Medical uses for silver nitrate in the urinary tract (Review)

Sekito,Takanori; Sadahira,Takuya; Watanabe,Toyohiko; Maruyama,Yuki; Watanabe,Tomofumi; Iwata,Takehiro; Wada,Koichiro; Edamura,Kohei; Araki,Motoo; Watanabe,Masami

doi:10.3892/wasj.2022.141

Medical uses for silver nitrate in the urinary tract (Review)

Authors:
- Takanori Sekito
- Takuya Sadahira
- Toyohiko Watanabe
- Yuki Maruyama
- Tomofumi Watanabe
- Takehiro Iwata
- Koichiro Wada
- Kohei Edamura
- Motoo Araki
- Masami Watanabe
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Affiliations: Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700‑8558, Japan, Department of Urology, Shimane University School of Medicine, Izumo, Shimane 693‑0021, Japan, Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama 700‑8558, Japan
Published online on: January 21, 2022 https://doi.org/10.3892/wasj.2022.141
Article Number: 6
Copyright : © Sekito et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Silver nitrate has been used for centuries for the treatment of a variety of diseases and in the prevention of infection. Silver nitrate exerts astringent, cauterizing and corrosive effects, as well as antimicrobial activities. Silver nitrate injection therapy has a long history of use in urology. It is reportedly effective for hemorrhagic cystitis, interstitial cystitis, renal hematuria and chyluria. The present review article summarizes the medical applications of silver nitrate in urology. The published studies available on the medical uses of silver nitrate are essentially older and retrospective, involving smaller numbers of patients. In the absence of comparative studies with other treatments, it is thus impossible to determine the relative benefits of silver nitrate. However, the outcomes of silver nitrate therapy have been fairly well established. Silver nitrate therapy may prove to be a treatment option for patients who are poor candidates for invasive treatment. Further studies on the uses of silver nitrate however, are required, and improvements also need to be made in the injection technique to reduce the rate of complications.

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