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Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review

  • Authors:
    • Eko Agus Subagio
    • Galih Indra Permana
    • Abdul Hafid Bajamal
    • Muhammad Faris
    • Nur Setiawan Suroto
    • Amaliya Rasyida
    • Budi Utomo
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Faculty of Medicine, Airlangga University‑Dr. Soetomo General Academic Hospital, Surabaya, East Java 60286, Indonesia, Department of Materials and Metallurgy Engineering, Sepuluh Nopember Institute of Technology, Surabaya, East Java 60111, Indonesia, Department of Public Health, Faculty of Medicine, Airlangga University, Surabaya, East Java 60286, Indonesia
    Copyright: © Subagio et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 37
    |
    Published online on: November 14, 2023
       https://doi.org/10.3892/wasj.2023.214
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Abstract

The best artificial disc material must closely resemble the viscoelasticity, biomechanics and bioavailability of a natural human intervertebral disc. Currently, there is a lack of reviews discussing the characterization of polyvinyl alcohol (PVA) hydrogel as a nucleus pulposus (NP) replacement in intervertebral disc herniation. The present study systematically reviewed the biomechanical characterization of PVA hydrogel as a potential ideal candidate for the replacement of NP. The PubMed, Google Scholar, Science Direct, and Cochrane Database of Systematic Reviews databases were searched according to the Preferred Reporting Items for Systematic Reviews and Meta‑Analyses guideline. Data from the literature regarding study design, sample size, materials and biomechanical properties were collected. The literature search identified seven publications, which were read to obtain information about the biomechanical characteristics of PVA hydrogel material used with different compounds. Stress, strain and Young's modulus testing outcomes were all evaluated. The biomechanical characteristics of the materials were evaluated to determine how closely they resemble those of the NP. The results revealed that the PVA hydrogel and NP share similar biomechanical characteristics. In order to enhance its biomechanical capabilities, the PVA hydrogel may be combined with other materials.
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Copy and paste a formatted citation
Spandidos Publications style
Subagio EA, Permana GI, Bajamal AH, Faris M, Suroto NS, Rasyida A and Utomo B: Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review. World Acad Sci J 5: 37, 2023.
APA
Subagio, E.A., Permana, G.I., Bajamal, A.H., Faris, M., Suroto, N.S., Rasyida, A., & Utomo, B. (2023). Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review. World Academy of Sciences Journal, 5, 37. https://doi.org/10.3892/wasj.2023.214
MLA
Subagio, E. A., Permana, G. I., Bajamal, A. H., Faris, M., Suroto, N. S., Rasyida, A., Utomo, B."Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review". World Academy of Sciences Journal 5.6 (2023): 37.
Chicago
Subagio, E. A., Permana, G. I., Bajamal, A. H., Faris, M., Suroto, N. S., Rasyida, A., Utomo, B."Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review". World Academy of Sciences Journal 5, no. 6 (2023): 37. https://doi.org/10.3892/wasj.2023.214
Copy and paste a formatted citation
x
Spandidos Publications style
Subagio EA, Permana GI, Bajamal AH, Faris M, Suroto NS, Rasyida A and Utomo B: Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review. World Acad Sci J 5: 37, 2023.
APA
Subagio, E.A., Permana, G.I., Bajamal, A.H., Faris, M., Suroto, N.S., Rasyida, A., & Utomo, B. (2023). Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review. World Academy of Sciences Journal, 5, 37. https://doi.org/10.3892/wasj.2023.214
MLA
Subagio, E. A., Permana, G. I., Bajamal, A. H., Faris, M., Suroto, N. S., Rasyida, A., Utomo, B."Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review". World Academy of Sciences Journal 5.6 (2023): 37.
Chicago
Subagio, E. A., Permana, G. I., Bajamal, A. H., Faris, M., Suroto, N. S., Rasyida, A., Utomo, B."Biomechanical properties of polyvinyl alcohol hydrogel as a nucleus pulposus replacement in intervertebral disc herniation: A systematic review". World Academy of Sciences Journal 5, no. 6 (2023): 37. https://doi.org/10.3892/wasj.2023.214
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