Mucinous tubular and spindle cell carcinoma: A case report

Ali,Rebaz Haji; Ali,Rawa M.; Ali,Shano M.; Abdullah,Ari M.; Abdullah,Aland Salih; Ali,Alaa Abbas; Hama,Jihad Ibrahim; Pshtiwan,Lana R.A.; Abdalla,Berun A.; Kakamad,Fahmi H.

doi:10.3892/wasj.2024.229

Mucinous tubular and spindle cell carcinoma: A case report

Authors:
- Rebaz Haji Ali
- Rawa M. Ali
- Shano M. Ali
- Ari M. Abdullah
- Aland Salih Abdullah
- Alaa Abbas Ali
- Jihad Ibrahim Hama
- Lana R.A. Pshtiwan
- Berun A. Abdalla
- Fahmi H. Kakamad
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Affiliations: Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46001, Iraq, Hiwa Cancer Hospital Centre, Sulaimani Directorate of Health, Sulaimani, Kurdistan 46001, Iraq, College of Medicine, University of Sulaimani, Sulaimani, Kurdistan 46001, Iraq, Research Center, University of Halabja, Halabja, Kurdistan 46018, Iraq
Published online on: January 30, 2024 https://doi.org/10.3892/wasj.2024.229
Article Number: 14
Copyright : © Ali et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare variant of renal cell carcinoma (RCC). It is predominately observed in adults and is generally considered an indolent variant with a better prognosis relative to the other forms of RCC. The present study describes the case of a 69‑year‑old male patient with a prior history of renal cyst who presented with a 3‑month history of back and abdominal pain. The patient had right‑sided loin tenderness. An abdominal ultrasound showcased a well‑defined hypoechoic lesion, which measured 23x26 mm, found on the lateral aspect of the right kidney. A computed tomography (CT) scan of the chest and abdomen with contrast material revealed evidence of a well‑defined exophytic mass (3x3 cm) within the lower pole of the right kidney. The patient was managed through a right partial nephrectomy, and the histopathological examination confirmed the diagnosis of MTSCC. At 3 months after the surgery, there was no recurrence or distant metastasis on the CT scan of the chest, abdomen and pelvis. Due to its rarity, there is limited information available regarding the treatment of MTSCC. Usually, tumors with no metastasis are managed by surgical excision, while metastatic MTSCCs have a very controversial approach, mainly consisting of immunotherapy. The case described herein underscores the importance of including MTSCC in the differential diagnoses for RCC. Partial nephrectomy and tumor excision may have a good outcome.

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