Testicular cholesterol granuloma mimicking a testicular tumor: A case report

Bapir,Rawa; Abdullah,Ari M.; Tahir,Soran H.; Hama,Nali H.; Hama,Jihad Ibrahim; Abid,Ayoob Asaad Mohammed; Kakamad,Fahmi H.; Abdalla,Berun A.; Aghaways,Ismaeel

doi:10.3892/wasj.2024.232

March-April 2024 Volume 6 Issue 2

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March-April 2024 Volume 6 Issue 2

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Case Report Open Access

Testicular cholesterol granuloma mimicking a testicular tumor: A case report

Authors:
- Rawa Bapir
- Ari M. Abdullah
- Soran H. Tahir
- Nali H. Hama
- Jihad Ibrahim Hama
- Ayoob Asaad Mohammed Abid
- Fahmi H. Kakamad
- Berun A. Abdalla
- Ismaeel Aghaways
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Affiliations: Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46001, Iraq, Research Center, University of Halabja, Halabja, Kurdistan 46018, Iraq, College of Medicine, University of Sulaimani, Sulaimani, Kurdistan 46001, Iraq

Copyright: © Bapir et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 17
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Published online on: February 21, 2024

https://doi.org/10.3892/wasj.2024.232
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Abstract

Cholesterol granulomas (ChGs) are benign fibro‑granulomatous lesions that develop following trauma and inflammation. The most common sites of presentation are the middle ear, paranasal sinuses and petrous apex; however, they can present in any area of the body where cholesterol deposition can occur. The present study describes the case of a 62‑year‑old male who presented with a painless right scrotal mass that had been there for the past 6 years. Upon a physical examination, a hard non‑tender mass at the lower pole of the right testis with normal overlying scrotal skin was detected. Blood analyses revealed normal levels of tumor markers (β‑human chorionic gonadotropin, alpha‑fetoprotein and lactate dehydrogenase) and a normal lipid profile. A right scrotal color Doppler ultrasound revealed a well‑defined hypoechoic 13x14 mm lower pole testicular mass. Scrotal magnetic resonance imaging revealed a well‑defined nodule (13x11x12 mm) at the lower pole of the right testis near the epididymis. Under spinal anesthesia, via inguinal incision, a right partial orchiectomy was performed. The post‑operative period was uneventful. The results of the histopathological examination were consistent with testicular ChG. ChG of the testis is extremely rare, and only one other case has been recorded in the literature to date, at least to the best of our knowledge. Differentiating between ChGs of the testis and testicular tumors before surgery can be relatively challenging. This should be regarded as a differential diagnosis in cases of testicular masses.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Testicular cholesterol granuloma mimicking a testicular tumor: A case report

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