasj.2021.135
MLA
Saadeldin, M. K."Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021". World Academy of Sciences Journal 3.6 (2021): 64.
Chicago
Saadeldin, M. K."Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021". World Academy of Sciences Journal 3, no. 6 (2021): 64. https://doi.org/10.3892/wasj.2021.135
Copy and paste a formatted citation
x
Spandidos Publications style
Saadeldin MK: Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021. World Acad Sci J 3: 64, 2021.
APA
Saadeldin, M.K. (2021). Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021. World Academy of Sciences Journal, 3, 64. https://doi.org/10.3892/wasj.2021.135
MLA
Saadeldin, M. K."Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021". World Academy of Sciences Journal 3.6 (2021): 64.
Chicago
Saadeldin, M. K."Highlights from the ‘Noncoding RNA world: From Mechanism to Therapy’ conference, July 21-23, 2021". World Academy of Sciences Journal 3, no. 6 (2021): 64. https://doi.org/10.3892/wasj.2021.135
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team