Open Access

Apparent excess of mineral corticoids and a point of view of an alternative statistical evaluation: A case report and mini-review of the literature

  • Authors:
    • Fortunata Zirino
    • Vincenzo Calabrese
    • Rossella Siligato
    • Antonella Lipari
    • Federica Giada Vienna
    • Domenico Santoro
  • View Affiliations

  • Published online on: November 28, 2023     https://doi.org/10.3892/wasj.2023.216
  • Article Number: 1
  • Copyright : © Zirino et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The present study describes the case of a 71-year-old male patient with hypocalcemia, hypomagnesemia and hypokalemia. Following infusion therapy, the serum calcium and serum magnesium levels were normalized. Conversely, serum potassium did not respond to the infusion therapy, with the progressive reduction of the serum concentration, in spite of the high dose of potassium infusion. Although unusual, the present study analyzed how infusion treatment affects kalemia. The present study used, over time, the measurements of variables on a single patient as ‘cases’ and the set of measurements of the patient himself (single patient) as a ‘cohort’. One patient can be considered as one single cluster; thus, the independence assumption is not violated. The present study quantitatively analyzed the effect of one or more treatments and in finding unknown causes that may influence the therapeutic response, particularly in situations with a paradoxical response. Thus, it was found that only potassium canreonate was related to an increase in kalemia (β=0.03, P<0.01). Based on this finding, together with the low aldosterone concentration in hypokalemia, an apparent excess of mineral corticoids was assumed.
View Figures
View References

Related Articles

Journal Cover

January-February 2024
Volume 6 Issue 1

Print ISSN: 2632-2900
Online ISSN:2632-2919

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Zirino F, Calabrese V, Siligato R, Lipari A, Vienna FG and Santoro D: Apparent excess of mineral corticoids and a point of view of an alternative statistical evaluation: A case report and mini-review of the literature. World Acad Sci J 6: 1, 2024.
APA
Zirino, F., Calabrese, V., Siligato, R., Lipari, A., Vienna, F.G., & Santoro, D. (2024). Apparent excess of mineral corticoids and a point of view of an alternative statistical evaluation: A case report and mini-review of the literature. World Academy of Sciences Journal, 6, 1. https://doi.org/10.3892/wasj.2023.216
MLA
Zirino, F., Calabrese, V., Siligato, R., Lipari, A., Vienna, F. G., Santoro, D."Apparent excess of mineral corticoids and a point of view of an alternative statistical evaluation: A case report and mini-review of the literature". World Academy of Sciences Journal 6.1 (2024): 1.
Chicago
Zirino, F., Calabrese, V., Siligato, R., Lipari, A., Vienna, F. G., Santoro, D."Apparent excess of mineral corticoids and a point of view of an alternative statistical evaluation: A case report and mini-review of the literature". World Academy of Sciences Journal 6, no. 1 (2024): 1. https://doi.org/10.3892/wasj.2023.216